1.0 2010-04-08 22:04:42 UTC 2026-09-18 18:35:40 UTC FDB000760 Chloroform Indirect food additive arising from adhesives and polymers Chloroform is a common solvent in the laboratory because it is relatively unreactive, miscible with most organic liquids, and conveniently volatile. Chloroform is used as a solvent in the pharmaceutical industry and for producing dyes and pesticides. Chloroform is an effective solvent for alkaloids in their base form and thus plant material is commonly extracted with chloroform for pharmaceutical processing. For example, it is commercially used to extract morphine from poppies and scopolamine from Datura plants. Chloroform containing deuterium (heavy hydrogen), CDCl3, is a common solvent used in NMR spectroscopy. It can be used to bond pieces of acrylic glass (also known under the trade names Perspex and Plexiglas). A solvent of phenol:chloroform:isoamyl alcohol 25:24:1 is used to dissolve non-nucleic acid biomolecules in DNA and RNA extractions.; Chloroform is the organic compound with formula CHCl3. It does not undergo combustion in air, although it will burn when mixed with more flammable substances. It is a member of a group of compounds known as trihalomethanes. Chloroform has myriad uses as a reagent and a solvent. It is also considered an environmental hazard. Several million tons are produced annually.; The output of this process is a mixture of the four chloromethanes: chloromethane, dichloromethane, chloroform (trichloromethane), and carbon tetrachloride, which are then separated by distillation. Chloroform is found in spearmint. 1,1,1-Trichloromethane CF CHCl3 Chloroform [NF xvII] Chloroform [UN1888] [Poison] Chloroform, acs Chloroforme Chloroformium pro narcosi Chloroformwith amylene Chloroformwith ethanol Cloroformio Formyl trichloride Freon 20 HSDB 56 Methane trichloride Methane, trichloro- Methenyl chloride Methenyl trichloride Methyl trichloride Methylidyne trichloride R 20 R 20 (refrigerant) R 20 (VAN) R20 Refrigerant R20 TCM Trichloormethaan Trichlormethan Trichloro-methane Trichloroform Trichloromethane Trichloromethane, 9CI Trichloromethyl radical Triclorometano CHCl3 119.378 117.914383153 trichloromethane chloroform 67-66-3 ClC(Cl)Cl InChI=1S/CHCl3/c2-1(3)4/h1H HEDRZPFGACZZDS-UHFFFAOYSA-N belongs to the class of organic compounds known as trihalomethanes. These are organic compounds in which exactly three of the four hydrogen atoms of methane (CH4) are replaced by halogen atoms. Trihalomethanes Organic compounds Organohalogen compounds Alkyl halides Halomethanes Aliphatic acyclic compounds Alkyl chlorides Hydrocarbon derivatives Organochlorides Aliphatic acyclic compound Alkyl chloride Hydrocarbon derivative Organochloride Trihalomethane a small molecule chloromethanes one-carbon compound logp 1.67 ALOGPS logs -1.23 ALOGPS solubility 6.95e+00 g/l ALOGPS melting_point Mp -63.2° logp 1.83 ChemAxon iupac trichloromethane ChemAxon average_mass 119.378 ChemAxon mono_mass 117.914383153 ChemAxon smiles ClC(Cl)Cl ChemAxon formula CHCl3 ChemAxon inchi InChI=1S/CHCl3/c2-1(3)4/h1H ChemAxon inchikey HEDRZPFGACZZDS-UHFFFAOYSA-N ChemAxon polar_surface_area 0 ChemAxon refractivity 21.37 ChemAxon polarizability 8.52 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 0 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::EiMs 293 Specdb::CMs 15025 Specdb::CMs 26913 Specdb::CMs 27188 Specdb::CMs 27232 Specdb::CMs 100343 Specdb::CMs 100344 Specdb::CMs 100345 Specdb::CMs 151429 Specdb::NmrOneD 2578 Specdb::NmrOneD 3274 Specdb::NmrOneD 15722 Specdb::NmrOneD 15723 Specdb::NmrOneD 15724 Specdb::NmrOneD 15725 Specdb::NmrOneD 15726 Specdb::NmrOneD 15727 Specdb::NmrOneD 15728 Specdb::NmrOneD 15729 Specdb::NmrOneD 15730 Specdb::NmrOneD 15731 Specdb::NmrOneD 15732 Specdb::NmrOneD 15733 Specdb::NmrOneD 15734 Specdb::NmrOneD 15735 Specdb::NmrOneD 15736 Specdb::NmrOneD 15737 Specdb::NmrOneD 15738 Specdb::NmrOneD 15739 Specdb::NmrOneD 15740 Specdb::NmrOneD 15741 Specdb::MsMs 99096 Specdb::MsMs 99097 Specdb::MsMs 99098 Specdb::MsMs 164181 Specdb::MsMs 164182 Specdb::MsMs 164183 Specdb::MsMs 2783569 Specdb::MsMs 2783570 Specdb::MsMs 2783571 Specdb::MsMs 2921869 Specdb::MsMs 2921870 Specdb::MsMs 2921871 HMDB29596 35255 MCH #<Reference:0x0000558bea6948f0> #<Reference:0x0000558bea694738> #<Reference:0x0000558bea694580> #<Reference:0x0000558bea6943c8> #<Reference:0x0000558bea694210> #<Reference:0x0000558bea694058> Spearmint Type 1 specific Mentha spicata 29719 Anti bacterial 145 A substance that kills or slows the growth of bacteria. Anti microbial 436 A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. Anti-Zika virus 1441 Antibiotic 147 A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. Carcinogenic 762 A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. Hepatotoxic 984 A role played by a chemical compound exihibiting itself through the ability to induce damage to the liver in animals. Mutagenic 1125 Toxic 1371 A role played by the molecular entity or part thereof which causes the development of a pathological process.