1.02010-04-08 22:04:42 UTC2020-02-24 19:10:13 UTCFDB000760ChloroformIndirect food additive arising from adhesives and polymers
Chloroform is a common solvent in the laboratory because it is relatively unreactive, miscible with most organic liquids, and conveniently volatile. Chloroform is used as a solvent in the pharmaceutical industry and for producing dyes and pesticides. Chloroform is an effective solvent for alkaloids in their base form and thus plant material is commonly extracted with chloroform for pharmaceutical processing. For example, it is commercially used to extract morphine from poppies and scopolamine from Datura plants. Chloroform containing deuterium (heavy hydrogen), CDCl3, is a common solvent used in NMR spectroscopy. It can be used to bond pieces of acrylic glass (also known under the trade names Perspex and Plexiglas). A solvent of phenol:chloroform:isoamyl alcohol 25:24:1 is used to dissolve non-nucleic acid biomolecules in DNA and RNA extractions.; Chloroform is the organic compound with formula CHCl3. It does not undergo combustion in air, although it will burn when mixed with more flammable substances. It is a member of a group of compounds known as trihalomethanes. Chloroform has myriad uses as a reagent and a solvent. It is also considered an environmental hazard. Several million tons are produced annually.; The output of this process is a mixture of the four chloromethanes: chloromethane, dichloromethane, chloroform (trichloromethane), and carbon tetrachloride, which are then separated by distillation. Chloroform is found in spearmint.1,1,1-TrichloromethaneCFCHCl3Chloroform [NF xvII]Chloroform [UN1888] [Poison]Chloroform, acsChloroformeChloroformium pro narcosiChloroformwith amyleneChloroformwith ethanolCloroformioFormyl trichlorideFreon 20HSDB 56Methane trichlorideMethane, trichloro-Methenyl chlorideMethenyl trichlorideMethyl trichlorideMethylidyne trichlorideR 20R 20 (refrigerant)R 20 (VAN)R20Refrigerant R20TCMTrichloormethaanTrichlormethanTrichloro-methaneTrichloroformTrichloromethaneTrichloromethane, 9CITrichloromethyl radicalTriclorometanoCHCl3119.378117.914383153trichloromethanechloroform67-66-3ClC(Cl)ClInChI=1S/CHCl3/c2-1(3)4/h1HHEDRZPFGACZZDS-UHFFFAOYSA-N belongs to the class of organic compounds known as trihalomethanes. These are organic compounds in which exactly three of the four hydrogen atoms of methane (CH4) are replaced by halogen atoms.TrihalomethanesOrganic compoundsOrganohalogen compoundsAlkyl halidesHalomethanesAliphatic acyclic compoundsAlkyl chloridesHydrocarbon derivativesOrganochloridesAliphatic acyclic compoundAlkyl chlorideHydrocarbon derivativeOrganochlorideTrihalomethanea small moleculechloromethanesone-carbon compoundlogp1.67logs-1.23solubility6.95e+00 g/lmelting_pointMp -63.2°logp1.83iupactrichloromethaneaverage_mass119.378mono_mass117.914383153smilesClC(Cl)ClformulaCHCl3inchiInChI=1S/CHCl3/c2-1(3)4/h1HinchikeyHEDRZPFGACZZDS-UHFFFAOYSA-Npolar_surface_area0refractivity21.37polarizability8.52rotatable_bond_count0acceptor_count0donor_count0physiological_charge0formal_charge0Specdb::EiMs293Specdb::CMs15025Specdb::CMs26913Specdb::CMs27188Specdb::CMs27232Specdb::CMs100343Specdb::CMs100344Specdb::CMs100345Specdb::CMs151429Specdb::NmrOneD2578Specdb::NmrOneD3274Specdb::NmrOneD15722Specdb::NmrOneD15723Specdb::NmrOneD15724Specdb::NmrOneD15725Specdb::NmrOneD15726Specdb::NmrOneD15727Specdb::NmrOneD15728Specdb::NmrOneD15729Specdb::NmrOneD15730Specdb::NmrOneD15731Specdb::NmrOneD15732Specdb::NmrOneD15733Specdb::NmrOneD15734Specdb::NmrOneD15735Specdb::NmrOneD15736Specdb::NmrOneD15737Specdb::NmrOneD15738Specdb::NmrOneD15739Specdb::NmrOneD15740Specdb::NmrOneD15741Specdb::MsMs164181Specdb::MsMs164182Specdb::MsMs164183Specdb::MsMs2921869Specdb::MsMs2921870Specdb::MsMs2921871Specdb::MsMs99096Specdb::MsMs99097Specdb::MsMs99098Specdb::MsMs2783569Specdb::MsMs2783570Specdb::MsMs2783571HMDB2959635255MCH#<Reference:0x00005556760cd948>#<Reference:0x00005556760cd790>#<Reference:0x00005556760cd588>#<Reference:0x00005556760cd290>#<Reference:0x00005556760ccfe8>#<Reference:0x00005556760ccd40>SpearmintType 1specificMentha spicata29719