1.0 2010-04-08 22:05:18 UTC 2019-11-26 02:57:16 UTC FDB002281 N-Acetyl-L-cysteine Effective inhibitor of enzymic browning in foods [DFC] N-Acetyl-L-cysteine is a pharmaceutical drug and nutritional supplement used primarily as a mucolytic agent and in the management of paracetamol (acetaminophen) overdose. Other uses include sulfate repletion in conditions, such as autism, where cysteine and related sulfur amino acids may be depleted. N-Acetyl-L-cysteine is a precursor in the formation of the antioxidant glutathione in the body. The thiol group confers antioxidant effects and is able to reduce free radicals. [Wikipedia]. (2R)-2-(Acetylamino)-3-mercaptopropanoic acid (2R)-2-Acetamido-3-sulfanyl-propanoic acid (2R)-2-acetylamino-3-Sulfanylpropanoate (2R)-2-Acetylamino-3-sulfanylpropanoic acid (2R)-2-acetylamino-3-Sulphanylpropanoate (2R)-2-acetylamino-3-Sulphanylpropanoic acid (R)-2-acetylamino-3-Mercaptopropanoate (R)-2-Acetylamino-3-mercaptopropanoic acid (R)-Mercaptate (R)-Mercaptic acid (R)-Mercapturic acid 2-Acetylamino-3-mercapto-propionate 2-Acetylamino-3-mercapto-propionic acid Acetadote Acetein Acetilcisteina Acetylcysteine Acetylcysteinum Airbron Fabrol Fluimicil infantil Fluimucetin Flumucetin Fluprowit L-2-Acetamido-3-mercaptopropanoic acid L-a-acetamido-b-Mercaptopropionate L-a-acetamido-b-Mercaptopropionic acid L-Acetylcysteine L-alpha-acetamido-beta-Mercaptopropionate L-alpha-Acetamido-beta-mercaptopropionic acid L-α-acetamido-β-mercaptopropionate L-α-acetamido-β-mercaptopropionic acid Lysomucil Mercaptate Mercaptic acid Mercapturic acid Mucomyst N-Acety-L-cysteine N-Acetyl cysteine N-Acetyl-3-mercaptoalanine N-Acetyl-L-(+)-cysteine N-Acetyl-L-cysteine N-Acetylcysteine N-Acetylcysteine; L-form NAC NSC 111180 Parvolex Respaire Sodium 2-acetamido-3-mercaptopropionate C5H9NO3S 163.195 163.030313849 (2R)-2-acetamido-3-sulfanylpropanoic acid acetylcysteine 616-91-1 CC(=O)N[C@@H](CS)C(O)=O InChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1 PWKSKIMOESPYIA-BYPYZUCNSA-N belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids. These are n-acylated alpha amino acids which have the L-configuration of the alpha-carbon atom. N-acyl-L-alpha-amino acids Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Aliphatic acyclic compounds Acetamides Alkylthiols Carbonyl compounds Carboxylic acids Cysteine and derivatives Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Organonitrogen compounds Organopnictogen compounds Secondary carboxylic acid amides Acetamide Aliphatic acyclic compound Alkylthiol Carbonyl group Carboxamide group Carboxylic acid Cysteine or derivatives Hydrocarbon derivative Monocarboxylic acid or derivatives N-acyl-l-alpha-amino acid Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Organosulfur compound Secondary carboxylic acid amide L-cysteine derivative N-acetyl-L-amino acid acetylcysteine Solid logp -0.03 ALOGPS logs -1.51 ALOGPS solubility 5.09e+00 g/l ALOGPS melting_point Mp 109-110° logp -0.71 ChemAxon pka_strongest_acidic 3.82 ChemAxon pka_strongest_basic -2 ChemAxon iupac (2R)-2-acetamido-3-sulfanylpropanoic acid ChemAxon average_mass 163.195 ChemAxon mono_mass 163.030313849 ChemAxon smiles CC(=O)N[C@@H](CS)C(O)=O ChemAxon formula C5H9NO3S ChemAxon inchi InChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1 ChemAxon inchikey PWKSKIMOESPYIA-BYPYZUCNSA-N ChemAxon polar_surface_area 66.4 ChemAxon refractivity 37.67 ChemAxon polarizability 15.34 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 3 ChemAxon donor_count 3 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::MsIr 39 Specdb::MsIr 74 Specdb::MsIr 78 Specdb::MsIr 1446 Specdb::MsIr 1447 Specdb::MsIr 1448 Specdb::CMs 1331 Specdb::CMs 8290 Specdb::CMs 29920 Specdb::CMs 31365 Specdb::CMs 38170 Specdb::CMs 131177 Specdb::CMs 138911 Specdb::MsMs 1795 Specdb::MsMs 1796 Specdb::MsMs 1797 Specdb::MsMs 258876 Specdb::MsMs 258877 Specdb::MsMs 258878 Specdb::MsMs 278814 Specdb::MsMs 278815 Specdb::MsMs 278816 Specdb::MsMs 2226661 Specdb::MsMs 2228075 Specdb::MsMs 2228993 Specdb::MsMs 2230438 Specdb::MsMs 2231464 Specdb::MsMs 2231896 Specdb::MsMs 2232291 Specdb::MsMs 2232751 Specdb::MsMs 2233865 Specdb::MsMs 2235063 Specdb::MsMs 2252610 Specdb::MsMs 2253085 Specdb::MsMs 2253395 Specdb::MsMs 2254718 Specdb::MsMs 2254761 Specdb::MsMs 2255157 Specdb::NmrOneD 1783 Specdb::NmrOneD 9842 Specdb::NmrOneD 9843 Specdb::NmrOneD 9844 Specdb::NmrOneD 9845 Specdb::NmrOneD 9846 Specdb::NmrOneD 9847 Specdb::NmrOneD 9848 Specdb::NmrOneD 9849 Specdb::NmrOneD 9850 Specdb::NmrOneD 9851 Specdb::NmrOneD 9852 Specdb::NmrOneD 9853 Specdb::NmrOneD 9854 Specdb::NmrOneD 9855 Specdb::NmrOneD 9856 Specdb::NmrOneD 9857 Specdb::NmrOneD 9858 Specdb::NmrOneD 9859 Specdb::NmrOneD 9860 Specdb::NmrOneD 9861 Specdb::NmrTwoD 1723 HMDB01890 28939 1ZT #<Reference:0x000055ce31be4e20> #<Reference:0x000055ce31be4c68> #<Reference:0x000055ce31be4ab0> #<Reference:0x000055ce31be48f8> #<Reference:0x000055ce31be4740> #<Reference:0x000055ce31be4588> #<Reference:0x000055ce31be43d0> #<Reference:0x000055ce31be4218> #<Reference:0x000055ce31be4060> #<Reference:0x000055ce31be3e58> #<Reference:0x000055ce31be3ca0> #<Reference:0x000055ce31be3ae8> #<Reference:0x000055ce31be3930> #<Reference:0x000055ce31be3778> #<Reference:0x000055ce31be35c0> #<Reference:0x000055ce31be3408> #<Reference:0x000055ce31be3250> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Cow milk, pasteurized, vitamin A + D added, 0% fat Type 2 specific Cow milk, pasteurized, vitamin A + D added, 1% fat Type 2 specific Cow milk, pasteurized, vitamin A + D added, 2% fat Type 2 specific Cow milk, pasteurized, vitamin D added, 3.25% fat Type 2 specific Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Milk (Cow) Type 2 specific Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 Glycine N-acyltransferase Q6IB77 GLYAT Glycine N-acyltransferase-like protein 1 Q969I3 GLYATL1 Glycine N-acyltransferase-like protein 2 Q8WU03 GLYATL2