1.02010-04-08 22:05:35 UTC2020-09-17 15:35:57 UTCFDB0029402-Octenal2-Octenal belongs to the class of organic compounds known as medium-chain aldehydes. These are aldehydes with a chain length containing between 6 and 12 carbon atoms. 2-octenal has a distinct fresh cucumber, fatty or waxy odor as well as a sweet, green or citrus, fatty taste. It is frequently used in perfuming agents and as a flavoring agent in meat products, gravies and soups. 2-octenal is found in olive oil and other essential plant oils and has been found to exhibit antifungal activity against Tricophyton mentagrophytes, Microsporum canis and Candida spp. (PMID: 16920510). 2-octenal is also a known uremic toxin (PMID: 22626821). Uremic toxins tend to accumulate in the blood either through dietary excess or through poor filtration by the kidneys. As a uremic toxin, this compound can cause uremic syndrome. Chronic exposure to uremic toxins can lead to a number of conditions including renal damage, chronic kidney disease and cardiovascular disease. This seems to be mediated by the direct binding or inhibition by uremic toxins of the enzyme NADPH oxidase (especially NOX4 which is abundant in the kidneys and heart) (A7868). Shortness of breath from fluid buildup in the space between the lungs and the chest wall (pleural effusion) can also be present in individuals suffering from uremia. Uremia or uremic syndrome can also cause changes in mental status, such as confusion, reduced awareness, agitation, psychosis, seizures, and coma.FEMA 3215oct-2-enaloct-2-enal (isomer)C8H14O126.1962126.10446507(2Z)-oct-2-enal(2Z)-oct-2-enal2363-89-5CCCCC\C=C/C=OInChI=1S/C8H14O/c1-2-3-4-5-6-7-8-9/h6-8H,2-5H2,1H3/b7-6-LVBXEMGDVWVTGY-SREVYHEPSA-N belongs to the class of organic compounds known as medium-chain aldehydes. These are an aldehyde with a chain length containing between 6 and 12 carbon atoms.Medium-chain aldehydesOrganic compoundsOrganic oxygen compoundsOrganooxygen compoundsCarbonyl compoundsAliphatic acyclic compoundsEnalsHydrocarbon derivativesOrganic oxidesAliphatic acyclic compoundAlpha,beta-unsaturated aldehydeEnalHydrocarbon derivativeMedium-chain aldehydeOrganic oxideLiquidlogp2.92logs-2.55solubility3.57e-01 g/llogp2.54pka_strongest_basic-4.2iupac(2Z)-oct-2-enalaverage_mass126.1962mono_mass126.10446507smilesCCCCC\C=C/C=OformulaC8H14OinchiInChI=1S/C8H14O/c1-2-3-4-5-6-7-8-9/h6-8H,2-5H2,1H3/b7-6-inchikeyLVBXEMGDVWVTGY-SREVYHEPSA-Npolar_surface_area17.07refractivity40.44polarizability15.42rotatable_bond_count5acceptor_count1donor_count0physiological_charge0formal_charge0Specdb::CMs20137Specdb::CMs151131Specdb::MsIr4042Specdb::MsIr4043Specdb::MsMs64095Specdb::MsMs64096Specdb::MsMs64097Specdb::MsMs121155Specdb::MsMs121156Specdb::MsMs121157Specdb::MsMs2767412Specdb::MsMs2767413Specdb::MsMs2767414Specdb::MsMs2911109Specdb::MsMs2911110Specdb::MsMs2911111HMDB30961#<Reference:0x0000555675a31210>AsparagusType 1specificAsparagus officinalis4686CabbageType 1specificBrassica oleracea var. capitata3716CauliflowerType 1specificBrassica oleracea var. botrytis3715fattygreen