Record Information
Version1.0
Creation date2010-04-08 22:05:58 UTC
Update date2018-05-28 23:13:10 UTC
Primary IDFDB003843
Secondary Accession NumbersNot Available
Chemical Information
FooDB Namecis-Carveol
DescriptionCarveol, also known as 5-isopropenyl-2-methyl-2-cyclohexen-1-ol or P-mentha-1,8-dien-6-ol, is a member of the class of compounds known as menthane monoterpenoids. Menthane monoterpenoids are monoterpenoids with a structure based on the o-, m-, or p-menthane backbone. P-menthane consists of the cyclohexane ring with a methyl group and a (2-methyl)-propyl group at the 1 and 4 ring position, respectively. The o- and m- menthanes are much rarer, and presumably arise by alkyl migration of p-menthanes. Carveol is slightly soluble (in water) and an extremely weak acidic compound (based on its pKa). Carveol is a caraway, fresh, and minty tasting compound and can be found in a number of food items such as fruits, rocket salad (sspecies), cumin, and mandarin orange (clementine, tangerine), which makes carveol a potential biomarker for the consumption of these food products. Carveol is a natural unsaturated, monocyclic monoterpenoid alcohol that is a constituent of spearmint essential oil in the form of cis-(−)-carveol. It is a colorless fluid soluble in oils, but insoluble in water and has an odor and flavor that resemble those of spearmint and caraway. Consequently, it is used as a fragrance in cosmetics and as a flavor additive in the food industry .
CAS Number1197-06-4
Structure
Thumb
Synonyms
SynonymSource
5-Isopropenyl-2-methyl-2-cyclohexen-1-olChEBI
p-Mentha-1,8-dien-6-olChEBI
p-Mentha-6,8-dien-2-olChEBI
1-Methyl-4-isopropenyl-6-cyclohexen-2-olHMDB
2-Methyl-5(1-methylethenyl)cyclohex-2-ene-1-olHMDB
2-Methyl-5-(1-methylethenyl)-2-cyclohexen-1-olHMDB
2-Methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-olHMDB
2-Methyl-5-isopropenyl-2-cyclohexen-1-olHMDB
2-Methyl-5-[1-methylethenyl]-2-cyclohexen-1-olHMDB
5-Isopropenyl-2-methylcyclohex-2-en-1-olHMDB
6,8-p-Menthadien-2-olHMDB
FEMA 2247HMDB
p-Mentha-1(6),8-dien-2-olHMDB
(Z)-Carveolmanual
cis-Carveolmanual
p-Mentha-1,8-dien-6-ol; (±)-cis-formdb_source
Predicted Properties
PropertyValueSource
Water Solubility2.82 g/LALOGPS
logP2.41ALOGPS
logP1.99ChemAxon
logS-1.7ALOGPS
pKa (Strongest Acidic)18.21ChemAxon
pKa (Strongest Basic)-1.4ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area20.23 ŲChemAxon
Rotatable Bond Count1ChemAxon
Refractivity48 m³·mol⁻¹ChemAxon
Polarizability18.34 ųChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Chemical FormulaC10H16O
IUPAC name2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-ol
InChI IdentifierInChI=1S/C10H16O/c1-7(2)9-5-4-8(3)10(11)6-9/h4,9-11H,1,5-6H2,2-3H3
InChI KeyBAVONGHXFVOKBV-UHFFFAOYSA-N
Isomeric SMILESCC(=C)C1CC=C(C)C(O)C1
Average Molecular Weight152.237
Monoisotopic Molecular Weight152.120115135
Classification
Description belongs to the class of organic compounds known as menthane monoterpenoids. These are monoterpenoids with a structure based on the o-, m-, or p-menthane backbone. P-menthane consists of the cyclohexane ring with a methyl group and a (2-methyl)-propyl group at the 1 and 4 ring position, respectively. The o- and m- menthanes are much rarer, and presumably arise by alkyl migration of p-menthanes.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassPrenol lipids
Sub ClassMonoterpenoids
Direct ParentMenthane monoterpenoids
Alternative Parents
Substituents
  • P-menthane monoterpenoid
  • Monocyclic monoterpenoid
  • Secondary alcohol
  • Organic oxygen compound
  • Hydrocarbon derivative
  • Organooxygen compound
  • Alcohol
  • Aliphatic homomonocyclic compound
Molecular FrameworkAliphatic homomonocyclic compounds
External Descriptors
Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateNot Available
Physical DescriptionNot Available
Mass CompositionC 78.90%; H 10.59%; O 10.51%DFC
Melting PointNot Available
Boiling PointBp16 108°DFC
Experimental Water SolubilityNot Available
Experimental logPNot Available
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
DensityNot Available
Refractive Indexn19D 1.4779DFC
Spectra
Spectra
Spectrum TypeDescriptionSplash Key
ChemSpider IDNot Available
ChEMBL IDNot Available
KEGG Compound IDNot Available
Pubchem Compound IDNot Available
Pubchem Substance IDNot Available
ChEBI IDNot Available
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDNot Available
CRC / DFC (Dictionary of Food Compounds) IDJXJ97-Y:JST44-V
EAFUS IDNot Available
Dr. Duke IDCIS-CARVEOL
BIGG IDNot Available
KNApSAcK IDNot Available
HET IDNot Available
Flavornet ID1197-06-4
GoodScent IDrw1551481
SuperScent IDNot Available
Wikipedia IDNot Available
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / BioactivitiesNot Available
EnzymesNot Available
PathwaysNot Available
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
Flavours
FlavorCitations
caraway
  1. Arn, H, Acree TE. “Flavornet: A database of aroma compounds based on odor potency in natural products”. Developments in Food Science 40 (1998): 27. doi:10.1016/S0167-4501(98)80029-0
  2. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
Files
MSDSNot Available
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference— Duke, James. 'Dr. Duke's Phytochemical and Ethnobotanical Databases. United States Department of Agriculture.' Agricultural Research Service, Accessed April 27 (2004).