1.0 2010-04-08 22:06:51 UTC 2025-11-18 23:00:08 UTC FDB005819 1,2-Dimethylbenzene Ortho-xylene, o-xylene or 1,2-dimethylbenzen is a member of the class of organic compounds called xylenes. Xylenes are aromatic compounds that contain a benzene ring carrying two methyl groups at different positions around the ring. There are three types of xylene isomers, ortho, meta and para xylene. O-Xylene is a clear, colorless, highly flammable liquid that is not soluble in water. Most o-xylene is produced through the cracking of peteroleum. O-xylene is largely used in the production of phthalic anhydride, which is a precursor to many materials, drugs, and other chemicals (doi:10.1002/14356007.a28_433). O-Xylene has a geranium-like odor. In the plant kingdom o-xylene is found in black walnuts and papaya. It has also been detected, but not quantified in several different foods, such as pepper (C. annuum), green bell peppers, parsley, yellow bell peppers, and red bell peppers. Exposure to xylene can occur via inhalation, ingestion, eye or skin contact. It is primarily metabolized in the liver by oxidation of a methyl group and conjugation with glycine to yield methyl hippuric acid, which is then excreted in the urine. Smaller amounts are eliminated unchanged in the exhaled air (PMID: 21180450). If xylene is ingested one's mouth should be rinsed, and vomiting should not be induced. Exposure of pure xylene to eyes can cause redness and pain. Xylenes are not acutely toxic, for example the LD50 (rat, oral) is 4300 mg/kg. 1,2-dimethyl-benzene ( o-xylene) 1,2-Dimethylbenzene 1,2-Dimethylbenzol 1,2-Xylene 2-xylene 3, 4-Xylene 3,4-Xylene Benzene, 1, 2-dimethyl- Benzene, 1,2-dimethyl- Benzene, dimethyl-, chloromethylated Benzene, o-dimethyl- BENZENE,1,2-DIMETHYL O-dimethylbenzene O-methyltoluene o-Xylene [UN1307] [Flammable liquid] o-XYLENE- D10 O-xylenes O-xylol Ortho-xylene OXE Xylene, o- Xylene, o-isomer C8H10 106.165 106.07825032 1,2-xylene ortho-xylene 95-47-6 CC1=CC=CC=C1C InChI=1S/C8H10/c1-7-5-3-4-6-8(7)2/h3-6H,1-2H3 CTQNGGLPUBDAKN-UHFFFAOYSA-N belongs to the class of organic compounds known as o-xylenes. These are aromatic compounds that contain a o-xylene moiety, which is a monocyclic benzene carrying exactly two methyl groups at the 1- and 2-positions. o-Xylenes Organic compounds Benzenoids Benzene and substituted derivatives Xylenes Aromatic homomonocyclic compounds Aromatic hydrocarbons Unsaturated hydrocarbons Aromatic homomonocyclic compound Aromatic hydrocarbon Hydrocarbon O-xylene Unsaturated hydrocarbon an aromatic compound xylene liquid logp 3.16 ALOGPS logs -2.71 ALOGPS solubility 2.05e-01 g/l ALOGPS melting_point -25.2 oC logp 3 ChemAxon iupac 1,2-xylene ChemAxon average_mass 106.165 ChemAxon mono_mass 106.07825032 ChemAxon smiles CC1=CC=CC=C1C ChemAxon formula C8H10 ChemAxon inchi InChI=1S/C8H10/c1-7-5-3-4-6-8(7)2/h3-6H,1-2H3 ChemAxon inchikey CTQNGGLPUBDAKN-UHFFFAOYSA-N ChemAxon polar_surface_area 0 ChemAxon refractivity 36.14 ChemAxon polarizability 12.96 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 0 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::EiMs 928 Specdb::NmrOneD 4530 Specdb::NmrOneD 4659 Specdb::NmrOneD 5115 Specdb::NmrOneD 5116 Specdb::MsMs 62106 Specdb::MsMs 62107 Specdb::MsMs 62108 Specdb::MsMs 118770 Specdb::MsMs 118771 Specdb::MsMs 118772 Specdb::MsMs 2735105 Specdb::MsMs 2735106 Specdb::MsMs 2735107 Specdb::MsMs 2974317 Specdb::MsMs 2974318 Specdb::MsMs 2974319 Specdb::CMs 2350 Specdb::CMs 26791 Specdb::CMs 27056 Specdb::CMs 29989 Specdb::CMs 102375 Specdb::CMs 102376 Specdb::CMs 102377 Specdb::CMs 132510 Specdb::CMs 140244 HMDB0059851 Black walnut Type 1 specific Juglans nigra 16719 400.0 400.0 400.0 mg/100 g Blackberry Type 1 specific Rubus Cauliflower Type 1 specific Brassica oleracea var. botrytis 3715 Corn Type 1 specific Zea mays 4577 Cucumber Type 1 specific Cucumis sativus 3659 Evergreen blackberry Type 1 specific Rubus laciniatus Papaya Type 1 specific Carica papaya 3649 Sweet cherry Type 1 specific Prunus avium 42229 geranium