1.0 2010-04-08 22:07:22 UTC 2025-11-18 23:03:05 UTC FDB006923 Carnosolic acid Carnosolic acid, also known as carnosolate, is a member of the class of compounds known as diterpenoids. Diterpenoids are terpene compounds formed by four isoprene units. Carnosolic acid is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Carnosolic acid can be found in common sage and rosemary, which makes carnosolic acid a potential biomarker for the consumption of these food products. C20H28O5 348.4333 348.193674006 5,6,9-trihydroxy-1,1-dimethyl-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-4a-carboxylic acid 5,6,9-trihydroxy-7-isopropyl-1,1-dimethyl-2,3,4,9,10,10a-hexahydrophenanthrene-4a-carboxylic acid CC(C)C1=CC2=C(C(O)=C1O)C1(CCCC(C)(C)C1CC2O)C(O)=O InChI=1S/C20H28O5/c1-10(2)11-8-12-13(21)9-14-19(3,4)6-5-7-20(14,18(24)25)15(12)17(23)16(11)22/h8,10,13-14,21-23H,5-7,9H2,1-4H3,(H,24,25) XMKKZBYHMFTMOJ-UHFFFAOYSA-N belongs to the class of organic compounds known as diterpenoids. These are terpene compounds formed by four isoprene units. Diterpenoids Organic compounds Lipids and lipid-like molecules Prenol lipids Diterpenoids Aromatic homopolycyclic compounds 1-hydroxy-4-unsubstituted benzenoids Carbonyl compounds Carboxylic acids Hydrocarbon derivatives Hydrophenanthrenes Monocarboxylic acids and derivatives Naphthalenecarboxylic acids Organic oxides Polyols Secondary alcohols Tetralins 1-hydroxy-4-unsubstituted benzenoid 1-naphthalenecarboxylic acid 1-naphthalenecarboxylic acid or derivatives Abietane diterpenoid Alcohol Aromatic homopolycyclic compound Benzenoid Carbonyl group Carboxylic acid Carboxylic acid derivative Diterpenoid Hydrocarbon derivative Hydrophenanthrene Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organooxygen compound Phenanthrene Polyol Secondary alcohol Tetralin logp 2.96 ALOGPS logs -2.96 ALOGPS solubility 3.81e-01 g/l ALOGPS logp 3.91 ChemAxon pka_strongest_acidic 4.13 ChemAxon pka_strongest_basic -3.1 ChemAxon iupac 5,6,9-trihydroxy-1,1-dimethyl-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-4a-carboxylic acid ChemAxon average_mass 348.4333 ChemAxon mono_mass 348.193674006 ChemAxon smiles CC(C)C1=CC2=C(C(O)=C1O)C1(CCCC(C)(C)C1CC2O)C(O)=O ChemAxon formula C20H28O5 ChemAxon inchi InChI=1S/C20H28O5/c1-10(2)11-8-12-13(21)9-14-19(3,4)6-5-7-20(14,18(24)25)15(12)17(23)16(11)22/h8,10,13-14,21-23H,5-7,9H2,1-4H3,(H,24,25) ChemAxon inchikey XMKKZBYHMFTMOJ-UHFFFAOYSA-N ChemAxon polar_surface_area 97.99 ChemAxon refractivity 94.92 ChemAxon polarizability 37.93 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 5 ChemAxon donor_count 4 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 54393 Specdb::MsMs 54394 Specdb::MsMs 54395 Specdb::MsMs 142533 Specdb::MsMs 142534 Specdb::MsMs 142535 Specdb::MsMs 3603458 Specdb::MsMs 3603459 Specdb::MsMs 3603460 Specdb::MsMs 3603461 Specdb::MsMs 3603462 Specdb::MsMs 3603463 Common sage Type 1 specific Salvia officinalis 38868 210.0 210.0 210.0 mg/100 g Rosemary Type 1 specific Rosmarinus officinalis 39367 Anti hepatotoxic 328 Any compound that is able to prevent damage to the liver. Anti HIV 333 A substance that destroys or inhibits replication of viruses. Anti lipoperoxidant 407 Anti radicular 572 Anti-oxidant 502 A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324. Cytotoxic 859 A role played by the molecular entity or part thereof which causes the development of a pathological process. Protease inhibitor 1262 A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases).