1.0 2010-04-08 22:07:31 UTC 2025-11-18 23:04:26 UTC FDB007244 Glycoxylic acid Glyoxylic acid, also known as alpha-ketoacetic acid or glyoxylate, is a member of the class of compounds known as carboxylic acids. Carboxylic acids are compounds containing a carboxylic acid group with the formula -C(=O)OH. Glyoxylic acid is soluble (in water) and a moderately acidic compound (based on its pKa). Glyoxylic acid can be found in a number of food items such as european chestnut, cowpea, wheat, and common thyme, which makes glyoxylic acid a potential biomarker for the consumption of these food products. Glyoxylic acid can be found primarily in blood, cerebrospinal fluid (CSF), feces, and urine, as well as throughout all human tissues. Glyoxylic acid exists in all living species, ranging from bacteria to humans. In humans, glyoxylic acid is involved in a couple of metabolic pathways, which include alanine metabolism and glycine and serine metabolism. Glyoxylic acid is also involved in several metabolic disorders, some of which include lactic acidemia, pyruvate carboxylase deficiency, 3-phosphoglycerate dehydrogenase deficiency, and hyperglycinemia, non-ketotic. Moreover, glyoxylic acid is found to be associated with transurethral resection of the prostate and primary hyperoxaluria I. Glyoxylic acid or oxoacetic acid is an organic compound. Together with acetic acid, glycolic acid, and oxalic acid, glyoxylic acid is one of the C2 carboxylic acids. It is a colourless solid that occurs naturally and is useful industrially . C2H2O3 74.0355 74.00039393 2-oxoacetic acid glyoxylic acid 298-12-4 OC(=O)C=O InChI=1S/C2H2O3/c3-1-2(4)5/h1H,(H,4,5) HHLFWLYXYJOTON-UHFFFAOYSA-N belongs to the class of organic compounds known as carboxylic acids. Carboxylic acids are compounds containing a carboxylic acid group with the formula -C(=O)OH. Carboxylic acids Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acids Aliphatic acyclic compounds Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Short-chain aldehydes Aldehyde Aliphatic acyclic compound Carbonyl group Carboxylic acid Hydrocarbon derivative Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organooxygen compound Short-chain aldehyde 2-oxo monocarboxylic acid aldehydic acid logp -0.59 ALOGPS logs 0.48 ALOGPS solubility 2.24e+02 g/l ALOGPS logp -0.13 ChemAxon pka_strongest_acidic 2.61 ChemAxon pka_strongest_basic -9.2 ChemAxon iupac 2-oxoacetic acid ChemAxon average_mass 74.0355 ChemAxon mono_mass 74.00039393 ChemAxon smiles OC(=O)C=O ChemAxon formula C2H2O3 ChemAxon inchi InChI=1S/C2H2O3/c3-1-2(4)5/h1H,(H,4,5) ChemAxon inchikey HHLFWLYXYJOTON-UHFFFAOYSA-N ChemAxon polar_surface_area 54.37 ChemAxon refractivity 13.5 ChemAxon polarizability 5.35 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::NmrTwoD 1149 Specdb::CMs 893 Specdb::CMs 2958 Specdb::CMs 31004 Specdb::CMs 37302 Specdb::CMs 162291 Specdb::CMs 1050359 Specdb::MsIr 186 Specdb::MsIr 187 Specdb::MsIr 188 Specdb::NmrOneD 1091 Specdb::NmrOneD 4736 Specdb::NmrOneD 4737 Specdb::NmrOneD 142290 Specdb::NmrOneD 142291 Specdb::NmrOneD 142292 Specdb::NmrOneD 142293 Specdb::NmrOneD 142294 Specdb::NmrOneD 142295 Specdb::NmrOneD 142296 Specdb::NmrOneD 142297 Specdb::NmrOneD 142298 Specdb::NmrOneD 142299 Specdb::NmrOneD 142300 Specdb::NmrOneD 142301 Specdb::NmrOneD 142302 Specdb::NmrOneD 142303 Specdb::NmrOneD 142304 Specdb::NmrOneD 142305 Specdb::NmrOneD 142306 Specdb::NmrOneD 142307 Specdb::NmrOneD 142308 Specdb::NmrOneD 142309 Specdb::EiMs 1251 Specdb::MsMs 171 Specdb::MsMs 172 Specdb::MsMs 173 Specdb::MsMs 2909 Specdb::MsMs 2910 Specdb::MsMs 2911 Specdb::MsMs 11255 Specdb::MsMs 11256 Specdb::MsMs 11257 Specdb::MsMs 17927 Specdb::MsMs 17928 Specdb::MsMs 17929 Specdb::MsMs 437683 Specdb::MsMs 437684 Specdb::MsMs 437685 Specdb::MsMs 2775380 Specdb::MsMs 2775381 Specdb::MsMs 2775382 Specdb::MsMs 2907258 Specdb::MsMs 2907259 Specdb::MsMs 2907260 HMDB0000119 Tamarind Type 1 specific Tamarindus indica 58860