1.0 2011-04-11 17:01:42 UTC 2019-11-26 03:20:54 UTC FDB021812 Aminoadipic acid A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-methyl-D-aspartate; (NMDA). Alpha-aminoadipate is an intermediate in the metabolism of lysine and saccharopine. [HMDB]. Aminoadipic acid is found in many foods, some of which are parsnip, red beetroot, spinach, and green bell pepper. (+/-)-2-aminoadipate (+/-)-2-aminoadipic acid 2-Aminoadipate 2-Aminoadipic acid a-Aminoadipate a-Aminoadipic acid Aad alpha-amino-Adipic acid alpha-Aminoadipate alpha-Aminoadipic acid Aminoadipate DL-2-Aminoadipate DL-2-Aminoadipic acid DL-2-Aminohexanedioate DL-2-Aminohexanedioic acid DL-a-Aminoadipate DL-a-Aminoadipic acid DL-alpha-Aminoadipate DL-alpha-Aminoadipic acid DL-α-aminoadipate DL-α-aminoadipic acid L-2-Aminoadipate L-2-Aminoadipic acid L-2-Aminohexanedioate L-2-Aminohexanedioic acid L-alpha-Aminoadipate L-alpha-Aminoadipic acid α-aminoadipate α-aminoadipic acid C6H11NO4 161.1558 161.068807845 2-aminohexanedioic acid aminoadipic acid 542-32-5 NC(CCCC(O)=O)C(O)=O InChI=1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11) OYIFNHCXNCRBQI-UHFFFAOYSA-N belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). Alpha amino acids Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Aliphatic acyclic compounds Amino acids Amino fatty acids Carbonyl compounds Carboxylic acids Dicarboxylic acids and derivatives Hydrocarbon derivatives Medium-chain fatty acids Monoalkylamines Organic oxides Organopnictogen compounds Aliphatic acyclic compound Alpha-amino acid Amine Amino acid Amino fatty acid Carbonyl group Carboxylic acid Dicarboxylic acid or derivatives Fatty acid Fatty acyl Hydrocarbon derivative Medium-chain fatty acid Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary aliphatic amine Primary amine Dicarboxylic acids amino dicarboxylic acid non-proteinogenic alpha-amino acid Solid logp -3.43 ALOGPS logs -0.69 ALOGPS solubility 3.27e+01 g/l ALOGPS logp -2.8 ChemAxon pka_strongest_acidic 2.01 ChemAxon pka_strongest_basic 9.53 ChemAxon iupac 2-aminohexanedioic acid ChemAxon average_mass 161.1558 ChemAxon mono_mass 161.068807845 ChemAxon smiles NC(CCCC(O)=O)C(O)=O ChemAxon formula C6H11NO4 ChemAxon inchi InChI=1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11) ChemAxon inchikey OYIFNHCXNCRBQI-UHFFFAOYSA-N ChemAxon polar_surface_area 100.62 ChemAxon refractivity 35.89 ChemAxon polarizability 15.53 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 5 ChemAxon donor_count 3 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Lysine Degradation SMP00037 map00310 Specdb::NmrTwoD 1345 Specdb::NmrOneD 1401 Specdb::NmrOneD 4832 Specdb::NmrOneD 4833 Specdb::CMs 16997 Specdb::CMs 32002 Specdb::CMs 37582 Specdb::CMs 99576 Specdb::MsMs 731 Specdb::MsMs 732 Specdb::MsMs 733 Specdb::MsMs 12053 Specdb::MsMs 12054 Specdb::MsMs 12055 Specdb::MsMs 18725 Specdb::MsMs 18726 Specdb::MsMs 18727 Specdb::MsMs 447303 Specdb::MsMs 1471149 Specdb::MsMs 1471324 Specdb::MsMs 1472449 Specdb::MsMs 1472450 Specdb::MsMs 1472451 Specdb::MsMs 1472452 Specdb::MsMs 1472453 Specdb::MsMs 1472454 Specdb::MsMs 1472455 Specdb::MsMs 1472456 Specdb::MsMs 1472457 Specdb::MsMs 1472458 Specdb::MsMs 3602486 Specdb::MsMs 3602487 Specdb::MsMs 3602488 HMDB00510 #<Reference:0x00007f94292baad8> #<Reference:0x00007f94292ba920> #<Reference:0x00007f94292ba768> #<Reference:0x00007f94292ba5b0> #<Reference:0x00007f94292ba3f8> #<Reference:0x00007f94292ba240> #<Reference:0x00007f94292ba088> #<Reference:0x00007f94292b9ed0> #<Reference:0x00007f94292b9d18> #<Reference:0x00007f94292b9b60> #<Reference:0x00007f94292b99a8> #<Reference:0x00007f94292b97f0> #<Reference:0x00007f94292b9638> #<Reference:0x00007f94292b9480> #<Reference:0x00007f94292b92c8> #<Reference:0x00007f94292b9110> Barley Type 1 specific Hordeum vulgare 4513 Broccoli Type 1 specific Brassica oleracea var. italica 36774 54.94 54.94 54.94 mg/100 g Carrot Type 1 specific Daucus carota ssp. sativus 79200 3.55 3.55 3.55 mg/100 g Cow milk, pasteurized, vitamin A + D added, 0% fat Type 2 specific Cow milk, pasteurized, vitamin A + D added, 1% fat Type 2 specific Cow milk, pasteurized, vitamin A + D added, 2% fat Type 2 specific Cow milk, pasteurized, vitamin D added, 3.25% fat Type 2 specific Cucumber Type 1 specific Cucumis sativus 3659 6.07 6.07 6.07 mg/100 g Dill Type 1 specific Anethum graveolens 40922 23.62 23.62 23.62 mg/100 g Eggplant Type 1 specific Solanum melongena 4111 5.47 5.47 5.47 mg/100 g Garden onion Type 1 specific Allium cepa 4679 1.47 1.47 1.47 mg/100 g Green bean Type 1 specific Phaseolus vulgaris 3885 8.3 8.3 8.3 mg/100 g Green bell pepper Type 1 specific Capsicum annuum 4072 0.6 0.6 0.6 mg/100 g Green zucchini Type 1 specific Cucurbita pepo var. cylindrica 10.51 10.51 10.51 mg/100 g Japanese pumpkin Type 1 specific Cucurbita maxima 3661 4.33 4.33 4.33 mg/100 g Milk (Cow) Type 2 specific 66.36 311.0 4.3 uM Parsnip Type 1 specific Pastinaca sativa 4041 1.232386 1.2347712 1.23 mg/100 g Potato Type 1 specific Solanum tuberosum 4113 8.95 8.95 8.95 mg/100 g Red beetroot Type 1 specific Beta vulgaris var. rubra 1.14 1.14 1.14 mg/100 g Red bell pepper Type 1 specific Capsicum annuum 4072 3.662087 3.664173979 3.66 mg/100 g Romaine lettuce Type 1 specific Lactuca sativa L. var. longifolia 3.5 3.5 3.5 mg/100 g Rye Type 1 specific Secale cereale 4550 60.24 85.08 35.4 mg/100 g Spinach Type 1 specific Spinacia oleracea 3562 7.98 7.98 7.98 mg/100 g Sunburst squash (pattypan squash) Type 1 specific Cucurbita pepo var. clypeata 19.1 19.1 19.1 mg/100 g Swiss chard Type 1 specific Beta vulgaris ssp. cicla 1527200 18.421561 18.42312263 18.42 mg/100 g Turnip Type 1 specific Brassica rapa var. rapa 51350 1.45 1.45 1.45 mg/100 g Wheat Type 1 specific Triticum 4564 70.197874 70.2 70.1957475 mg/100 g White cabbage Type 1 specific Brassica oleracea L. var. capitata L. f. alba DC. 7.82 7.82 7.82 mg/100 g Yellow wax bean Type 1 specific Phaseolus vulgaris 3885 12.4 12.4 12.4 mg/100 g Yellow zucchini Type 1 specific Cucurbita pepo var. cylindrica 4.065 7.23 0.9 mg/100 g Acyl-CoA synthetase family member 4 Q4L235 AASDH Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Q9NRN7 AASDHPPT