1.02010-04-08 22:08:06 UTC2020-09-17 15:36:12 UTCFDB008492Cuminyl alcoholCuminol or Cuminyl alcohol, also known as p-cumin-7-ol or 4-Isopropylbenzyl alcohol, belongs to the class of organic compounds known as aromatic monoterpenoids. These are monoterpenoids containing at least one aromatic ring. Monoterpenoids are terpenes that contain 10 carbon atoms and are comprised of two isoprene units. The biosynthesis of monoterpenes is known to occur mainly through the methyl-eritritol-phosphate (MEP) pathway in the plastids (PMID: 7640522). Geranyl diphosphate (GPP) is a key intermediate in the biosynthesis of cyclic monoterpenes. GPP undergoes several cyclization reactions to yield a diverse number of cyclic arrangements. Cuminol is an extremely weak basic (essentially neutral) compound (based on its pKa). Cuminol is an alcohol derivative of p-Cymene. It exists as a clear, colorless liquid that is poorly soluble in water. Cuminol can be used as a food additive or as a cosmetic fragrance. It has a cumin, caraway or spicy, herbal aroma and a similar spicy, herbal or peppery taste. Cuminol is found naturally in a number of plants, spices and foods including cumin seed and cumin oils, caraway eucalyptus oils, thyme, sunflowers, tuermeric, guava fruit and other spices and essential oils. Cumin, a widely used spice, is known to have anti-diabetic properties and two of its phytochemicals: cuminol and cuminaldehyde appear to be among the most active components. Cuminol is a potent insulinotrophic molecule that can enhance insulin secretion by up to 4-fold (in rat islet cells) (PMID: 23507295). It also exhibits strong beta-cell protective action (PMID: 23507295).(4-Isopropylphenyl)methanol4-(1-methylethyl)-benzenemethanol4-(1-methylethyl)benzene methanol4-(1-methylethyl)benzenemethanol4-(1-Methylethyl)benzenemethanol, 9CI4-Isopropyl benzyl alcohol4-ISOPROPYLBENZENEMETHANOL4-Isopropylbenzyl alcoholBenzenemethanol, 4-(1-methylethyl)-Benzyl alcohol, p-isopropyl-Cumic alcoholCumin alcoholCuminic alcoholCuminolcuminol ( p-cymen-7-ol)Cuminyl alcoholCuminylalcoholCumyl alcoholFEMA 2933P-cumic alcoholp-Cumin-7-olp-Cymen-7-olp-Cymen-7-ol, 8CIp-cymene-7-olP-isopropyl benzyl alcoholP-Isopropyl-benzyl alcoholp-Isopropylbenzyl alcoholp-Mentha-1,3,5-trien-7-olpara-Cymen-7-olC10H14O150.221150.104465071[4-(propan-2-yl)phenyl]methanolcuminol536-60-7CC(C)C1=CC=C(CO)C=C1InChI=1S/C10H14O/c1-8(2)10-5-3-9(7-11)4-6-10/h3-6,8,11H,7H2,1-2H3OIGWAXDAPKFNCQ-UHFFFAOYSA-N belongs to the class of organic compounds known as aromatic monoterpenoids. These are monoterpenoids containing at least one aromatic ring.Aromatic monoterpenoidsOrganic compoundsLipids and lipid-like moleculesPrenol lipidsMonoterpenoidsAromatic homomonocyclic compoundsAromatic alcoholsBenzyl alcoholsCumenesHydrocarbon derivativesMonocyclic monoterpenoidsPhenylpropanesPrimary alcoholsAlcoholAromatic alcoholAromatic homomonocyclic compoundAromatic monoterpenoidBenzenoidBenzyl alcoholCumeneHydrocarbon derivativeMonocyclic benzene moietyMonocyclic monoterpenoidOrganic oxygen compoundOrganooxygen compoundP-cymenePhenylpropanePrimary alcoholCyclic monoterpenesa small moleculebenzyl alcoholslogp2.63logs-2.36solubility6.51e-01 g/lmelting_point28 oClogp2.45pka_strongest_acidic15.05pka_strongest_basic-2.8iupac[4-(propan-2-yl)phenyl]methanolaverage_mass150.221mono_mass150.104465071smilesCC(C)C1=CC=C(CO)C=C1formulaC10H14OinchiInChI=1S/C10H14O/c1-8(2)10-5-3-9(7-11)4-6-10/h3-6,8,11H,7H2,1-2H3inchikeyOIGWAXDAPKFNCQ-UHFFFAOYSA-Npolar_surface_area20.23refractivity47.06polarizability17.98rotatable_bond_count2acceptor_count1donor_count1physiological_charge0formal_charge0Specdb::EiMs1719Specdb::NmrOneD3899Specdb::NmrOneD4173Specdb::MsIr4925Specdb::MsIr4926Specdb::MsMs52209Specdb::MsMs52210Specdb::MsMs52211Specdb::MsMs145740Specdb::MsMs145741Specdb::MsMs145742Specdb::MsMs1470974Specdb::MsMs1478253Specdb::MsMs1478254Specdb::MsMs1478255Specdb::MsMs1478256Specdb::MsMs1478257Specdb::MsMs1478258Specdb::MsMs1478259Specdb::MsMs1478260Specdb::MsMs1478261Specdb::MsMs1478262Specdb::MsMs1478263Specdb::MsMs1478264Specdb::MsMs1478265Specdb::MsMs1478266Specdb::MsMs1478267Specdb::MsMs1478268Specdb::MsMs1478269Specdb::MsMs1478270Specdb::CMs5564Specdb::CMs27955Specdb::CMs28588Specdb::CMs32231Specdb::CMs42631Specdb::CMs100964Specdb::CMs100965Specdb::CMs100966Specdb::CMs136109Specdb::CMs143843HMDB31817#<Reference:0x0000555674e21fd8>BlackberryType 1specificRubusCommon thymeType 1specificThymus vulgaris49992CuminType 1specificCuminum cyminum524621098.01098.01098.0mg/100 gEvergreen blackberryType 1specificRubus laciniatusHerbs and SpicesUnknowngenericPeppermintType 1specificMentha X piperita342560.000550.000550.00055mg/100 gPot marjoramType 1specificOriganum onites4524160.00.00.0mg/100 gRocket salad (ssp.)Type 1specificEruca vesicaria ssp. sativa29727SunflowerType 1specificHelianthus annuus4232Sweet bayType 1specificLaurus nobilis85223TurmericType 1specificCurcuma longa136217carawaycuminherbherballeatherspicystrongwoodflavor936A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell.