1.0 2010-04-08 22:08:43 UTC 2025-11-18 23:17:05 UTC FDB009612 Hydroxypropyl cellulose Hydroxypropyl cellulose (cellulose, 2-hydroxypropyl ether) is a derivative of cellulose with both water solubility and organic solubility. Hydroxypropyl cellulose acts to stabilize and thicken the precorneal tear film and prolong the tear film breakup time which is usually accelerated in patients with dry eye states. Hydroxypropyl cellulose also acts to lubricate and protect the eye. Hydroxypropyl cellulose usually reduces the signs and symptoms resulting from moderate to severe dry eye syndromes, such as conjunctival hyperemia, corneal and conjunctival staining with rose bengal, exudation, itching, burning, foreign body sensation, smarting, photophobia, dryness and blurred or cloudy vision. Progressive visual deterioration which occurs in some patients may be retarded, halted, or sometimes reversed. 3-Hydroxy-2-phenyl-4-quinolinecarboxylic acid 3-Hydroxy-2-phenyl-cinchoninic acid 3-Hydroxy-2-phenylcinchoninic acid 3-hydroxy-2-phenylquinoline-4-carboxylic acid 3-Hydroxycinchophen 4-Quinolinecarboxylic acid, 3-hydroxy-2-phenyl- 4-Quinolinecarboxylic acid, 3-hydroxy-2-phenyl- (9CI) Chinoxone Cinchoninic acid, 3-hydroxy-2-phenyl- Fenidrone HPC HPC (van) Hydroxycinchophene Lacrisert Magnofenyl Magnophenyl Oxicinchophenum Oxicincofeno Oxinofen Oxycinchophen Oxycinchophen (inn) Oxycinchophen [inn:ban] Oxycinchophene Oxycinchophenum Reumartril Sintofene C16H11NO3 265.2634 265.073893223 3-hydroxy-2-phenylquinoline-4-carboxylic acid oxycinchophen 9004-64-2 OC(=O)C1=C(O)C(=NC2=CC=CC=C12)C1=CC=CC=C1 InChI=1S/C16H11NO3/c18-15-13(16(19)20)11-8-4-5-9-12(11)17-14(15)10-6-2-1-3-7-10/h1-9,18H,(H,19,20) XAPRFLSJBSXESP-UHFFFAOYSA-N belongs to the class of organic compounds known as phenylquinolines. These are heterocyclic compounds containing a quinoline moiety substituted with a phenyl group. Phenylquinolines Organic compounds Organoheterocyclic compounds Quinolines and derivatives Phenylquinolines Aromatic heteropolycyclic compounds Azacyclic compounds Benzene and substituted derivatives Carboxylic acids Heteroaromatic compounds Hydrocarbon derivatives Hydroxypyridines Hydroxyquinolines Monocarboxylic acids and derivatives Organic oxides Organonitrogen compounds Organooxygen compounds Organopnictogen compounds Phenylpyridines Pyridinecarboxylic acids Quinoline carboxylic acids Vinylogous acids 2-phenylpyridine Aromatic heteropolycyclic compound Azacycle Benzenoid Carboxylic acid Carboxylic acid derivative Heteroaromatic compound Hydrocarbon derivative Hydroxypyridine Hydroxyquinoline Monocarboxylic acid or derivatives Monocyclic benzene moiety Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenylquinoline Pyridine Pyridine carboxylic acid Pyridine carboxylic acid or derivatives Quinoline-4-carboxylic acid Vinylogous acid logp 3.86 ALOGPS logs -3.49 ALOGPS solubility 8.49e-02 g/l ALOGPS logp 3.94 ChemAxon pka_strongest_acidic 3.36 ChemAxon pka_strongest_basic 1.72 ChemAxon iupac 3-hydroxy-2-phenylquinoline-4-carboxylic acid ChemAxon average_mass 265.2634 ChemAxon mono_mass 265.073893223 ChemAxon smiles OC(=O)C1=C(O)C(=NC2=CC=CC=C12)C1=CC=CC=C1 ChemAxon formula C16H11NO3 ChemAxon inchi InChI=1S/C16H11NO3/c18-15-13(16(19)20)11-8-4-5-9-12(11)17-14(15)10-6-2-1-3-7-10/h1-9,18H,(H,19,20) ChemAxon inchikey XAPRFLSJBSXESP-UHFFFAOYSA-N ChemAxon polar_surface_area 70.42 ChemAxon refractivity 73.98 ChemAxon polarizability 27.36 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 15224 Specdb::CMs 42813 Specdb::MsMs 71013 Specdb::MsMs 71014 Specdb::MsMs 71015 Specdb::MsMs 129594 Specdb::MsMs 129595 Specdb::MsMs 129596 HMDB32337 #<Reference:0x000055ce317e5cc0> #<Reference:0x000055ce317e5b08> #<Reference:0x000055ce317e5950> #<Reference:0x000055ce317e5798> odorless