1.0 2010-04-08 22:10:01 UTC 2025-11-18 23:34:25 UTC FDB012158 Serotonin Isolated from bananas and other fruitsand is also from cotton (Gossypium hirsutum) [DFC]. Serotonin is found in many foods, some of which are common pea, eggplant, swiss chard, and dill. 3-(2-Aminoethyl)-1H-indol-5-ol 3-(2-Aminoethyl)-1H-indol-5-ol, 9CI 3-(2-Aminoethyl)-5-hydroxyindole 3-(2-Aminoethyl)indol-5-ol 3-(b-Aminoethyl)-5-hydroxyindole 5-HT 5-HTA 5-Hydroxy-3-(b-aminoethyl)indole 5-Hydroxy-tryptamine 5-Hydroxyltryptamine 5-Hydroxytriptamine 5HT Antemovis Anthemovister DS substance Enteramin Enteramine Hippophaine Serotonin Serotonine Thrombocytin Thrombotonin C10H12N2O 176.2151 176.094963016 3-(2-aminoethyl)-1H-indol-5-ol serotonin 50-67-9 NCCC1=CNC2=CC=C(O)C=C12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N belongs to the class of organic compounds known as serotonins. Serotonins are compounds containing a serotonin moiety, which consists of an indole that bears an aminoethyl a position 2 and a hydroxyl group at position 5. Serotonins Organic compounds Organoheterocyclic compounds Indoles and derivatives Tryptamines and derivatives Aromatic heteropolycyclic compounds 1-hydroxy-2-unsubstituted benzenoids 2-arylethylamines 3-alkylindoles Aralkylamines Azacyclic compounds Heteroaromatic compounds Hydrocarbon derivatives Hydroxyindoles Monoalkylamines Organooxygen compounds Organopnictogen compounds Substituted pyrroles 1-hydroxy-2-unsubstituted benzenoid 2-arylethylamine 3-alkylindole Amine Aralkylamine Aromatic heteropolycyclic compound Azacycle Benzenoid Heteroaromatic compound Hydrocarbon derivative Hydroxyindole Indole Organic nitrogen compound Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary aliphatic amine Primary amine Pyrrole Serotonin Substituted pyrrole Biogenic amines Indole alkaloids monoamine molecular messenger phenols primary amino compound tryptamines Solid logp 0.56 ALOGPS logs -1.85 ALOGPS solubility 2.50e+00 g/l ALOGPS melting_point 167.5 oC logp 0.48 ChemAxon pka_strongest_acidic 9.31 ChemAxon pka_strongest_basic 10 ChemAxon iupac 3-(2-aminoethyl)-1H-indol-5-ol ChemAxon average_mass 176.2151 ChemAxon mono_mass 176.094963016 ChemAxon smiles NCCC1=CNC2=CC=C(O)C=C12 ChemAxon formula C10H12N2O ChemAxon inchi InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 ChemAxon inchikey QZAYGJVTTNCVMB-UHFFFAOYSA-N ChemAxon polar_surface_area 62.04 ChemAxon refractivity 52.35 ChemAxon polarizability 19.31 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 2 ChemAxon donor_count 3 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon Tryptophan Metabolism SMP00063 map00380 Specdb::NmrTwoD 1244 Specdb::CMs 496 Specdb::CMs 497 Specdb::CMs 498 Specdb::CMs 499 Specdb::CMs 500 Specdb::CMs 501 Specdb::CMs 1989 Specdb::CMs 2003 Specdb::CMs 6026 Specdb::CMs 29578 Specdb::CMs 30400 Specdb::CMs 30401 Specdb::CMs 30689 Specdb::CMs 30690 Specdb::CMs 30819 Specdb::CMs 30820 Specdb::CMs 31105 Specdb::CMs 31106 Specdb::CMs 37390 Specdb::CMs 145989 Specdb::CMs 1056371 Specdb::CMs 1056373 Specdb::CMs 1056375 Specdb::CMs 1056377 Specdb::CMs 1056379 Specdb::MsIr 360 Specdb::MsIr 361 Specdb::MsIr 362 Specdb::NmrOneD 1294 Specdb::NmrOneD 6302 Specdb::NmrOneD 6303 Specdb::NmrOneD 6304 Specdb::NmrOneD 6305 Specdb::NmrOneD 6306 Specdb::NmrOneD 6307 Specdb::NmrOneD 6308 Specdb::NmrOneD 6309 Specdb::NmrOneD 6310 Specdb::NmrOneD 6311 Specdb::NmrOneD 6312 Specdb::NmrOneD 6313 Specdb::NmrOneD 6314 Specdb::NmrOneD 6315 Specdb::NmrOneD 6316 Specdb::NmrOneD 6317 Specdb::NmrOneD 6318 Specdb::NmrOneD 6319 Specdb::NmrOneD 6320 Specdb::NmrOneD 6321 Specdb::MsMs 451 Specdb::MsMs 452 Specdb::MsMs 453 Specdb::MsMs 3791 Specdb::MsMs 3792 Specdb::MsMs 3793 Specdb::MsMs 3794 Specdb::MsMs 3795 Specdb::MsMs 3796 Specdb::MsMs 3803 Specdb::MsMs 3804 Specdb::MsMs 241597 Specdb::MsMs 241598 Specdb::MsMs 241599 Specdb::MsMs 243652 Specdb::MsMs 243653 Specdb::MsMs 243654 Specdb::MsMs 439726 Specdb::MsMs 445336 Specdb::MsMs 445337 Specdb::MsMs 445338 Specdb::MsMs 445339 Specdb::MsMs 446966 Specdb::MsMs 446967 Specdb::MsMs 446968 HMDB00259 SRO #<Reference:0x000055ce30dcf308> #<Reference:0x000055ce30dcf150> #<Reference:0x000055ce30dcef98> #<Reference:0x000055ce30dcede0> #<Reference:0x000055ce30dcec28> #<Reference:0x000055ce30dcea70> #<Reference:0x000055ce30dce8b8> #<Reference:0x000055ce30dce700> #<Reference:0x000055ce30dce520> #<Reference:0x000055ce30dce2c8> #<Reference:0x000055ce30dce0e8> #<Reference:0x000055ce30dcde90> #<Reference:0x000055ce30dcdc88> #<Reference:0x000055ce30dcd2b0> #<Reference:0x000055ce30dccf68> #<Reference:0x000055ce30dccc70> #<Reference:0x000055ce30dcc298> #<Reference:0x000055ce30dcc0e0> #<Reference:0x000055ce30dc79c8> #<Reference:0x000055ce30dc7810> #<Reference:0x000055ce30dc7658> Anatidae Type 1 specific Anatidae 8830 Avocado Type 1 specific Persea americana 3435 Banana Type 1 specific Musa acuminata 4641 Barley Type 1 specific Hordeum vulgare 4513 1.352141 1.354282342 1.35 mg/100 g Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Bitter gourd Type 1 specific Momordica charantia 3673 Black walnut Type 1 specific Juglans nigra 16719 Broccoli Type 1 specific Brassica oleracea var. italica 36774 Buffalo Type 1 specific Bubalus bubalis 89462 Carrot Type 1 specific Daucus carota ssp. sativus 79200 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Cherry tomato Type 1 specific Solanum lycopersicum var. cerasiforme 195583 Chicken Type 1 specific Gallus gallus 9031 Chinese cabbage Type 1 specific Brassica rapa 3711 Cocoa bean Type 1 specific Theobroma cacao 3641 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Common pea Type 1 specific Pisum sativum 3888 Common walnut Type 1 specific Juglans regia 51240 19.95 30.4 9.5 mg/100 g Corn Type 1 specific Zea mays 4577 Cottonseed Type 1 specific Gossypium 3633 Date Type 1 specific Phoenix dactylifera 42345 0.85 0.85 0.85 mg/100 g Deer Type 1 specific Cervidae 9850 Dill Type 1 specific Anethum graveolens 40922 0.02 0.02 0.02 mg/100 g Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Eggplant Type 1 specific Solanum melongena 4111 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European plum Type 1 specific Prunus domestica 3758 European rabbit Type 1 specific Oryctolagus 9984 Fats and oils Unknown generic French plantain Type 1 specific Musa X paradisiaca 89151 Fruits Unknown generic Garden tomato Type 1 specific Solanum lycopersicum 4081 Garden tomato (var.) Type 1 specific Solanum lycopersicum var. lycopersicum 397755 Grape Type 1 specific Vitis 3603 Green bean Type 1 specific Phaseolus vulgaris 3885 0.02 0.02 0.02 mg/100 g Green bell pepper Type 1 specific Capsicum annuum 4072 0.0 0.0 0.0 mg/100 g Green zucchini Type 1 specific Cucurbita pepo var. cylindrica 0.02 0.02 0.02 mg/100 g Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Kiwi Type 1 specific Actinidia chinensis 3625 Mallard duck Type 1 specific Anas platyrhynchos 8839 Milk (Cow) Type 2 specific 0.03 0.03 0.03 mg/100 g Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Nanking cherry Type 1 specific Prunus tomentosa 105667 1.7 1.7 1.7 mg/100 g Oat Type 1 specific Avena sativa 4498 9.76 9.76 9.76 mg/100 g Ostrich Type 1 specific Struthio camelus 8801 Papaya Type 1 specific Carica papaya 3649 Peach Type 1 specific Prunus persica 3760 Pepper (C. frutescens) Type 1 specific Capsicum annuum var. annuum 40321 Pheasant Type 1 specific Phasianus colchicus 9054 Pineapple Type 1 specific Ananas comosus 4615 3.95 3.95 3.95 mg/100 g Pomegranate Type 1 specific Punica granatum 22663 1.2 1.2 1.2 mg/100 g Potato Type 1 specific Solanum tuberosum 4113 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Red beetroot Type 1 specific Beta vulgaris var. rubra 0.05 0.05 0.05 mg/100 g Red bell pepper Type 1 specific Capsicum annuum 4072 0.007 0.007 0.00699914 mg/100 g Rock ptarmigan Type 1 specific Lagopus muta 64668 Rye Type 1 specific Secale cereale 4550 0.885 1.25 0.52 mg/100 g Scarlet bean Type 1 specific Phaseolus coccineus 3886 Sea-buckthornberry Type 1 specific Hippophae rhamnoides 193516 350.0 350.0 350.0 mg/100 g Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Spinach Type 1 specific Spinacia oleracea 3562 0.01 0.01 0.01 mg/100 g Squab Type 1 specific Columba 8931 Swiss chard Type 1 specific Beta vulgaris ssp. cicla 1527200 6.611577 6.613153291 6.61 mg/100 g Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 Yellow wax bean Type 1 specific Phaseolus vulgaris 3885 0.0 0.0 0.0 mg/100 g 5-hydroxytryptamine receptor 1A P08908 HTR1A 5-hydroxytryptamine receptor 1B P28222 HTR1B 5-hydroxytryptamine receptor 1D P28221 HTR1D 5-hydroxytryptamine receptor 1F P30939 HTR1F 5-hydroxytryptamine receptor 3A P46098 HTR3A 5-hydroxytryptamine receptor 4 Q13639 HTR4 5-hydroxytryptamine receptor 7 P34969 HTR7 Aromatic-L-amino-acid decarboxylase P20711 DDC Serotonin N-acetyltransferase Q16613 AANAT Abortifacient 13 A chemical substance that interrupts pregnancy after implantation. Allergenic 43 A chemical compound which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. Analgesic 56 An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. Anti cholinesterase 184 An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8). Anti convulsant 204 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti depressant 223 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti endotoxic 259 Any protective agent counteracting or neutralizing the action of poisons. Anti gastrisecretogogic 291 Anti-aggregant 94 Anti-Alzheimeran 105 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-gastric 290 Anti-mutilation 452 Anti-Parkinsonian 509 A drug used in the treatment of Parkinson's disease. Anti-predatory 542 Anti-reserpine 576 Anti-scoliotic 597 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-Tourette's 663 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Antidote 236 Any protective agent counteracting or neutralizing the action of poisons. Bronchoconstrictor 735 A drug which causes a narrowing of the lumen of a bronchus or bronchiole. Cancer preventive 754 A substance that inhibits or prevents the proliferation of neoplasms. Cardiovascular 773 A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. Cerebrophilic 786 Coagulant 818 Euphoriant 924 Hypertensive 1007 Insecticide 1040 Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects. Myorelaxant 1134 Myostimulant 1135 Neurotransmitter 1161 An endogenous compound that is used to transmit information across the synapse between a neuron and another cell. Oxytocic 1185 A drug that stimulates contraction of the myometrium. Oxytocics are used to induce labour, obstetric at term, to prevent or control postpartum or postabortion haemorrhage, and to assess foetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (abortifacients). Pesticide 1210 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. Secretogogue 1308 Spasmogenic 1320 Succinic-dehydrogenase inhibitor 1333 A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. Teratogenic 1347 A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect. Ulcerogenic 1392 Vasoactive 1411 Vasoconstrictor 1412 Drug used to cause constriction of the blood vessels.