1.0 2010-04-08 22:10:10 UTC 2015-07-20 22:50:13 UTC FDB012436 Oleamide Release agent migrating from food packaging Oleamide is an amide of the fatty acid oleic acid. It is an endogenous substance: it occurs naturally in the body of animals. It accumulates in the cerebrospinal fluid during sleep deprivation and induces sleep in animals. It is being studied as a potential medical treatment for mood and sleep disorders, and cannabinoid-regulated depression.; The mechanism of action of oleamide's sleep inducing effects is an area of current research. It is likely that oleamide interacts with multiple neurotransmitter systems. Oleamide is structurally related to the endogenous cannabinoid anandamide, and has the ability to bind to the CB1 receptor as a full agonist. (9E)-OCTADEC-9-ENAMIDE (9Z)-9-Octadecenamide (9Z)-octadec-9-enamide (cis)-9-Octadecenoate (cis)-9-Octadecenoic acid (cis)-9-Octadecenoic acid amide (Z)-9-Octadecenamide (Z)-Octadec-9-enoate amide (Z)-Octadec-9-enoic acid amide 14C-labeled oleamide 9-Octadecenamide 9-Octadecenamide, (9Z)- 9-Octadecenamide, (Z)- 9-Octadecenamide, (Z)- (9CI) 9-Octadecenoic acid, amide (cis) 9,10-octadecenamide 9Z-Octadecenamide Adogen 73 Aliphatic amide Amide o Armid o Armoslip CP cis-9,10-Octadecenoamide Crodamide o Crodamide o, or Crodamide or Diamide O 200 Diamit O 200 Elaidoylamide ELD Kemamide O Octadecene amide Oleamide Oleate amide Oleic acid amide Oleyl amide Oleylamide Petrac slip-eze Polydis TR 121 Slip-eze Tocris-0878 trans-9,10-octadecenoamide Unislip 1759 C18H35NO 281.4766 281.271864747 (9E)-octadec-9-enimidic acid (9E)-octadec-9-enimidic acid 301-02-0 CCCCCCCC\C=C\CCCCCCCC(N)=O InChI=1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9+ FATBGEAMYMYZAF-MDZDMXLPSA-N belongs to the class of organic compounds known as fatty amides. These are carboxylic acid amide derivatives of fatty acids, that are formed from a fatty acid and an amine. Fatty amides Organic compounds Lipids and lipid-like molecules Fatty Acyls Fatty amides Aliphatic acyclic compounds Carbonyl compounds Hydrocarbon derivatives Organic oxides Organonitrogen compounds Organopnictogen compounds Primary carboxylic acid amides Aliphatic acyclic compound Carbonyl group Carboxamide group Carboxylic acid derivative Fatty amide Hydrocarbon derivative Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary carboxylic acid amide Primary amides Solid logp 7.38 ALOGPS logs -6.24 ALOGPS solubility 1.61e-04 g/l ALOGPS melting_point Mp 75-76° logp 4.15 ChemAxon pka_strongest_acidic 0.31 ChemAxon pka_strongest_basic 13.7 ChemAxon iupac (9E)-octadec-9-enimidic acid ChemAxon average_mass 281.4766 ChemAxon mono_mass 281.271864747 ChemAxon smiles CCCCCCCC\C=C\CCCCCCCC(N)=O ChemAxon formula C18H35NO ChemAxon inchi InChI=1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9+ ChemAxon inchikey FATBGEAMYMYZAF-MDZDMXLPSA-N ChemAxon polar_surface_area 44.08 ChemAxon refractivity 100.16 ChemAxon polarizability 37.96 ChemAxon rotatable_bond_count 15 ChemAxon acceptor_count 2 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 8269 Specdb::CMs 27475 Specdb::MsMs 258750 Specdb::MsMs 258751 Specdb::MsMs 258752 Specdb::MsMs 278688 Specdb::MsMs 278689 Specdb::MsMs 278690 HMDB02117 Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 Aromatic-L-amino-acid decarboxylase P20711 DDC Fatty-acid amide hydrolase 1 O00519 FAAH Fatty-acid amide hydrolase 2 Q6GMR7 FAAH2