1.0 2010-04-08 22:10:15 UTC 2020-09-17 15:42:23 UTC FDB012589 Dimethylamine Dimethylamine, also known as DMA or (CH3)2NH, belongs to the class of organic compounds known as dialkylamines. These are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen. Dimethylamine is a very strong basic compound (based on its pKa). Dimethylamine (DMA) is also classified as a secondary amine. It is a colorless, liquefied and flammable gas with an ammonia and fish-like odor. Dimethylamine is abundantly present in human urine. The main sources of urinary DMA have been reported to include trimethylamine N-oxide, a common food component found in cold-water fish, and asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide (NO) synthesis. ADMA is excreted in the urine in part unmetabolized and in part after hydrolysis to DMA by dimethylarginine dimethylaminohydrolase (DDAH). Statistically significant increases in urinary DMA have been found in individuals after the consumption of fish and seafoods. The highest values were obtained for individuals that consumed coley, squid, whitting, cod, haddock, sardine, skate and swordfish (PMID: 18282650). DMA has also been identified as a uremic toxin according to the European Uremic Toxin Working Group (PMID: 22626821). Industrially, DMA is used as dehairing agent in tanning, in dyes, in rubber polymerization accelerators, in soaps and cleaning compounds and as an agricultural fungicide. In the body, DMA also undergoes nitrosation under weak acid conditions to give dimethlynitrosamine. Recent studies have shown that DMA is a metabolite produced by several species of bacteria including Arthrobacter and Micrococcus (PMID: 11422368). Dimethylamine is also found in cannabis smoke and is volatilized during the combustion of cannabis (https://doi.org/10.1007/978-1-59259-947-9_2). (CH3)2NH Dimethylamine (anhydrous) Dimethylamine anhydrous Dimethylamine anhydrous (dot) Dimethylamine aqueous solution Dimethylamine hydrobromide Dimethylamine solution Dimethylamine, anhydrous [UN1032] [Flammable gas] Dimethylammonium bromide HNMe2 Me2NH Methanamine, n-methyl- Methanamine, n-methyl-, hydrobromide N-methyl-methanamine N-methylmethanamine N-Methylmethanamine (acd/name 4.0) N-Methylmethanamine, 9CI N,n-dimethylamine nchem.125-comp12 C2H7N 45.0837 45.057849229 dimethylamine dimethylamine 124-40-3 CNC InChI=1S/C2H7N/c1-3-2/h3H,1-2H3 ROSDSFDQCJNGOL-UHFFFAOYSA-N belongs to the class of organic compounds known as dialkylamines. These are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen. Dialkylamines Organic compounds Organic nitrogen compounds Organonitrogen compounds Amines Aliphatic acyclic compounds Hydrocarbon derivatives Organopnictogen compounds Aliphatic acyclic compound Hydrocarbon derivative Organopnictogen compound Secondary aliphatic amine methylamines secondary aliphatic amine Liquid logp -0.53 ALOGPS logs 1.06 ALOGPS solubility 5.16e+02 g/l ALOGPS melting_point Mp -96° logp -0.19 ChemAxon pka_strongest_basic 10.52 ChemAxon iupac dimethylamine ChemAxon average_mass 45.0837 ChemAxon mono_mass 45.057849229 ChemAxon smiles CNC ChemAxon formula C2H7N ChemAxon inchi InChI=1S/C2H7N/c1-3-2/h3H,1-2H3 ChemAxon inchikey ROSDSFDQCJNGOL-UHFFFAOYSA-N ChemAxon polar_surface_area 12.03 ChemAxon refractivity 14.69 ChemAxon polarizability 5.75 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 1 ChemAxon donor_count 1 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 20008 Specdb::CMs 29401 Specdb::CMs 99533 Specdb::CMs 137140 Specdb::CMs 144874 Specdb::NmrTwoD 1135 Specdb::MsIr 162 Specdb::MsIr 163 Specdb::MsIr 164 Specdb::EiMs 899 Specdb::NmrOneD 1077 Specdb::NmrOneD 1138 Specdb::NmrOneD 142090 Specdb::NmrOneD 142091 Specdb::NmrOneD 142092 Specdb::NmrOneD 142093 Specdb::NmrOneD 142094 Specdb::NmrOneD 142095 Specdb::NmrOneD 142096 Specdb::NmrOneD 142097 Specdb::NmrOneD 142098 Specdb::NmrOneD 142099 Specdb::NmrOneD 142100 Specdb::NmrOneD 142101 Specdb::NmrOneD 142102 Specdb::NmrOneD 142103 Specdb::NmrOneD 142104 Specdb::NmrOneD 142105 Specdb::NmrOneD 142106 Specdb::NmrOneD 142107 Specdb::NmrOneD 142108 Specdb::NmrOneD 142109 Specdb::NmrOneD 166489 Specdb::MsMs 6123 Specdb::MsMs 6124 Specdb::MsMs 6125 Specdb::MsMs 6126 Specdb::MsMs 6127 Specdb::MsMs 6128 Specdb::MsMs 310543 Specdb::MsMs 310544 Specdb::MsMs 310545 Specdb::MsMs 355297 Specdb::MsMs 355298 Specdb::MsMs 355299 Specdb::MsMs 446053 Specdb::MsMs 446054 Specdb::MsMs 446055 Specdb::MsMs 446056 Specdb::MsMs 446057 Specdb::MsMs 2326977 Specdb::MsMs 2326978 Specdb::MsMs 2326979 Specdb::MsMs 2612029 Specdb::MsMs 2612030 Specdb::MsMs 2612031 HMDB00087 17170 DMN #<Reference:0x000055ce31889618> #<Reference:0x000055ce31889410> #<Reference:0x000055ce31889208> #<Reference:0x000055ce31889050> #<Reference:0x000055ce31888e98> #<Reference:0x000055ce31888ce0> #<Reference:0x000055ce31888b28> #<Reference:0x000055ce31888970> #<Reference:0x000055ce318887b8> #<Reference:0x000055ce31888600> #<Reference:0x000055ce31888448> #<Reference:0x000055ce31888290> #<Reference:0x000055ce318880d8> #<Reference:0x000055ce31883ee8> #<Reference:0x000055ce31883d30> #<Reference:0x000055ce31883b50> Anatidae Type 1 specific Anatidae 8830 Barley Type 1 specific Hordeum vulgare 4513 0.16 0.16 0.16 mg/100 g Beefalo Type 1 specific Bos taurus X Bison bison 297284 Beer Type 2 specific 0.575 0.575 0.575 mg/100 g Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cabbage Type 1 specific Brassica oleracea var. capitata 3716 0.24 0.24 0.24 mg/100 g Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Common grape Type 1 specific Vitis vinifera 29760 Corn Type 1 specific Zea mays 4577 0.23 0.23 0.23 mg/100 g Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 French plantain Type 1 specific Musa X paradisiaca 89151 Grape wine Type 2 specific 0.4 0.4 0.4 mg/100 g Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Milk (Cow) Type 2 specific 14.278571 17.0 9.4 uM Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rice Type 1 specific Oryza sativa 4530 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Soy bean Type 1 specific Glycine max 3847 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 White cabbage Type 1 specific Brassica oleracea L. var. capitata L. f. alba DC. 0.24 0.24 0.24 mg/100 g Wild boar Type 1 specific Sus scrofa 9823 Wild celery Type 1 specific Apium graveolens 4045 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 O95865 DDAH2 Coleoptophile 821 Pesticide 1210 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.