Record Information
Version1.0
Creation date2010-04-08 22:11:15 UTC
Update date2018-05-29 01:11:53 UTC
Primary IDFDB014416
Secondary Accession NumbersNot Available
Chemical Information
FooDB Namealpha-Terpineol
DescriptionFlavouring agent Terpineol is a naturally occurring monoterpene alcohol that has been isolated from a variety of sources such as cajuput oil, pine oil, and petitgrain oil. There are three isomers, alpha-, beta-, and gamma-terpineol, the last two differing only by the location of the double bond. Terpineol is usually a mixture of these isomers with alpha-terpineol as the major constituent. alpha-Terpineol is found in many foods, some of which are cabbage, cardamom, fennel, and lemon grass.
CAS Number98-55-5
Structure
Thumb
Synonyms
SynonymSource
1-alpha-TerpineolChEBI
1-Menthene-8-olChEBI
1-Methyl-4-isopropyl-1-cyclohexen-8-olChEBI
1-Methyl-4-isopropyl-1-cyclohexene-8-olChEBI
2-(4-Methyl-3-cyclohexenyl)-2-propanolChEBI
alpha,alpha,4-Trimethyl-3-cyclohexene-1-methanolChEBI
1-a-TerpineolGenerator
1-α-terpineolGenerator
a,a,4-Trimethyl-3-cyclohexene-1-methanolGenerator
α,α,4-trimethyl-3-cyclohexene-1-methanolGenerator
(+-)-alpha-Terpineolmanual
(1R)-a,a,4-Trimethyl-3-cyclohexene-1-methanolGenerator
(1R)-α,α,4-trimethyl-3-cyclohexene-1-methanolGenerator
(R)-(+)-a-TerpineolGenerator
(R)-(+)-α-terpineolGenerator
(R)-a-TerpineolGenerator
(R)-a,a,4-Trimethylcyclohex-3-ene-1-methanolGenerator
(R)-alpha-TerpineolChEBI
(R)-α-terpineolGenerator
(R)-α,α,4-trimethylcyclohex-3-ene-1-methanolGenerator
α-Terpineolbiospider
α,α,4-Trimethyl-3-Cyclohexene-1-methanolbiospider
2-(4-Methyl-3-cyclohexen-1-yl)-2-propanolbiospider
2-(4-Methylcyclohex-3-en-1-yl)propan-2-olbiospider
2-(4-Methylcyclohex-3-enyl)propan-2-ol (alpha-terpineol)HMDB
3-Cyclohexene-1-methanol, α,α4-trimethyl-biospider
3-Cyclohexene-1-methanol, alpha,alpha,4-trimethyl-biospider
a-Terpineoldb_source
a,a,4-Trimethyl-3-cyclohexene-1-methanol, 9CIdb_source
alpha-TerpinenolHMDB
alpha-Terpineolbiospider
alpha-TerpineoleHMDB
alpha-TerpinolHMDB
alpha,alpha,4-Trimethyl-3-Cyclohexene-1-methanolbiospider
DL-alpha-Terpineolmanual
FEMA 3045db_source
Lily OF valleyHMDB
Menth-1-en-8-olbiospider
TerpenolHMDB
TerpineolHMDB
Terpineol schlechthinHMDB
Predicted Properties
PropertyValueSource
logP2.17ChemAxon
pKa (Strongest Acidic)19.4ChemAxon
pKa (Strongest Basic)-0.87ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area20.23 ŲChemAxon
Rotatable Bond Count1ChemAxon
Refractivity48.46 m³·mol⁻¹ChemAxon
Polarizability19.07 ųChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Chemical FormulaC10H18O
IUPAC name2-(4-methylcyclohex-3-en-1-yl)propan-2-ol
InChI IdentifierInChI=1S/C10H18O/c1-8-4-6-9(7-5-8)10(2,3)11/h4,9,11H,5-7H2,1-3H3
InChI KeyWUOACPNHFRMFPN-UHFFFAOYSA-N
Isomeric SMILESCC1=CCC(CC1)C(C)(C)O
Average Molecular Weight154.253
Monoisotopic Molecular Weight154.1357652
Classification
DescriptionThis compound belongs to the class of organic compounds known as menthane monoterpenoids. These are monoterpenoids with a structure based on the o-, m-, or p-menthane backbone. P-menthane consists of the cyclohexane ring with a methyl group and a (2-methyl)-propyl group at the 1 and 4 ring position, respectively. The o- and m- menthanes are much rarer, and presumably arise by alkyl migration of p-menthanes.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassPrenol lipids
Sub ClassMonoterpenoids
Direct ParentMenthane monoterpenoids
Alternative Parents
Substituents
  • P-menthane monoterpenoid
  • Monocyclic monoterpenoid
  • Tertiary alcohol
  • Organic oxygen compound
  • Hydrocarbon derivative
  • Organooxygen compound
  • Alcohol
  • Aliphatic homomonocyclic compound
Molecular FrameworkAliphatic homomonocyclic compounds
External Descriptors
Ontology
OntologyShould have ontology for this compound
Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateSolid
Physical DescriptionNot Available
Mass CompositionC 77.87%; H 11.76%; O 10.37%DFC
Melting Point37.5 oC
Boiling PointNot Available
Experimental Water Solubility0.71 mg/mL at 25 oCLI,J & PERDUE,EM (1995)
Experimental logP2.98LI,J & PERDUE,EM (1995)
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
DensityNot Available
Refractive IndexNot Available
Spectra
Spectra
Spectrum TypeDescriptionSplash Key
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positivesplash10-0a4i-9100000000-5e78cee1bf957533902eView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-052r-1900000000-b06b43c06bcab8a8b200View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-052k-9600000000-ecd246742e68c77c0135View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-100r-9200000000-7b4cf8729bfcea55f85cView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-0udi-0900000000-cdc8abcd2a8d0f849b01View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-0udj-4900000000-28a4ee193904ac2aac65View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-000b-9400000000-24758c06f5cf794027aaView in MoNA
ChemSpider ID390927
ChEMBL IDNot Available
KEGG Compound IDC09902
Pubchem Compound ID442501
Pubchem Substance IDNot Available
ChEBI ID22469
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDHMDB04043
CRC / DFC (Dictionary of Food Compounds) IDJQJ06-Z:JQJ06-Z
EAFUS ID3608
Dr. Duke IDTERPINEOL|ALPHA-TERPINEOL
BIGG IDNot Available
KNApSAcK IDC00029674
HET IDNot Available
Flavornet ID98-55-5
GoodScent IDrw1011251
SuperScent IDNot Available
Wikipedia IDTerpineol
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / Bioactivities
DescriptorIDDefinitionReference
angiotensin converting enzyme inhibitor35457 An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).DUKE
aldose reductase inhibitor48550 An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21).DUKE
allelopathicDUKE
analgesic35480 An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.DUKE
anestheticDUKE
anti acne50177 A drug used to treat or prevent skin disorders or for the routine care of skin.DUKE
anti allergenic50857 A drug used to treat allergic reactions.DUKE
anti asthmatic49167 A drug used to treat asthma.DUKE
anti bacterial33282 A substance that kills or slows the growth of bacteria.DUKE
anti cancer35610 A substance that inhibits or prevents the proliferation of neoplasms.DUKE
anti cariogenic52217 Any substance introduced into a living organism with therapeutic or diagnostic purpose.DUKE
anti inflammatory35472 A substance that reduces or suppresses inflammation.DUKE
anti proliferantDUKE
anti septic33281 A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.DUKE
anti spasmodic52217 Any substance introduced into a living organism with therapeutic or diagnostic purpose.DUKE
anti tussive52217 Any substance introduced into a living organism with therapeutic or diagnostic purpose.DUKE
cholagogueDUKE
cicatrizantDUKE
culicideDUKE
expectorant52217 Any substance introduced into a living organism with therapeutic or diagnostic purpose.DUKE
flavor48318 A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell.DUKE
insecticide24852 Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.DUKE
insectifuge24852 Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.DUKE
interleukin-6 inhibitor35222 A substance that diminishes the rate of a chemical reaction.DUKE
larvicideDUKE
mosquitofuge24852 Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.DUKE
motor depressantDUKE
nematicide25491 A substance used to destroy pests of the phylum Nematoda (roundworms).DUKE
perfumery48318 A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell.DUKE
pesticide25944 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.DUKE
sedative35717 A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.DUKE
termiticideDUKE
transdermalDUKE
vulnerary73336 A drug used in treating and healing of wounds.DUKE
EnzymesNot Available
PathwaysNot Available
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
Flavours
FlavorCitations
oil
  1. Arn, H, Acree TE. “Flavornet: A database of aroma compounds based on odor potency in natural products”. Developments in Food Science 40 (1998): 27. doi:10.1016/S0167-4501(98)80029-0
anise
  1. Arn, H, Acree TE. “Flavornet: A database of aroma compounds based on odor potency in natural products”. Developments in Food Science 40 (1998): 27. doi:10.1016/S0167-4501(98)80029-0
mint
  1. Arn, H, Acree TE. “Flavornet: A database of aroma compounds based on odor potency in natural products”. Developments in Food Science 40 (1998): 27. doi:10.1016/S0167-4501(98)80029-0
pine
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
terpene
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
lilac
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
citrus
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
woody
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
floral
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
Files
MSDSshow
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference— Duke, James. 'Dr. Duke's Phytochemical and Ethnobotanical Databases. United States Department of Agriculture.' Agricultural Research Service, Accessed April 27 (2004).
— Shinbo, Y., et al. 'KNApSAcK: a comprehensive species-metabolite relationship database.' Plant Metabolomics. Springer Berlin Heidelberg, 2006. 165-181.