1.0 2010-04-08 22:11:19 UTC 2025-11-19 00:47:20 UTC FDB014512 5-Isopropyl-2-methylphenol Carvacrol or 5-isopropyl-2-methylphenol is a naturally occurring organic compound classified as an alkylphenol (containing at least one aromatic ring) although biochemically, it is a monoterpenoid synthesized from isoprene units. Carvacrol is an isoprenoid lipid molecule that is very hydrophobic, practically insoluble in water, and relatively neutral. Carvacrol has a camphor, spice, and thymol taste with a characteristic pungent, warm odor of oregano. Carvacrol is found in highest concentrations in pot marjorams, common thymes, and black walnuts and in lower concentrations in rosemaries, common oregano, and sweet marjorams. Carvacrol was detected in pepper (spice), tamarinds, peppermints, lovages, and sweet basils making carvacrol a potential biomarker for the consumption of these foods. It has been added as a flavoring agent, preservative and fragrance in products. Its bioactivity and toxicological properties have been reviewed (PMID: 24915411). As a constituent of many essential oils, carvocrol was demonstrated to have anti-biofilm and anti-microbial properties (PMID: 30067078) and acts as an anti-viral against the norovirus (PMID: 24779581). 1-Hydroxy-2-methyl-5-isopropylbenzene 1-Methyl-2-hydroxy-4-isopropylbenzene 2-Hydroxy-4-isopropyl-1-methylbenzene 2-Hydroxy-p-cymene 2-Hydroxycymene 2-Methyl-5-(1-methylethyl)-phenol 2-Methyl-5-(1-methylethyl)phenol 2-Methyl-5-isopropylphenol 2-p-Cymenol 3-Isopropyl-6-methyl-phenol 3-Isopropyl-6-methylphenol 5-Isopropyl-2-methyl-phenol 5-Isopropyl-o-cresol 6-methyl-3-isopropylphenol Antioxine BENZENE,2-HYDROXY,4-ISOPROPYL,1-METHYL CARVACROL Carvacrol Cymene-2-ol, p- Cymenol Cymophenol FEMA 2245 Hydroxy-p-cymene Isopropyl-o-cresol Isothymol Isothymol (=2-Isopropyl-4-methyl phenol) Karvakrol Methyl-5-(1-methylethyl)phenol o-Cresol, 5-isopropyl- O-thymol Oxycymol p-Cymen-2-ol P-Cymene-2-ol p-Cymene, 2-hydroxy- p-Mentha-1,3,5-trien-2-ol Phenol, 2-methyl-5-(1-methylethyl)- Phenol, 3-isopropyl-6-methyl- Phenol, 5-isopropyl-2-methyl- C10H14O 150.221 150.104465071 2-methyl-5-(propan-2-yl)phenol carvacrol 499-75-2 CC(C)C1=CC(O)=C(C)C=C1 InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3 RECUKUPTGUEGMW-UHFFFAOYSA-N belongs to the class of organic compounds known as aromatic monoterpenoids. These are monoterpenoids containing at least one aromatic ring. Aromatic monoterpenoids Organic compounds Lipids and lipid-like molecules Prenol lipids Monoterpenoids Aromatic homomonocyclic compounds 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids Cumenes Hydrocarbon derivatives Monocyclic monoterpenoids Organooxygen compounds Ortho cresols Phenylpropanes Toluenes 1-hydroxy-2-unsubstituted benzenoid 1-hydroxy-4-unsubstituted benzenoid Aromatic homomonocyclic compound Aromatic monoterpenoid Benzenoid Cumene Hydrocarbon derivative Monocyclic benzene moiety Monocyclic monoterpenoid O-cresol Organic oxygen compound Organooxygen compound P-cymene Phenol Phenylpropane Toluene Cyclic monoterpenes Menthane monoterpenoids Menthane monoterpenoids botanical anti-fungal agent p-menthane monoterpenoid phenols Liquid logp 3.20 ALOGPS logs -2.50 ALOGPS solubility 4.70e-01 g/l ALOGPS melting_point Mp 3.5° logp 3.43 ChemAxon pka_strongest_acidic 10.42 ChemAxon pka_strongest_basic -5.5 ChemAxon iupac 2-methyl-5-(propan-2-yl)phenol ChemAxon average_mass 150.221 ChemAxon mono_mass 150.104465071 ChemAxon smiles CC(C)C1=CC(O)=C(C)C=C1 ChemAxon formula C10H14O ChemAxon inchi InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3 ChemAxon inchikey RECUKUPTGUEGMW-UHFFFAOYSA-N ChemAxon polar_surface_area 20.23 ChemAxon refractivity 47.27 ChemAxon polarizability 17.88 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 1 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::EiMs 1813 Specdb::MsIr 6998 Specdb::MsIr 6999 Specdb::MsIr 7000 Specdb::NmrOneD 4151 Specdb::NmrOneD 290615 Specdb::NmrOneD 290616 Specdb::NmrOneD 290617 Specdb::NmrOneD 290618 Specdb::NmrOneD 290619 Specdb::NmrOneD 290620 Specdb::NmrOneD 290621 Specdb::NmrOneD 290622 Specdb::NmrOneD 290623 Specdb::NmrOneD 290624 Specdb::NmrOneD 290625 Specdb::NmrOneD 290626 Specdb::NmrOneD 290627 Specdb::NmrOneD 290628 Specdb::NmrOneD 290629 Specdb::NmrOneD 290630 Specdb::NmrOneD 290631 Specdb::NmrOneD 290632 Specdb::NmrOneD 290633 Specdb::NmrOneD 290634 Specdb::MsMs 54396 Specdb::MsMs 54397 Specdb::MsMs 54398 Specdb::MsMs 135315 Specdb::MsMs 135316 Specdb::MsMs 135317 Specdb::MsMs 1474451 Specdb::MsMs 1474557 Specdb::MsMs 2726822 Specdb::MsMs 2726823 Specdb::MsMs 2726824 Specdb::MsMs 2979401 Specdb::MsMs 2979402 Specdb::MsMs 2979403 Specdb::CMs 2374 Specdb::CMs 26894 Specdb::CMs 27702 Specdb::CMs 29489 Specdb::CMs 44552 Specdb::CMs 101751 Specdb::CMs 101752 Specdb::CMs 101753 Specdb::CMs 159941 HMDB35770 #<Reference:0x000055ce318bf240> #<Reference:0x000055ce318bf088> #<Reference:0x000055ce318beed0> #<Reference:0x000055ce318bed18> Black tea Type 1 Black walnut Type 1 specific Juglans nigra 16719 900.0 900.0 900.0 mg/100 g Caraway Type 1 specific Carum carvi 48032 0.0 0.0 0.0 mg/100 g Ceylon cinnamon Type 1 specific Cinnamomum verum 128608 0.0 0.0 0.0 mg/100 g Cloves Type 1 specific Syzygium aromaticum 219868 0.0 0.0 0.0 mg/100 g Common oregano Type 1 specific Origanum vulgare 39352 32.3 32.3 32.3 mg/100 g Common thyme Type 1 specific Thymus vulgaris 49992 936.4 936.4 936.4 mg/100 g Corn Type 1 specific Zea mays 4577 18.0 18.0 18.0 mg/100 g Cumin Type 1 specific Cuminum cyminum 52462 0.0 0.0 0.0 mg/100 g Dill Type 1 specific Anethum graveolens 40922 Ginger Type 1 specific Zingiber officinale 94328 0.0 0.0 0.0 mg/100 g Green tea Type 1 Herbal tea Type 1 Herbs and Spices Unknown generic Hyssop Type 1 specific Hyssopus officinalis 39324 0.1 0.1 0.1 mg/100 g Lovage Type 1 specific Levisticum officinale 48042 Mexican oregano Type 1 specific Lippia graveolens Nutmeg Type 1 specific Myristica fragrans 51089 0.0 0.0 0.0 mg/100 g Pepper (Spice) Type 1 specific Piper nigrum 13216 0.0 0.0 0.0 mg/100 g Peppermint Type 1 specific Mentha X piperita 34256 Pot marjoram Type 1 specific Origanum onites 452416 1405.75 1980.5 831.0 mg/100 g Red tea Type 1 Rosemary Type 1 specific Rosmarinus officinalis 39367 0.55 0.55 0.55 mg/100 g Spearmint Type 1 specific Mentha spicata 29719 Star anise Type 1 specific Illicium verum 124778 0.0 0.0 0.0 mg/100 g Summer savory Type 1 specific Satureja hortensis 49987 322.5 322.5 322.5 mg/100 g Sweet basil Type 1 specific Ocimum basilicum 39350 Sweet bay Type 1 specific Laurus nobilis 85223 0.0 0.0 0.0 mg/100 g Sweet marjoram Type 1 specific Origanum majorana 268884 367.65 367.65 367.65 mg/100 g Tamarind Type 1 specific Tamarindus indica 58860 Tea Type 1 specific Camellia sinensis 4442 Winter savory Type 1 specific Satureja montana 49988 866.25 866.25 866.25 mg/100 g camphor spice thymol woody Allergenic 43 A chemical compound which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. Anesthetic 62 Anti bacterial 145 A substance that kills or slows the growth of bacteria. Anti cholinesterase 184 An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8). Anti diuretic 233 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti prostaglandin 550 A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. Anti radicular 572 Anti septic 603 A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. Anti-Alzheimeran 105 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-atherosclerotic 138 A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. Anti-helmintic 72 A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. Anti-inflammatory 370 A substance that reduces or suppresses inflammation. Anti-melanomic 425 A substance that inhibits or prevents the proliferation of neoplasms. Anti-oxidant 502 A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324. Anti-plaque 531 Anti-spasmodic 619 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-staphylococcic 627 A substance that kills or slows the growth of bacteria. Anti-streptococcic 631 A substance that kills or slows the growth of bacteria. Anti-tussive 674 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Candidicide 756 Carminative 774 Cyclooxygenase inhibitor 849 A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. Enterorelaxant 908 Expectorant 925 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Fungicide 940 A substance used to destroy fungal pests. Insectifuge 1041 Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects. Irritant 1055 Name 936 A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell. Nematicide 1141 A substance used to destroy pests of the phylum Nematoda (roundworms). Pesticide 1210 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. Prostaglandin inhibitor 1255 A compound that inhibits the action of prostaglandins. Tracheorelaxant 1372 Trichomonicide 1379 Vermifuge 1422 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.