1.02010-04-08 22:12:28 UTC2019-11-26 03:13:21 UTCFDB016499KaempferideIsolated from roots of Alpinia officinarum (lesser galangal). Kaempferide is found in many foods, some of which are herbs and spices, cloves, sour cherry, and european plum.1.3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4-benzopyrone3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4-benzopyrone3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one, 9CI3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one3,5,7-Trihydroxy-4'-methoxy-flavone4'-Methoxy-3,5,7-trihydroxy-flavanone4'-Methoxy-3,5,7-trihydroxyflavone4'-Methylkaempferol4'-O-Methylkaempferol5,7-Dihydroxy-4'-methoxyflavonolCampherideFlavanone, 4'-methoxy-3,5,7-trihydroxy-Flavone, 3,5,7-trihydroxy-4'-methoxy-KaemferideKaempferidKaempferideKaempferol 4'-methyl etherKampferideKampherideC16H12O6300.2629300.0633881163,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-onekaempferide491-54-3COC1=CC=C(C=C1)C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1InChI=1S/C16H12O6/c1-21-10-4-2-8(3-5-10)16-15(20)14(19)13-11(18)6-9(17)7-12(13)22-16/h2-7,17-18,20H,1H3SQFSKOYWJBQGKQ-UHFFFAOYSA-N belongs to the class of organic compounds known as flavonols. Flavonols are compounds that contain a flavone (2-phenyl-1-benzopyran-4-one) backbone carrying a hydroxyl group at the 3-position.FlavonolsOrganic compoundsPhenylpropanoids and polyketidesFlavonoidsFlavonesAromatic heteropolycyclic compounds1-hydroxy-2-unsubstituted benzenoids1-hydroxy-4-unsubstituted benzenoids3-hydroxyflavonoids4'-O-methylated flavonoids5-hydroxyflavonoids7-hydroxyflavonoidsAlkyl aryl ethersAnisolesChromonesHeteroaromatic compoundsHydrocarbon derivativesMethoxybenzenesOrganic oxidesOxacyclic compoundsPhenoxy compoundsPolyolsPyranones and derivativesVinylogous acids1-benzopyran1-hydroxy-2-unsubstituted benzenoid1-hydroxy-4-unsubstituted benzenoid3-hydroxyflavone3-hydroxyflavonoid4p-methoxyflavonoid-skeleton5-hydroxyflavonoid7-hydroxyflavonoidAlkyl aryl etherAnisoleAromatic heteropolycyclic compoundBenzenoidBenzopyranChromoneEtherHeteroaromatic compoundHydrocarbon derivativeHydroxyflavonoidMethoxybenzeneMonocyclic benzene moietyOrganic oxideOrganic oxygen compoundOrganoheterocyclic compoundOrganooxygen compoundOxacyclePhenol etherPhenoxy compoundPolyolPyranPyranoneVinylogous acid7-hydroxyflavonolFlavones and FlavonolsFlavones and Flavonolsflavonolsmonomethoxyflavonetrihydroxyflavonelogp2.48logs-3.60solubility7.53e-02 g/lmelting_pointMp 227-229°logp2.61pka_strongest_acidic6.44pka_strongest_basic-3.9iupac3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-oneaverage_mass300.2629mono_mass300.063388116smilesCOC1=CC=C(C=C1)C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1formulaC16H12O6inchiInChI=1S/C16H12O6/c1-21-10-4-2-8(3-5-10)16-15(20)14(19)13-11(18)6-9(17)7-12(13)22-16/h2-7,17-18,20H,1H3inchikeySQFSKOYWJBQGKQ-UHFFFAOYSA-Npolar_surface_area96.22refractivity79.36polarizability29.73rotatable_bond_count2acceptor_count6donor_count3physiological_charge-1formal_charge0Specdb::CMs23635Specdb::CMs45388Specdb::CMs174507Specdb::MsMs285927Specdb::MsMs285928Specdb::MsMs285929Specdb::MsMs285930Specdb::MsMs285931Specdb::MsMs373731Specdb::MsMs373732Specdb::MsMs373733Specdb::MsMs373734Specdb::MsMs373735Specdb::MsMs373736Specdb::MsMs438945Specdb::MsMs438946Specdb::MsMs439137Specdb::MsMs439516Specdb::MsMs439518Specdb::MsMs439520Specdb::MsMs440240Specdb::MsMs440241Specdb::MsMs440242Specdb::MsMs440243Specdb::MsMs440244Specdb::MsMs2226812Specdb::MsMs2227927Specdb::MsMs2229136HMDB374416099#<Reference:0x0000555674041f80>ClovesType 1specificSyzygium aromaticum219868European plumType 1specificPrunus domestica3758GrapefruitType 1specificCitrus X paradisi376560.00.00.0mg/100 gHerbs and SpicesUnknowngenericSour cherryType 1specificPrunus cerasus140311anti inflammatory370A substance that reduces or suppresses inflammation.anti mutagenic451aromatase inhibitor705An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor which interferes with the action of aromatase (EC 1.14.14.14) and so reduces production of estrogenic steroid hormones.quinone-reductase inducer1277topoisomerase-I inhibitor1368A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA.