1.0 2010-04-08 22:15:06 UTC 2019-11-26 03:19:06 UTC FDB020543 L-Fucose A constituent of the polysaccharides obtained from gum tragacanthand is) also found in glycoproteins obtained from milk Fucose is a hexose deoxy sugar with the chemical formula C6H12O5. It is found on N-linked glycans on the mammalian, insect and plant cell surface, and is the fundamental sub-unit of the fucoidan polysaccharide. Alpha1?3 linked core fucose is a suspected carbohydrate antigen for IgE-mediated allergy.; Fucose is a hexose sugar with the chemical formula C6H12O5. It is found on N-linked glycans on the mammalian and plant cell surface. Fucose is secreted in urine when the liver is damaged. Alpha1->3 linked core fucose is a suspected carbohydrate antigen for IgE-mediated allergy. Two structural features distinguish fucose from other six-carbon sugars present in mammals: the lack of a hydroxyl group on the carbon at the 6-position (C-6) and the L-configuration. In fucose-containing glycan structures, fucosylated glycans, fucose can exist as a terminal modification or serve as an attachment point for adding other sugars. (-)-fucose (-)-l-fucose 6-Deoxy-beta-galactose 6-Deoxy-D-galactopyranose 6-Deoxy-delta-galactopyranose 6-Deoxy-L-beta-galactose 6-Deoxy-L-galactopyranose 6-Deoxy-L-galactose 6-Desoxygalactose 6-methyloxane-2,3,4,5-tetrol 6-methyltetrahydropyran-2,3,4,5-tetraol D-threo-aldose FUC Fucopyranose, L- (7CI) Fucose Fucose, l- L-(-)-fucose L-fucopyranose L-fucose L-galactomethylose L-galactopyranose, 6-deoxy- L-Galactopyranose, 6-deoxy- (9CI) L-Galactose, 6-deoxy- Rhodeose C18H36O15 492.4694 492.205420482 (3S,4R,5S,6S)-6-methyloxane-2,3,4,5-tetrol L-fucose 2438-80-4 CC(O)C(O)C(O)C(O)C=O.CC(O)C1OC(O)C(O)C1O.CC1OC(O)C(O)C(O)C1O InChI=1S/3C6H12O5/c1-2(7)5-3(8)4(9)6(10)11-5;1-2-3(7)4(8)5(9)6(10)11-2;1-3(8)5(10)6(11)4(9)2-7/h2*2-10H,1H3;2-6,8-11H,1H3 LSOFIIQFGYOXNZ-UHFFFAOYSA-N belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity. Hexoses Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates Aliphatic heteromonocyclic compounds Hemiacetals Hydrocarbon derivatives Oxacyclic compounds Oxanes Polyols Secondary alcohols Alcohol Aliphatic heteromonocyclic compound Hemiacetal Hexose monosaccharide Hydrocarbon derivative Organoheterocyclic compound Oxacycle Oxane Polyol Secondary alcohol Deoxy sugars L-fucose fucopyranose Solid melting_point Mp 145° (140-141°) logp -1.9 ChemAxon pka_strongest_acidic 11.3 ChemAxon pka_strongest_basic -3.6 ChemAxon iupac (3S,4R,5S,6S)-6-methyloxane-2,3,4,5-tetrol ChemAxon average_mass 492.4694 ChemAxon mono_mass 492.205420482 ChemAxon smiles CC(O)C(O)C(O)C(O)C=O.CC(O)C1OC(O)C(O)C1O.CC1OC(O)C(O)C(O)C1O ChemAxon formula C18H36O15 ChemAxon inchi InChI=1S/3C6H12O5/c1-2(7)5-3(8)4(9)6(10)11-5;1-2-3(7)4(8)5(9)6(10)11-2;1-3(8)5(10)6(11)4(9)2-7/h2*2-10H,1H3;2-6,8-11H,1H3 ChemAxon inchikey LSOFIIQFGYOXNZ-UHFFFAOYSA-N ChemAxon polar_surface_area 90.15 ChemAxon refractivity 34.38 ChemAxon polarizability 15.35 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 5 ChemAxon donor_count 4 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Fructose and Mannose Degradation SMP00064 map00051 Specdb::NmrTwoD 982 Specdb::NmrTwoD 1186 Specdb::MsMs 274 Specdb::MsMs 275 Specdb::MsMs 276 Specdb::MsMs 287509 Specdb::MsMs 287510 Specdb::MsMs 287511 Specdb::MsMs 326374 Specdb::MsMs 326375 Specdb::MsMs 326376 Specdb::CMs 9738 Specdb::CMs 31911 Specdb::CMs 31912 Specdb::CMs 37337 Specdb::CMs 99539 Specdb::CMs 99540 Specdb::NmrOneD 1139 Specdb::NmrOneD 1191 Specdb::NmrOneD 166520 HMDB00174 18287 1AH1 #<Reference:0x000055ce32509938> #<Reference:0x000055ce32509780> #<Reference:0x000055ce325095c8> #<Reference:0x000055ce32509410> #<Reference:0x000055ce32509258> #<Reference:0x000055ce325090a0> #<Reference:0x000055ce32508ee8> #<Reference:0x000055ce32508d30> #<Reference:0x000055ce32508b78> #<Reference:0x000055ce325089c0> #<Reference:0x000055ce32508808> #<Reference:0x000055ce32508650> #<Reference:0x000055ce32508498> #<Reference:0x000055ce325082e0> #<Reference:0x000055ce32508128> #<Reference:0x000055ce32507f48> #<Reference:0x000055ce32507d90> #<Reference:0x000055ce32507bd8> #<Reference:0x000055ce325079f8> #<Reference:0x000055ce32507818> #<Reference:0x000055ce32507660> #<Reference:0x000055ce325074a8> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Caraway Type 1 specific Carum carvi 48032 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Corn Type 1 specific Zea mays 4577 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Flaxseed Type 1 specific Linum usitatissimum 4006 Garden tomato Type 1 specific Solanum lycopersicum 4081 Grape wine Type 2 specific 0.0 0.0 0.0 mg/100 g Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Milk (Cow) Type 2 specific 26.016364 35.0 15.36 uM Milk and milk products Unknown generic Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Mung bean Type 1 specific Vigna radiata 157791 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Potato Type 1 specific Solanum tuberosum 4113 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 Acetylcholinesterase P22303 ACHE L-fucose kinase Q8N0W3 FUK Plasma alpha-L-fucosidase Q9BTY2 FUCA2 Tissue alpha-L-fucosidase P04066 FUCA1