1.02010-04-08 22:06:04 UTC2019-11-26 02:59:45 UTCFDB004048SarkosinSarcosine, also known as N-methylglycine or (methylamino)acetic acid, is a member of the class of compounds known as alpha amino acids. Alpha amino acids are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). Sarcosine is soluble (in water) and a moderately acidic compound (based on its pKa). Sarcosine can be found in peanut, which makes sarcosine a potential biomarker for the consumption of this food product. Sarcosine can be found primarily in most biofluids, including blood, saliva, cerebrospinal fluid (CSF), and feces, as well as in human muscle, prostate and skeletal muscle tissues. Sarcosine exists in all living organisms, ranging from bacteria to humans. In humans, sarcosine is involved in few metabolic pathways, which include glycine and serine metabolism, methionine metabolism, and sarcosine oncometabolite pathway. Sarcosine is also involved in several metabolic disorders, some of which include homocystinuria-megaloblastic anemia due to defect in cobalamin metabolism, cblg complementation type, hyperglycinemia, non-ketotic, hypermethioninemia, and dimethylglycine dehydrogenase deficiency. Moreover, sarcosine is found to be associated with sarcosinemia. Sarcosine is a non-carcinogenic (not listed by IARC) potentially toxic compound.C3H7NO289.093289.0476784732-(methylamino)acetic acidsarcosineCNCC(O)=OInChI=1S/C3H7NO2/c1-4-2-3(5)6/h4H,2H2,1H3,(H,5,6)FSYKKLYZXJSNPZ-UHFFFAOYSA-N belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon).Alpha amino acidsOrganic compoundsOrganic acids and derivativesCarboxylic acids and derivativesAmino acids, peptides, and analoguesAliphatic acyclic compoundsAmino acidsCarbonyl compoundsCarboxylic acidsDialkylaminesHydrocarbon derivativesMonocarboxylic acids and derivativesOrganic oxidesOrganopnictogen compoundsAliphatic acyclic compoundAlpha-amino acidAmineAmino acidCarbonyl groupCarboxylic acidHydrocarbon derivativeMonocarboxylic acid or derivativesOrganic nitrogen compoundOrganic oxideOrganic oxygen compoundOrganonitrogen compoundOrganooxygen compoundOrganopnictogen compoundSecondary aliphatic amineSecondary amineN-alkylglycineN-methyl-amino acidN-methylglycineslogp-3.06logs0.54solubility3.08e+02 g/llogp-3.2pka_strongest_acidic2.06pka_strongest_basic10.35iupac2-(methylamino)acetic acidaverage_mass89.0932mono_mass89.047678473smilesCNCC(O)=OformulaC3H7NO2inchiInChI=1S/C3H7NO2/c1-4-2-3(5)6/h4H,2H2,1H3,(H,5,6)inchikeyFSYKKLYZXJSNPZ-UHFFFAOYSA-Npolar_surface_area49.33refractivity20.78polarizability8.66rotatable_bond_count2acceptor_count3donor_count2physiological_charge0formal_charge0Specdb::EiMs880Specdb::NmrTwoD1011Specdb::NmrTwoD1250Specdb::MsIr372Specdb::MsIr373Specdb::MsIr374Specdb::NmrOneD1224Specdb::NmrOneD1307Specdb::NmrOneD2114Specdb::NmrOneD2807Specdb::NmrOneD143250Specdb::NmrOneD143251Specdb::NmrOneD143252Specdb::NmrOneD143253Specdb::NmrOneD143254Specdb::NmrOneD143255Specdb::NmrOneD143256Specdb::NmrOneD143257Specdb::NmrOneD143258Specdb::NmrOneD143259Specdb::NmrOneD143260Specdb::NmrOneD143261Specdb::NmrOneD143262Specdb::NmrOneD143263Specdb::NmrOneD143264Specdb::NmrOneD143265Specdb::NmrOneD143266Specdb::NmrOneD143267Specdb::NmrOneD143268Specdb::NmrOneD143269Specdb::NmrOneD166453Specdb::CMs507Specdb::CMs508Specdb::CMs923Specdb::CMs20878Specdb::CMs30021Specdb::CMs30687Specdb::CMs30860Specdb::CMs31110Specdb::CMs32285Specdb::CMs37395Specdb::CMs146150Specdb::CMs1056496Specdb::CMs1056497Specdb::CMs1056499Specdb::MsMs472Specdb::MsMs473Specdb::MsMs474Specdb::MsMs3885Specdb::MsMs3886Specdb::MsMs3887Specdb::MsMs3888Specdb::MsMs3889Specdb::MsMs3890Specdb::MsMs3891Specdb::MsMs3892Specdb::MsMs7130Specdb::MsMs7131Specdb::MsMs7132Specdb::MsMs13802Specdb::MsMs13803Specdb::MsMs13804Specdb::MsMs438428Specdb::MsMs438429Specdb::MsMs438430Specdb::MsMs446941Specdb::MsMs446942Specdb::MsMs446943Specdb::MsMs446944Specdb::MsMs446945AnatidaeType 1specificAnatidae8830BeefaloType 1specificBos taurus X Bison bison297284BisonType 1specificBison bison9901BuffaloType 1specificBubalus bubalis89462Cattle (Beef, Veal)Type 1specificBos taurus9913ChickenType 1specificGallus gallus9031Columbidae (Dove, Pigeon)Type 1specificColumbidae8930DeerType 1specificCervidae9850Domestic goatType 1specificCapra aegagrus hircus9925Domestic pigType 1specificSus scrofa domestica9825ElkType 1specificCervus canadensis1574408EmuType 1specificDromaius novaehollandiae8790European rabbitType 1specificOryctolagus9984Greylag gooseType 1specificAnser anser8843Guinea henType 1specificNumida meleagris8996HorseType 1specificEquus caballus9796Mallard duckType 1specificAnas platyrhynchos8839Mountain hareType 1specificLepus timidus62621Mule deerType 1specificOdocoileus9871OstrichType 1specificStruthio camelus8801PeanutType 1specificArachis hypogaea3818PheasantType 1specificPhasianus colchicus9054QuailType 1specificPhasianidae9005RabbitType 1specificLeporidae9979Rock ptarmiganType 1specificLagopus muta64668Sheep (Mutton, Lamb)Type 1specificOvis aries9940SquabType 1specificColumba8931TurkeyType 1specificMeleagris gallopavo9103Velvet duckType 1specificMelanitta fusca371864Wild boarType 1specificSus scrofa9823