1.02011-09-21 00:05:41 UTC2015-07-21 06:56:54 UTCFDB02194816-Oxoandrostenediol16-Oxoandrostenediol is a naturally occurring androgenic steroid hormone generated by the adrenal glands. It has been found in the urine of newborn infants. Secretion of this steroid is suppressed by dexamethasone. Levels of this hormone are almost absent by 5 months of age. ((Steroids (1964), 3(1), 77-83.) )
16-Oxoandrostenediol is a natural hormone with androgenic activity and that two potent antiandrogens: hydroxyflutamide (Eulexin) and bicalutamide (Casodex). [HMDB](3b,17b)-3b,17b-Dihydroxyandrost-5-en-16-one16-Oxoandrostenediol3b,17b-dihydroxy-Androst-5-en-16-one3b,17b-Dihydroxyandrost-5-en-16-one3beta,17beta-dihydroxy-Androst-5-en-16-one5-Androsten-3b,17b-diol-16-oneAndrost-5-ene-3b,17b-diol-16-oneC19H28O3304.4238304.203844762(2R,5S,14R,15S)-5,14-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-en-13-one5-androsten-3b,17b-diol-16-one1159-66-6C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34C)C1CC(=O)[C@@H]2OInChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(21)17(19)22/h3,12-15,17,20,22H,4-10H2,1-2H3/t12-,13?,14?,15?,17-,18-,19-/m0/s1AKRBLZKRYPEVIK-IACDPKRHSA-N belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans.Androgens and derivativesOrganic compoundsLipids and lipid-like moleculesSteroids and steroid derivativesAndrostane steroidsAliphatic homopolycyclic compounds16-oxosteroids17-hydroxysteroids3-beta-hydroxy delta-5-steroids3-beta-hydroxysteroidsCyclic alcohols and derivativesCyclic ketonesDelta-5-steroidsHydrocarbon derivativesOrganic oxidesSecondary alcohols16-oxosteroid17-hydroxysteroid3-beta-hydroxy-delta-5-steroid3-beta-hydroxysteroid3-hydroxy-delta-5-steroid3-hydroxysteroidAlcoholAliphatic homopolycyclic compoundAndrogen-skeletonCarbonyl groupCyclic alcoholCyclic ketoneDelta-5-steroidHydrocarbon derivativeHydroxysteroidKetoneOrganic oxideOrganic oxygen compoundOrganooxygen compoundOxosteroidSecondary alcoholSolidlogp2.39logs-3.39solubility1.25e-01 g/llogp2.13pka_strongest_acidic12.97pka_strongest_basic-1.4iupac(2R,5S,14R,15S)-5,14-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-en-13-oneaverage_mass304.4238mono_mass304.203844762smilesC[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34C)C1CC(=O)[C@@H]2OformulaC19H28O3inchiInChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(21)17(19)22/h3,12-15,17,20,22H,4-10H2,1-2H3/t12-,13?,14?,15?,17-,18-,19-/m0/s1inchikeyAKRBLZKRYPEVIK-IACDPKRHSA-Npolar_surface_area57.53refractivity85.95polarizability34.66rotatable_bond_count0acceptor_count3donor_count2physiological_charge0formal_charge0Specdb::CMs18927Specdb::CMs37430Specdb::CMs137408Specdb::CMs145142Specdb::CMs1058408Specdb::CMs1058410Specdb::CMs1058412Specdb::CMs1058414Specdb::CMs1058416Specdb::CMs1058418Specdb::CMs1058420Specdb::CMs1058422Specdb::CMs1058424Specdb::CMs1058427Specdb::CMs1058429Specdb::CMs1058431Specdb::CMs1058433Specdb::CMs1058435Specdb::CMs1058437Specdb::CMs1058439Specdb::CMs1058441Specdb::MsMs25241Specdb::MsMs25242Specdb::MsMs25243Specdb::MsMs31799Specdb::MsMs31800Specdb::MsMs31801Specdb::MsMs3058483Specdb::MsMs3058484Specdb::MsMs3058485Specdb::MsMs3108151Specdb::MsMs3108152Specdb::MsMs3108153HMDB00322AnatidaeType 1specificAnatidae8830BeefaloType 1specificBos taurus X Bison bison297284BisonType 1specificBison bison9901BuffaloType 1specificBubalus bubalis89462Cattle (Beef, Veal)Type 1specificBos taurus9913ChickenType 1specificGallus gallus9031Columbidae (Dove, Pigeon)Type 1specificColumbidae8930DeerType 1specificCervidae9850Domestic goatType 1specificCapra aegagrus hircus9925Domestic pigType 1specificSus scrofa domestica9825ElkType 1specificCervus canadensis1574408EmuType 1specificDromaius novaehollandiae8790European rabbitType 1specificOryctolagus9984Greylag gooseType 1specificAnser anser8843Guinea henType 1specificNumida meleagris8996HorseType 1specificEquus caballus9796Mallard duckType 1specificAnas platyrhynchos8839Mountain hareType 1specificLepus timidus62621Mule deerType 1specificOdocoileus9871OstrichType 1specificStruthio camelus8801PheasantType 1specificPhasianus colchicus9054QuailType 1specificPhasianidae9005RabbitType 1specificLeporidae9979Rock ptarmiganType 1specificLagopus muta64668Sheep (Mutton, Lamb)Type 1specificOvis aries9940SquabType 1specificColumba8931TurkeyType 1specificMeleagris gallopavo9103Velvet duckType 1specificMelanitta fusca371864Wild boarType 1specificSus scrofa9823