1.02011-09-21 00:07:36 UTC2015-10-09 22:30:25 UTCFDB022048(S)-3-Hydroxybutyric acid(S)-3-Hydroxybutyric acid is a normal human metabolite, that has been found elevated in geriatric patients remitting from depression. (PMID 17048218)
3-Hydroxybutyric acid is a ketone body. Like the other ketone bodies (acetoacetate and acetone), levels of 3-Hydroxybutyric acid are raised in ketosis. In humans, 3-Hydroxybutyric acid is synthesized in the liver from acetyl-CoA, and can be used as an energy source by the brain when blood glucose is low. [HMDB](+)-3-Hydroxy-n-butyric acid(+)-3-Hydroxybutyrate(+)-3-Hydroxybutyric acid(3S)-3-hydroxy-Butanoate(3S)-3-hydroxy-Butanoic acid(3S)-3-Hydroxybutyrate(3S)-3-Hydroxybutyric acid(S)-3-hydroxy-2-methyl-Propanoate(S)-3-hydroxy-2-methyl-Propanoic acid(S)-3-hydroxy-Butanoate(S)-3-hydroxy-Butanoic acid(S)-3-hydroxybutanoate(S)-3-Hydroxybutanoic acid(S)-3-Hydroxybutyrate(S)-3HB(S)-b-Hydroxybutyrate(S)-b-Hydroxybutyric acid(S)-b-Hydroxyisobutyrate(S)-b-Hydroxyisobutyric acid(S)-beta-Hydroxybutyrate(S)-beta-Hydroxybutyric acid(S)-beta-Hydroxyisobutyrate(S)-beta-Hydroxyisobutyric acid(S)-β-hydroxybutyrate(S)-β-hydroxybutyric acidL-(+)-2-methyl-HydracrylateL-(+)-2-methyl-Hydracrylic acidL-(+)-3-HydroxybutyrateL-(+)-3-Hydroxybutyric acidL-(+)-b-HydroxyisobutyrateL-(+)-b-Hydroxyisobutyric acidL-(+)-beta-HydroxyisobutyrateL-(+)-beta-Hydroxyisobutyric acidL-3-HydroxybutyrateL-3-Hydroxybutyric acidL-beta-HydroxybutyrateC4H8O3104.1045104.047344122(3S)-3-hydroxybutanoic acidβ-hydroxybutyrate,l6168-83-8C[C@H](O)CC(O)=OInChI=1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7)/t3-/m0/s1WHBMMWSBFZVSSR-VKHMYHEASA-N belongs to the class of organic compounds known as beta hydroxy acids and derivatives. Beta hydroxy acids and derivatives are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom.Beta hydroxy acids and derivativesOrganic compoundsOrganic acids and derivativesHydroxy acids and derivativesBeta hydroxy acids and derivativesAliphatic acyclic compoundsCarbonyl compoundsCarboxylic acidsFatty acids and conjugatesHydrocarbon derivativesMonocarboxylic acids and derivativesOrganic oxidesSecondary alcoholsShort-chain hydroxy acids and derivativesAlcoholAliphatic acyclic compoundBeta-hydroxy acidCarbonyl groupCarboxylic acidCarboxylic acid derivativeFatty acidHydrocarbon derivativeMonocarboxylic acid or derivativesOrganic oxideOrganic oxygen compoundOrganooxygen compoundSecondary alcoholShort-chain hydroxy acid3-hydroxybutyric acidSolidlogp-0.50logs0.71solubility5.39e+02 g/llogp-0.39pka_strongest_acidic4.41pka_strongest_basic-2.6iupac(3S)-3-hydroxybutanoic acidaverage_mass104.1045mono_mass104.047344122smilesC[C@H](O)CC(O)=OformulaC4H8O3inchiInChI=1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7)/t3-/m0/s1inchikeyWHBMMWSBFZVSSR-VKHMYHEASA-Npolar_surface_area57.53refractivity23.46polarizability9.94rotatable_bond_count2acceptor_count3donor_count2physiological_charge-1formal_charge0Specdb::NmrTwoD1315Specdb::CMs17759Specdb::CMs37538Specdb::CMs168615Specdb::CMs1062746Specdb::CMs1062748Specdb::CMs1062749Specdb::CMs1062751Specdb::CMs1062753Specdb::NmrOneD1371Specdb::NmrOneD143890Specdb::NmrOneD143891Specdb::NmrOneD143892Specdb::NmrOneD143893Specdb::NmrOneD143894Specdb::NmrOneD143895Specdb::NmrOneD143896Specdb::NmrOneD143897Specdb::NmrOneD143898Specdb::NmrOneD143899Specdb::NmrOneD143900Specdb::NmrOneD143901Specdb::NmrOneD143902Specdb::NmrOneD143903Specdb::NmrOneD143904Specdb::NmrOneD143905Specdb::NmrOneD143906Specdb::NmrOneD143907Specdb::NmrOneD143908Specdb::NmrOneD143909Specdb::MsMs644Specdb::MsMs645Specdb::MsMs646Specdb::MsMs305344Specdb::MsMs305345Specdb::MsMs305346Specdb::MsMs348736Specdb::MsMs348737Specdb::MsMs348738Specdb::MsMs2819199Specdb::MsMs2819200Specdb::MsMs2819201Specdb::MsMs2890537Specdb::MsMs2890538Specdb::MsMs2890539HMDB00442172903HL#<Reference:0x0000555675eb05c0>#<Reference:0x0000555675eb03e0>#<Reference:0x0000555675eb0228>#<Reference:0x0000555675eb0048>#<Reference:0x0000555675eafe40>#<Reference:0x0000555675eafc88>#<Reference:0x0000555675eafad0>#<Reference:0x0000555675eaf918>#<Reference:0x0000555675eaf760>#<Reference:0x0000555675eaf5a8>#<Reference:0x0000555675eaf3f0>#<Reference:0x0000555675eaf238>#<Reference:0x0000555675eaf080>#<Reference:0x0000555675eaeec8>AnatidaeType 1specificAnatidae8830BeefaloType 1specificBos taurus X Bison bison297284BisonType 1specificBison bison9901BuffaloType 1specificBubalus bubalis89462Cattle (Beef, Veal)Type 1specificBos taurus9913ChickenType 1specificGallus gallus9031Columbidae (Dove, Pigeon)Type 1specificColumbidae8930DeerType 1specificCervidae9850Domestic goatType 1specificCapra aegagrus hircus9925Domestic pigType 1specificSus scrofa domestica9825ElkType 1specificCervus canadensis1574408EmuType 1specificDromaius novaehollandiae8790European rabbitType 1specificOryctolagus9984Greylag gooseType 1specificAnser anser8843Guinea henType 1specificNumida meleagris8996HorseType 1specificEquus caballus9796Mallard duckType 1specificAnas platyrhynchos8839Mountain hareType 1specificLepus timidus62621Mule deerType 1specificOdocoileus9871OstrichType 1specificStruthio camelus8801PheasantType 1specificPhasianus colchicus9054QuailType 1specificPhasianidae9005RabbitType 1specificLeporidae9979Rock ptarmiganType 1specificLagopus muta64668Sheep (Mutton, Lamb)Type 1specificOvis aries9940SquabType 1specificColumba8931TurkeyType 1specificMeleagris gallopavo9103Velvet duckType 1specificMelanitta fusca371864Wild boarType 1specificSus scrofa9823