1.0 2011-09-21 00:11:52 UTC 2025-11-19 02:41:23 UTC FDB022307 Androstanedione Androstanedione is a steroid metabolite and a procursor of both testosterone and estrone. It is a product of enzyme 3alpha-hydroxysteroid dehydrogenase [EC 1.1.1.50] in pathway Androgen and estrogen metabolism (KEGG). [HMDB] (5a)-Androstane-3,17-dione 5-alpha-androstane-3,17-dione 5a-Androsta-3,17-dione 5a-Androstan-3,17-dione 5a-Androstane-3, 17-dione 5a-Androstane-3,17-dione 5a-Androstanedione 5alpha-Androstane-3,17-dione 5α-androstane-3,17-dione androstane-3,17-dione Androstane-3,7-dione Androstanedione C19H28O2 288.4244 288.20893014 (1S,2S,7S,10R,11S,15S)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane-5,14-dione (1S,2S,7S,10R,11S,15S)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane-5,14-dione 846-46-8 [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-16H,3-11H2,1-2H3/t12-,14-,15-,16-,18-,19-/m0/s1 RAJWOBJTTGJROA-WZNAKSSCSA-N belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. Androgens and derivatives Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Androstane steroids Aliphatic homopolycyclic compounds 17-oxosteroids 3-oxo-5-alpha-steroids Cyclic ketones Hydrocarbon derivatives Organic oxides 17-oxosteroid 3-oxo-5-alpha-steroid 3-oxosteroid Aliphatic homopolycyclic compound Androgen-skeleton Carbonyl group Cyclic ketone Hydrocarbon derivative Ketone Organic oxide Organic oxygen compound Organooxygen compound Oxosteroid C19 steroids (androgens) and derivatives androstane-3,17-dione Solid logp 3.40 ALOGPS logs -4.59 ALOGPS solubility 7.39e-03 g/l ALOGPS logp 3.97 ChemAxon pka_strongest_acidic 19.78 ChemAxon pka_strongest_basic -7.1 ChemAxon iupac (1S,2S,7S,10R,11S,15S)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane-5,14-dione ChemAxon average_mass 288.4244 ChemAxon mono_mass 288.20893014 ChemAxon smiles [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C ChemAxon formula C19H28O2 ChemAxon inchi InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-16H,3-11H2,1-2H3/t12-,14-,15-,16-,18-,19-/m0/s1 ChemAxon inchikey RAJWOBJTTGJROA-WZNAKSSCSA-N ChemAxon polar_surface_area 34.14 ChemAxon refractivity 82.78 ChemAxon polarizability 33.83 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::NmrOneD 1592 Specdb::NmrTwoD 1533 Specdb::CMs 2111 Specdb::CMs 11468 Specdb::CMs 29862 Specdb::CMs 31258 Specdb::CMs 170076 Specdb::MsMs 1274 Specdb::MsMs 1275 Specdb::MsMs 1276 Specdb::MsMs 247581 Specdb::MsMs 247582 Specdb::MsMs 247583 Specdb::MsMs 267522 Specdb::MsMs 267523 Specdb::MsMs 267524 Specdb::MsMs 439866 Specdb::MsMs 450090 Specdb::MsMs 450091 Specdb::MsMs 2810810 Specdb::MsMs 2810811 Specdb::MsMs 2810812 Specdb::MsMs 2895595 Specdb::MsMs 2895596 Specdb::MsMs 2895597 HMDB00899 15994 5SD #<Reference:0x000055ce328999b8> #<Reference:0x000055ce328992d8> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 3-oxo-5-alpha-steroid 4-dehydrogenase 1 P18405 SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 2 P31213 SRD5A2 3-oxo-5-beta-steroid 4-dehydrogenase P51857 AKR1D1 Polyprenol reductase Q9H8P0 SRD5A3