1.02011-09-21 00:15:21 UTC2015-07-21 06:57:15 UTCFDB022524Glyceric acid 1,3-biphosphate1,3-Bisphosphogylcerate (1,3BPG), also known as PGAP, is a 3-carbon organic molecule present in most, if not all living creatures. It primarily exists as a metabolic intermediate in glycolysis during respiration.
1,3BPG have been recognized as regulatory signal implicated in the control of metabolism, oxygen affinity of red cells and other cellular functions. 1,3BPG concentration in erythrocytes changes in a number of pathological conditions, such as Inherited Phosphoglycerate kinase deficiency in erythrocytes (involved in the synthesis and breakdown of 1,3 BPG). (PMID 3555887)
1,3-bisphosphoglycerate is the anion form of bisphosphoglyceric acid. It is phosphorylated at the number 1 and 3 carbons. The result of this phosphorylation gives 1,3BPG important biological properties such as the ability to phosphorylate ADP to form the energy storage molecule ATP.(wikipedia) [HMDB]1,3-Bioglycerate1,3-Bioglyceric acid1,3-Biphosphoglycerate1,3-Biphosphoglyceric acid1,3-Bis-oglycerate1,3-bis-phosphoglycerate1,3-Bisoglycerate1,3-Bisphosphoglycerate1,3-Diateglycerate1,3-Dioglycerate1,3-diphosphateglycerate1,3-Diphosphoglycerate13-DPG2-Hydroxy-3-(onooxy)-propanoate2-Hydroxy-3-(onooxy)-propanoic acid2-Hydroxy-3-(onooxy)-propanoic acid 1-anhydride with orate2-Hydroxy-3-(onooxy)-propanoic acid 1-anhydride with oric acid2-hydroxy-3-(phosphonooxy)-Propanoate2-hydroxy-3-(phosphonooxy)-Propanoic acid2-hydroxy-3-(phosphonooxy)-Propanoic acid 1-anhydride with phosphorate2-hydroxy-3-(phosphonooxy)-Propanoic acid 1-anhydride with phosphoric acid3-O-D-Glyceroyl ate3-O-D-Glyceroyl-ate3-Oglyceroyl ate3-Oglyceroyl-ate3-Oglyceroyl-P3-P-glyceroyl-P3-Phospho-D-glyceroyl phosphate3-phospho-D-glyceroyl-phosphate3-Phosphoglyceroyl phosphate3-phosphoglyceroyl-P3-phosphoglyceroyl-phosphateDPGGlycerate 1,3-biateGlycerate 1,3-BiphosphateGlycerate 1,3-bisateglycerate 1,3-bisphosphateGlycerate 1,3-diateglycerate 1,3-diphosphateGlyceric acid 1,3-biateGlyceric acid 1,3-biphosphateGlyceric acid 1,3-biphosphic acidOglyceroyl-PP-glyceroyl-PPhosphoglyceroyl-PC3H8O10P2266.0371265.9592695{[2-hydroxy-3-(phosphonooxy)propanoyl]oxy}phosphonic acid1,3-bisphosphoglycerate1981-49-3OC(COP(O)(O)=O)C(=O)OP(O)(O)=OInChI=1S/C3H8O10P2/c4-2(1-12-14(6,7)8)3(5)13-15(9,10)11/h2,4H,1H2,(H2,6,7,8)(H2,9,10,11)LJQLQCAXBUHEAZ-UHFFFAOYSA-N belongs to the class of organic compounds known as acyl monophosphates. These are organic compounds containing a monophosphate linked to an acyl group. They have the general structure R-CO-P(O)(O)OH, R=H or organyl.Acyl monophosphatesOrganic compoundsOrganic acids and derivativesOrganic phosphoric acids and derivativesPhosphate estersAliphatic acyclic compoundsCarbonyl compoundsCarboxylic acid saltsHydrocarbon derivativesMonoalkyl phosphatesMonocarboxylic acids and derivativesMonosaccharidesOrganic oxidesOrganic saltsSecondary alcoholsSugar acids and derivativesAcyl monophosphateAlcoholAliphatic acyclic compoundAlkyl phosphateCarbonyl groupCarboxylic acid derivativeCarboxylic acid saltGlyceric_acidHydrocarbon derivativeMonoalkyl phosphateMonocarboxylic acid or derivativesMonosaccharideOrganic oxideOrganic oxygen compoundOrganic saltOrganooxygen compoundSecondary alcoholSolidlogp-1.14logs-1.44solubility9.64e+00 g/llogp-2.3pka_strongest_acidic1.01pka_strongest_basic-4.2iupac{[2-hydroxy-3-(phosphonooxy)propanoyl]oxy}phosphonic acidaverage_mass266.0371mono_mass265.9592695smilesOC(COP(O)(O)=O)C(=O)OP(O)(O)=OformulaC3H8O10P2inchiInChI=1S/C3H8O10P2/c4-2(1-12-14(6,7)8)3(5)13-15(9,10)11/h2,4H,1H2,(H2,6,7,8)(H2,9,10,11)inchikeyLJQLQCAXBUHEAZ-UHFFFAOYSA-Npolar_surface_area170.82refractivity42.42polarizability18.04rotatable_bond_count6acceptor_count8donor_count5physiological_charge-4formal_charge0GluconeogenesisSMP00128map00010Glycerol Phosphate ShuttleSMP00124GlycolysisSMP00040map00010Mitochondrial Electron Transport ChainSMP00355map00190Specdb::CMs3117Specdb::CMs38003Specdb::NmrOneD246608Specdb::NmrOneD246609Specdb::NmrOneD246610Specdb::NmrOneD246611Specdb::NmrOneD246612Specdb::NmrOneD246613Specdb::NmrOneD246614Specdb::NmrOneD246615Specdb::NmrOneD246616Specdb::NmrOneD246617Specdb::NmrOneD246618Specdb::NmrOneD246619Specdb::NmrOneD246620Specdb::NmrOneD246621Specdb::NmrOneD246622Specdb::NmrOneD246623Specdb::NmrOneD246624Specdb::NmrOneD246625Specdb::NmrOneD246626Specdb::NmrOneD246627Specdb::MsMs25007Specdb::MsMs25008Specdb::MsMs25009Specdb::MsMs31565Specdb::MsMs31566Specdb::MsMs31567HMDB01270#<Reference:0x00005556736f56c0>#<Reference:0x00005556736f53f0>#<Reference:0x00005556736f5120>#<Reference:0x00005556736f4e78>#<Reference:0x00005556736f4c20>#<Reference:0x00005556736f49a0>#<Reference:0x00005556736f4720>#<Reference:0x00005556736f4400>#<Reference:0x00005556736f41a8>#<Reference:0x0000555673703d38>#<Reference:0x0000555673703888>Acylphosphatase-1P07311ACYP1Acylphosphatase-2P14621ACYP2Bisphosphoglycerate mutaseP07738BPGMGlucose 1,6-bisphosphate synthaseQ6PCE3PGM2L1Phosphoglycerate kinase 1P00558PGK1Phosphoglycerate kinase 2P07205PGK2Phosphoglycerate mutase 1P18669PGAM1Phosphoglycerate mutase 2P15259PGAM2Probable phosphoglycerate mutase 4Q8N0Y7PGAM4