1.02011-09-21 00:19:08 UTC2018-05-28 18:33:55 UTCFDB022757PhenylpropanolaminePhenylpropanolamine is a sympathomimetic that acts mainly by causing release of norepinephrine but also has direct agonist activity at some adrenergic receptors. It is most commonly used as a nasal vasoconstrictor and an appetite depressant. -- Pubchem [HMDB]D-NorephedrineDL-NorephedrineDL-PhenylpropanolamineHydriatinel-NOREPHEDRINEL-Phenyl PropanolamineMucoramaNobeseNorephedrineObestatPhenylpropanolaminePrestwick_388PropadrineC9H13NO151.2056151.099714043(1S,2R)-2-amino-1-phenylpropan-1-olphenylpropanolamine14838-15-4C[C@@H](N)[C@@H](O)C1=CC=CC=C1InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m1/s1DLNKOYKMWOXYQA-VXNVDRBHSA-N belongs to the class of organic compounds known as phenylpropanes. These are organic compounds containing a phenylpropane moiety.PhenylpropanesOrganic compoundsBenzenoidsBenzene and substituted derivativesPhenylpropanesAromatic homomonocyclic compounds1,2-aminoalcoholsAralkylaminesAromatic alcoholsHydrocarbon derivativesMonoalkylaminesOrganopnictogen compoundsSecondary alcohols1,2-aminoalcoholAlcoholAmineAralkylamineAromatic alcoholAromatic homomonocyclic compoundHydrocarbon derivativeOrganic nitrogen compoundOrganic oxygen compoundOrganonitrogen compoundOrganooxygen compoundOrganopnictogen compoundPhenylpropanePrimary aliphatic aminePrimary amineSecondary alcoholamphetaminesSolidlogp0.57logs-0.87solubility2.06e+01 g/llogp0.89pka_strongest_acidic13.9pka_strongest_basic9.37iupac(1S,2R)-2-amino-1-phenylpropan-1-olaverage_mass151.2056mono_mass151.099714043smilesC[C@@H](N)[C@@H](O)C1=CC=CC=C1formulaC9H13NOinchiInChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m1/s1inchikeyDLNKOYKMWOXYQA-VXNVDRBHSA-Npolar_surface_area46.25refractivity44.91polarizability16.98rotatable_bond_count2acceptor_count2donor_count2physiological_charge1formal_charge0Specdb::NmrTwoD1760Specdb::MsIr1477Specdb::MsIr1478Specdb::MsIr1479Specdb::CMs8132Specdb::CMs38196Specdb::CMs136062Specdb::CMs143796Specdb::NmrOneD1820Specdb::NmrOneD102698Specdb::NmrOneD102699Specdb::NmrOneD102700Specdb::NmrOneD102701Specdb::NmrOneD102702Specdb::NmrOneD102703Specdb::NmrOneD102704Specdb::NmrOneD102705Specdb::NmrOneD102706Specdb::NmrOneD102707Specdb::NmrOneD102708Specdb::NmrOneD102709Specdb::NmrOneD102710Specdb::NmrOneD102711Specdb::NmrOneD102712Specdb::NmrOneD102713Specdb::NmrOneD102714Specdb::NmrOneD102715Specdb::NmrOneD102716Specdb::NmrOneD102717Specdb::MsMs1899Specdb::MsMs1900Specdb::MsMs1901Specdb::MsMs257943Specdb::MsMs257944Specdb::MsMs257945Specdb::MsMs277881Specdb::MsMs277882Specdb::MsMs277883Specdb::MsMs441092Specdb::MsMs449907Specdb::MsMs2238358Specdb::MsMs2370680Specdb::MsMs2370681Specdb::MsMs2370682Specdb::MsMs2568493Specdb::MsMs2568494Specdb::MsMs2568495HMDB01942#<Reference:0x0000555673701628>#<Reference:0x0000555673701358>#<Reference:0x0000555673700d90>#<Reference:0x0000555673700958>#<Reference:0x0000555673700700>#<Reference:0x00005556737004a8>Alpha-2A adrenergic receptorP08913ADRA2A