1.0 2011-09-21 00:19:49 UTC 2025-11-19 02:42:32 UTC FDB022801 Glycineamideribotide Glycinamidoribotide conversion to N-formylglycinamide ribonucleotide is the third reaction of the de novo purine biosynthesis, a reaction catalyzed by the enzyme Glycinamide ribonucleotide transformylase (EC 2.1.2.2), with concomitant conversion of 10-formyltetrahydrofolate to tetrahydrofolate. (PMID: 9143358). Glycineamideribotide formation is stimulated by Luteinizing hormone (LH) and Chorionic gonadotropin (HCG) via activation of Glc-6-P-dehydrogenase (EC 1.1.1.49). (PMID: 4366083) [HMDB] 5'-Oribosyl-glycineamide 5'-Oribosylglycinamide 5'-Oribosylglycineamide 5'-Phosphoribosyl-glycineamide 5'-Phosphoribosylglycinamide 5'-Phosphoribosylglycineamide GAR Glycinamide ribonucleotide Glycineamide ribonucleotide N-Glycyl-5-O-ONO-D-ribofuranosylamine N-glycyl-5-O-phosphono-D-ribofuranosylamine N(1)-(5-O-D-Ribosyl)glycinamide N(1)-(5-phospho-D-ribosyl)glycinamide N1-(5-O-D-Ribosyl)glycinamide N1-(5-phospho-D-ribosyl)glycinamide C7H15N2O8P 286.1764 286.056601978 {[(2R,3S,4R,5R)-5-(2-aminoacetamido)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid glycineamide ribonucleotide 10074-18-7 NCC(=O)N[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C7H15N2O8P/c8-1-4(10)9-7-6(12)5(11)3(17-7)2-16-18(13,14)15/h3,5-7,11-12H,1-2,8H2,(H,9,10)(H2,13,14,15)/t3-,5-,6-,7-/m1/s1 OBQMLSFOUZUIOB-SHUUEZRQSA-N belongs to the class of organic compounds known as glycinamide ribonucleotides. Glycinamide ribonucleotides are compounds in which the amide N atom of glycineamide is linked to the C-1 of a ribosyl (or deoxyribosyl) moiety. Nucleotides have a phosphate group linked to the C5 carbon of the ribose (or deoxyribose) moiety. Glycinamide ribonucleotides Organic compounds Nucleosides, nucleotides, and analogues Glycinamide ribonucleotides Aliphatic heteromonocyclic compounds 1,2-diols Alpha amino acid amides Carbonyl compounds Hydrocarbon derivatives Monoalkyl phosphates Monoalkylamines Monosaccharide phosphates Organic oxides Organopnictogen compounds Oxacyclic compounds Pentose phosphates Secondary alcohols Secondary carboxylic acid amides Tetrahydrofurans 1,2-diol Alcohol Aliphatic heteromonocyclic compound Alkyl phosphate Alpha-amino acid amide Alpha-amino acid or derivatives Amine Amino acid or derivatives Carbonyl group Carboxamide group Carboxylic acid derivative Glycinamide-ribonucleotide Hydrocarbon derivative Monoalkyl phosphate Monosaccharide Monosaccharide phosphate Organic nitrogen compound Organic oxide Organic oxygen compound Organic phosphoric acid derivative Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Pentose monosaccharide Pentose phosphate Pentose-5-phosphate Phosphoric acid ester Primary aliphatic amine Primary amine Secondary alcohol Secondary carboxylic acid amide Tetrahydrofuran Solid logp -2.40 ALOGPS logs -1.29 ALOGPS solubility 1.46e+01 g/l ALOGPS logp -4.7 ChemAxon pka_strongest_acidic 1.23 ChemAxon pka_strongest_basic 8.14 ChemAxon iupac {[(2R,3S,4R,5R)-5-(2-aminoacetamido)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid ChemAxon average_mass 286.1764 ChemAxon mono_mass 286.056601978 ChemAxon smiles NCC(=O)N[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O ChemAxon formula C7H15N2O8P ChemAxon inchi InChI=1S/C7H15N2O8P/c8-1-4(10)9-7-6(12)5(11)3(17-7)2-16-18(13,14)15/h3,5-7,11-12H,1-2,8H2,(H,9,10)(H2,13,14,15)/t3-,5-,6-,7-/m1/s1 ChemAxon inchikey OBQMLSFOUZUIOB-SHUUEZRQSA-N ChemAxon polar_surface_area 171.57 ChemAxon refractivity 55.29 ChemAxon polarizability 23.68 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 8 ChemAxon donor_count 6 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Purine Metabolism SMP00050 map00230 Specdb::NmrOneD 148780 Specdb::NmrOneD 148781 Specdb::NmrOneD 148782 Specdb::NmrOneD 148783 Specdb::NmrOneD 148784 Specdb::NmrOneD 148785 Specdb::NmrOneD 148786 Specdb::NmrOneD 148787 Specdb::NmrOneD 148788 Specdb::NmrOneD 148789 Specdb::NmrOneD 148790 Specdb::NmrOneD 148791 Specdb::NmrOneD 148792 Specdb::NmrOneD 148793 Specdb::NmrOneD 148794 Specdb::NmrOneD 148795 Specdb::NmrOneD 148796 Specdb::NmrOneD 148797 Specdb::NmrOneD 148798 Specdb::NmrOneD 148799 Specdb::CMs 2935 Specdb::CMs 38227 Specdb::CMs 148298 Specdb::MsMs 29540 Specdb::MsMs 29541 Specdb::MsMs 29542 Specdb::MsMs 36098 Specdb::MsMs 36099 Specdb::MsMs 36100 Specdb::MsMs 2703398 Specdb::MsMs 2703399 Specdb::MsMs 2703400 Specdb::MsMs 3002740 Specdb::MsMs 3002741 Specdb::MsMs 3002742 HMDB02022 18349 #<Reference:0x00007f093c1ad7f8> #<Reference:0x00007f093c1ad5a0> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 Trifunctional purine biosynthetic protein adenosine-3 P22102 GART