1.0 2011-09-21 00:21:10 UTC 2015-07-21 06:57:24 UTC FDB022889 Peroxynitrite Peroxynitrite is a potent oxidant synthesized by the cell during its normal metabolism. The peroxynitrite anion (ONOO-) is a reactive species produced in the reaction between the superoxide anion (O2*-) and nitric oxide (*NO). Peroxynitrite (ONOO-) is a strong oxidation and nitration agent, which damages DNA, proteins and other cellular structures. ONOO- is involved in several pathological conditions such as inflammation, arteriosclerosis, and neurodegenerative and cardiovascular disorders. ONOO- inhibits different steps of blood platelet activation and causes the depletion of platelet thiols. (PMID 15647782) [HMDB] (-)Oxoperoxonitrate (1-)oxidoperoxidonitrate [NO(OO)](-) Azoperoxoite Pernitrite Peroxonitrite Peroxynitrate Peroxynitrite Peroxynitrosyl (NO3) NO3 62.0049 61.987817871 (nitrosooxy)olate peroxynitrite 19059-14-4 [O-]ON=O InChI=1S/HNO3/c2-1-4-3/h3H/p-1 CMFNMSMUKZHDEY-UHFFFAOYSA-M belongs to the class of inorganic compounds known as non-metal peroxynitrites. These are inorganic non-metallic compounds containing a peroxynitrite as its largest oxoanion. Non-metal peroxynitrites Inorganic compounds Homogeneous non-metal compounds Non-metal oxoanionic compounds Non-metal peroxynitrites Inorganic nitrites Inorganic oxides Inorganic nitrite Inorganic oxide Non-metal peroxynitrite an anion nitrogen oxoanion reactive nitrogen species reactive oxygen species Solid logp 0.32 ChemAxon pka_strongest_acidic 6.55 ChemAxon pka_strongest_basic -5.5 ChemAxon iupac (nitrosooxy)olate ChemAxon average_mass 62.0049 ChemAxon mono_mass 61.987817871 ChemAxon smiles [O-]ON=O ChemAxon formula NO3 ChemAxon inchi InChI=1S/HNO3/c2-1-4-3/h3H/p-1 ChemAxon inchikey CMFNMSMUKZHDEY-UHFFFAOYSA-M ChemAxon polar_surface_area 61.72 ChemAxon refractivity 8.95 ChemAxon polarizability 3.33 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 3 ChemAxon donor_count 0 ChemAxon physiological_charge -1 ChemAxon formal_charge -1 ChemAxon Specdb::MsMs 347026 Specdb::MsMs 347027 Specdb::MsMs 347028 HMDB02179 25941 #<Reference:0x000055ce30f9cc30> #<Reference:0x000055ce30f9ca78> #<Reference:0x000055ce30f9c870> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823