1.02011-09-21 00:22:12 UTC2015-07-21 06:57:26 UTCFDB022947N-AcetylcadaverineN-Acetylcadaverine is the acetylated form of the polyamine cadaverine. Cadaverine is produced by the breakdown of amino acids in living and dead organisms and is toxic in large doses. Cadaverine is largely responsible for the foul odor of putrefying flesh, but also contributes to the odor of such processes as bad breath and bacterial vaginosis. Cadaverine is also found in semen. Polyamines (and their acetylated forms) are known to be closely related with cell growth, cell proliferation, and synthesis of proteins and nucleic acids. Their concentrations are adjusted either by regulating the activity levels of the biosynthetic and catabolic reactions or by controlling the net direction of polyamine acetylation-deacetylation. In Alzheimer's disease (AD), the neurotoxic amyloid β-peptide is known to up-regulate polyamine metabolism by increasing ornithine decarboxylase activity and polyamine uptake by initiating free radical damage. Because of these findings, polyamines have been considered to play an important role in response to neurodegenerative conditions. Altered levels of polyamines have been found in tissue, hair and body fluids of patients with neuromuscular diseases and neurodegenerative conditions. (PMID: 17723614) [HMDB]AcetylcadaverineMonoacetyl cadaverineN-(5-aminopentyl)acetamideC7H16N2O144.2147144.126263144N-(5-aminopentyl)acetamideN-acetylcadaverine32343-73-0CC(=O)NCCCCCNInChI=1S/C7H16N2O/c1-7(10)9-6-4-2-3-5-8/h2-6,8H2,1H3,(H,9,10)RMOIHHAKNOFHOE-UHFFFAOYSA-N belongs to the class of organic compounds known as acetamides. These are organic compounds with the general formula RNHC(=O)CH3, where R= organyl group.AcetamidesOrganic compoundsOrganic acids and derivativesCarboxylic acids and derivativesCarboxylic acid derivativesAliphatic acyclic compoundsAmino acids and derivativesCarbonyl compoundsHydrocarbon derivativesMonoalkylaminesOrganic oxidesOrganopnictogen compoundsSecondary carboxylic acid amidesAcetamideAliphatic acyclic compoundAmineAmino acid or derivativesCarbonyl groupHydrocarbon derivativeOrganic nitrogen compoundOrganic oxideOrganic oxygen compoundOrganonitrogen compoundOrganooxygen compoundOrganopnictogen compoundPrimary aliphatic aminePrimary amineSecondary carboxylic acid amideSolidlogp-0.40logs-0.78solubility2.37e+01 g/llogp-0.58pka_strongest_acidic16.53pka_strongest_basic10.21iupacN-(5-aminopentyl)acetamideaverage_mass144.2147mono_mass144.126263144smilesCC(=O)NCCCCCNformulaC7H16N2OinchiInChI=1S/C7H16N2O/c1-7(10)9-6-4-2-3-5-8/h2-6,8H2,1H3,(H,9,10)inchikeyRMOIHHAKNOFHOE-UHFFFAOYSA-Npolar_surface_area55.12refractivity41.42polarizability17.36rotatable_bond_count5acceptor_count2donor_count2physiological_charge1formal_charge0Specdb::CMs11182Specdb::CMs148905Specdb::MsIr1719Specdb::MsIr1720Specdb::MsIr1721Specdb::NmrOneD115978Specdb::NmrOneD115979Specdb::NmrOneD115980Specdb::NmrOneD115981Specdb::NmrOneD115982Specdb::NmrOneD115983Specdb::NmrOneD115984Specdb::NmrOneD115985Specdb::NmrOneD115986Specdb::NmrOneD115987Specdb::NmrOneD115988Specdb::NmrOneD115989Specdb::NmrOneD115990Specdb::NmrOneD115991Specdb::NmrOneD115992Specdb::NmrOneD115993Specdb::NmrOneD115994Specdb::NmrOneD115995Specdb::NmrOneD115996Specdb::NmrOneD115997Specdb::MsMs100776Specdb::MsMs100777Specdb::MsMs100778Specdb::MsMs166218Specdb::MsMs166219Specdb::MsMs166220Specdb::MsMs2840703Specdb::MsMs2840704Specdb::MsMs2840705Specdb::MsMs2865081Specdb::MsMs2865082Specdb::MsMs2865083HMDB02284#<Reference:0x0000555675ff0890>#<Reference:0x0000555675ff04d0>#<Reference:0x0000555675ff0318>AnatidaeType 1specificAnatidae8830BeefaloType 1specificBos taurus X Bison bison297284BisonType 1specificBison bison9901BuffaloType 1specificBubalus bubalis89462Cattle (Beef, Veal)Type 1specificBos taurus9913ChickenType 1specificGallus gallus9031Columbidae (Dove, Pigeon)Type 1specificColumbidae8930DeerType 1specificCervidae9850Domestic goatType 1specificCapra aegagrus hircus9925Domestic pigType 1specificSus scrofa domestica9825ElkType 1specificCervus canadensis1574408EmuType 1specificDromaius novaehollandiae8790European rabbitType 1specificOryctolagus9984Greylag gooseType 1specificAnser anser8843Guinea henType 1specificNumida meleagris8996HorseType 1specificEquus caballus9796Mallard duckType 1specificAnas platyrhynchos8839Mountain hareType 1specificLepus timidus62621Mule deerType 1specificOdocoileus9871OstrichType 1specificStruthio camelus8801PheasantType 1specificPhasianus colchicus9054QuailType 1specificPhasianidae9005RabbitType 1specificLeporidae9979Rock ptarmiganType 1specificLagopus muta64668Sheep (Mutton, Lamb)Type 1specificOvis aries9940SquabType 1specificColumba8931TurkeyType 1specificMeleagris gallopavo9103Velvet duckType 1specificMelanitta fusca371864Wild boarType 1specificSus scrofa9823