1.02011-09-21 00:25:51 UTC2015-10-09 22:33:06 UTCFDB0231813,5-Diiodo-L-tyrosineA product from the iodination of monoiodotyrosine. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other monoiodotyrosine or diiodotyrosine residues to form T4 or T3 thyroid hormones (thyroxine and triiodothyronine). [HMDB](2S)-2-amino-3-(4-Hydroxy-3,5-diiodophenyl)propanoate(2S)-2-amino-3-(4-Hydroxy-3,5-diiodophenyl)propanoic acid3,5-Diiodotyrocine3,5-Diiodotyrosine3,5-Iodo-L-tyrosine3,5-L-Diiodotyrosine4-Hydroxy-3,5-diiodophenylalanineDiiodotyrosineDiIYDITL-3,5-DiioDOTyrosineL-DiiodotyrosineC9H9I2NO3432.9816432.867179999(2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid3,5-diiodotyrosine300-39-0[H][C@](N)(CC1=CC(I)=C(O)C(I)=C1)C(O)=OInChI=1S/C9H9I2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)/t7-/m0/s1NYPYHUZRZVSYKL-ZETCQYMHSA-N belongs to the class of organic compounds known as tyrosine and derivatives. Tyrosine and derivatives are compounds containing tyrosine or a derivative thereof resulting from reaction of tyrosine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.Tyrosine and derivativesOrganic compoundsOrganic acids and derivativesCarboxylic acids and derivativesAmino acids, peptides, and analoguesAromatic homomonocyclic compoundsAmino acidsAmphetamines and derivativesAralkylaminesAryl iodidesCarbonyl compoundsCarboxylic acidsHydrocarbon derivativesIodobenzenesL-alpha-amino acidsMonoalkylaminesMonocarboxylic acids and derivativesO-iodophenolsOrganic oxidesOrganoiodidesOrganopnictogen compoundsPhenylalanine and derivativesPhenylpropanoic acids2-halophenol2-iodophenol3-phenylpropanoic-acidAlpha-amino acidAmineAmino acidAmphetamine or derivativesAralkylamineAromatic homomonocyclic compoundAryl halideAryl iodideBenzenoidCarbonyl groupCarboxylic acidHalobenzeneHydrocarbon derivativeIodobenzeneL-alpha-amino acidMonocarboxylic acid or derivativesMonocyclic benzene moietyOrganic nitrogen compoundOrganic oxideOrganic oxygen compoundOrganohalogen compoundOrganoiodideOrganonitrogen compoundOrganooxygen compoundOrganopnictogen compoundPhenolPhenylalanine or derivativesPrimary aliphatic aminePrimary amineTyrosine or derivativesL-tyrosine derivativeOther amino acidsdiiodotyrosinenon-proteinogenic L-alpha-amino acidSolidlogp-0.70logs-2.92solubility5.19e-01 g/llogp0.37pka_strongest_acidic0.48pka_strongest_basic9.45iupac(2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acidaverage_mass432.9816mono_mass432.867179999smiles[H][C@](N)(CC1=CC(I)=C(O)C(I)=C1)C(O)=OformulaC9H9I2NO3inchiInChI=1S/C9H9I2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)/t7-/m0/s1inchikeyNYPYHUZRZVSYKL-ZETCQYMHSA-Npolar_surface_area83.55refractivity73.82polarizability29.1rotatable_bond_count3acceptor_count4donor_count3physiological_charge0formal_charge0Tyrosine MetabolismSMP00006map00350Specdb::NmrTwoD1909Specdb::CMs2038Specdb::CMs8470Specdb::CMs31465Specdb::CMs38612Specdb::CMs172762Specdb::NmrOneD1974Specdb::NmrOneD10602Specdb::NmrOneD10603Specdb::NmrOneD10604Specdb::NmrOneD10605Specdb::NmrOneD10606Specdb::NmrOneD10607Specdb::NmrOneD10608Specdb::NmrOneD10609Specdb::NmrOneD10610Specdb::NmrOneD10611Specdb::NmrOneD10612Specdb::NmrOneD10613Specdb::NmrOneD10614Specdb::NmrOneD10615Specdb::NmrOneD10616Specdb::NmrOneD10617Specdb::NmrOneD10618Specdb::NmrOneD10619Specdb::NmrOneD10620Specdb::NmrOneD10621Specdb::MsMs6395Specdb::MsMs6396Specdb::MsMs6397Specdb::MsMs6398Specdb::MsMs6399Specdb::MsMs6400Specdb::MsMs6401Specdb::MsMs6402Specdb::MsMs6403Specdb::MsMs6404Specdb::MsMs259881Specdb::MsMs259882Specdb::MsMs259883Specdb::MsMs279819Specdb::MsMs279820Specdb::MsMs279821Specdb::MsMs374971Specdb::MsMs437554Specdb::MsMs437555Specdb::MsMs437556Specdb::MsMs437557Specdb::MsMs437558Specdb::MsMs446014Specdb::MsMs446015Specdb::MsMs446016HMDB0347415768TYI#<Reference:0x00005556764618e8>#<Reference:0x0000555676461730>#<Reference:0x0000555676461280>AnatidaeType 1specificAnatidae8830BeefaloType 1specificBos taurus X Bison bison297284BisonType 1specificBison bison9901BuffaloType 1specificBubalus bubalis89462Cattle (Beef, Veal)Type 1specificBos taurus9913ChickenType 1specificGallus gallus9031Columbidae (Dove, Pigeon)Type 1specificColumbidae8930DeerType 1specificCervidae9850Domestic goatType 1specificCapra aegagrus hircus9925Domestic pigType 1specificSus scrofa domestica9825ElkType 1specificCervus canadensis1574408EmuType 1specificDromaius novaehollandiae8790European rabbitType 1specificOryctolagus9984Greylag gooseType 1specificAnser anser8843Guinea henType 1specificNumida meleagris8996HorseType 1specificEquus caballus9796Mallard duckType 1specificAnas platyrhynchos8839Mountain hareType 1specificLepus timidus62621Mule deerType 1specificOdocoileus9871OstrichType 1specificStruthio camelus8801PheasantType 1specificPhasianus colchicus9054QuailType 1specificPhasianidae9005RabbitType 1specificLeporidae9979Rock ptarmiganType 1specificLagopus muta64668Sheep (Mutton, Lamb)Type 1specificOvis aries9940SquabType 1specificColumba8931TurkeyType 1specificMeleagris gallopavo9103Velvet duckType 1specificMelanitta fusca371864Wild boarType 1specificSus scrofa9823