1.02011-09-21 00:31:55 UTC2015-10-09 22:33:11 UTCFDB023581LansoprazoleLansoprazole is a proton pump inhibitor similar to omeprazole which prevents the stomach from producing acid. Lansoprazole's plasma elimination half-life is not proportional to the duration of the drug's effects (i.e. gastric acid suppression). The plasma elimination half-life is 1.5 hours or less, and the effects of the drug last for over 24 hours after it has been given for 5 days or more. [HMDB]AG 1749AgoptonAmarinAprazolBamaliteBlasonKetianLancidLanfastLanprotonLansopepLansophedLansoprazolLansoprazoleLansoprazolumLansoxLanstonLanzLanzoLanzolLanzopralLanzorLanzulLaprazLasoprolLimpidexMesactolMonolitumOgastroOpirenPrevacidC16H14F3N3O2S369.361369.0758820122-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazolelansoprazole103577-45-3CC1=C(OCC(F)(F)F)C=CN=C1CS(=O)C1=NC2=CC=CC=C2N1InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)MJIHNNLFOKEZEW-UHFFFAOYSA-N belongs to the class of organic compounds known as sulfinylbenzimidazoles. These are polycyclic aromatic compounds containing a sulfinyl group attached at the position 2 of a benzimidazole moiety.SulfinylbenzimidazolesOrganic compoundsOrganoheterocyclic compoundsBenzimidazolesSulfinylbenzimidazolesAromatic heteropolycyclic compoundsAlkyl aryl ethersAlkyl fluoridesAzacyclic compoundsBenzenoidsHeteroaromatic compoundsHydrocarbon derivativesImidazolesMethylpyridinesOrganic oxidesOrganofluoridesOrganonitrogen compoundsOrganopnictogen compoundsSulfinyl compoundsSulfoxidesAlkyl aryl etherAlkyl fluorideAlkyl halideAromatic heteropolycyclic compoundAzacycleAzoleBenzenoidEtherHeteroaromatic compoundHydrocarbon derivativeImidazoleMethylpyridineOrganic nitrogen compoundOrganic oxideOrganic oxygen compoundOrganofluorideOrganohalogen compoundOrganonitrogen compoundOrganooxygen compoundOrganopnictogen compoundOrganosulfur compoundPyridineSulfinyl compoundSulfinylbenzimidazoleSulfoxidebenzimidazolespyridinessulfoxideSolidlogp2.84logs-3.17solubility2.50e-01 g/llogp3.03pka_strongest_acidic9.35pka_strongest_basic4.16iupac2-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazoleaverage_mass369.361mono_mass369.075882012smilesCC1=C(OCC(F)(F)F)C=CN=C1CS(=O)C1=NC2=CC=CC=C2N1formulaC16H14F3N3O2SinchiInChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)inchikeyMJIHNNLFOKEZEW-UHFFFAOYSA-Npolar_surface_area67.87refractivity87.61polarizability34.59rotatable_bond_count6acceptor_count4donor_count1physiological_charge0formal_charge0Specdb::NmrOneD2017Specdb::NmrTwoD1952Specdb::CMs8360Specdb::CMs123605Specdb::CMs128682Specdb::CMs147849Specdb::MsMs436409Specdb::MsMs436410Specdb::MsMs436411Specdb::MsMs436412Specdb::MsMs436413Specdb::MsMs436414Specdb::MsMs436415Specdb::MsMs436416Specdb::MsMs436417Specdb::MsMs2229142Specdb::MsMs2230294Specdb::MsMs2234030Specdb::MsMs2236096Specdb::MsMs2237304Specdb::MsMs2240312Specdb::MsMs2240679Specdb::MsMs2241413Specdb::MsMs2439Specdb::MsMs2440Specdb::MsMs2441Specdb::MsMs374226Specdb::MsMs443794Specdb::MsMs443795Specdb::MsMs443796Specdb::MsMs443797HMDB05008#<Reference:0x0000555675ec7298>#<Reference:0x0000555675ec70e0>Potassium-transporting ATPase alpha chain 1P20648ATP4A