1.02011-09-21 00:32:18 UTC2015-10-09 22:33:06 UTCFDB023605CitalopramCitalopram is an antidepressant drug used to treat depression associated with mood disorders. It is also used on occasion in the treatment of body dysmorphic disorder and anxiety; Citalopram belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). It is sold under the brand-names Celexa (U.S., Forest Laboratories, Inc.), Cipramil, Seropram (Europe and Australia) and Ciazil (Australia); A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition; Citalopram is an antidepressant drug used to treat depression associated with mood disorders. It is also used on occasion in the treatment of body dysmorphic disorder and anxiety.
Citalopram belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). [HMDB]BonitrileCelexaCitadurCitalopram hydrobromideNitalapramC20H21FN2O324.3919324.1637915091-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrilerecital59729-33-8CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3WSEQXVZVJXJVFP-UHFFFAOYSA-N belongs to the class of organic compounds known as phenylbutylamines. Phenylbutylamines are compounds containing a phenylbutylamine moiety, which consists of a phenyl group substituted at the fourth carbon by an butan-1-amine.PhenylbutylaminesOrganic compoundsBenzenoidsBenzene and substituted derivativesPhenylbutylaminesAromatic heteropolycyclic compoundsAralkylaminesAryl fluoridesDialkyl ethersFluorobenzenesHydrocarbon derivativesIsocoumaransNitrilesOrganofluoridesOrganopnictogen compoundsOxacyclic compoundsTrialkylaminesAmineAralkylamineAromatic heteropolycyclic compoundAryl fluorideAryl halideCarbonitrileDialkyl etherEtherFluorobenzeneHalobenzeneHydrocarbon derivativeIsocoumaranNitrileOrganic nitrogen compoundOrganic oxygen compoundOrganofluorideOrganohalogen compoundOrganoheterocyclic compoundOrganonitrogen compoundOrganooxygen compoundOrganopnictogen compoundOxacyclePhenylbutylamineTertiary aliphatic amineTertiary amine2-benzofuranscyclic ethernitrileorganofluorine compoundtertiary amino compoundSolidlogp3.58logs-4.74solubility5.88e-03 g/llogp3.76pka_strongest_basic9.78iupac1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrileaverage_mass324.3919mono_mass324.163791509smilesCN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1formulaC20H21FN2OinchiInChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3inchikeyWSEQXVZVJXJVFP-UHFFFAOYSA-Npolar_surface_area36.26refractivity94.02polarizability35.3rotatable_bond_count5acceptor_count3donor_count0physiological_charge1formal_charge0Specdb::EiMs568Specdb::NmrOneD2022Specdb::NmrTwoD1957Specdb::CMs10912Specdb::CMs124990Specdb::CMs131650Specdb::CMs139384Specdb::MsMs441061Specdb::MsMs441062Specdb::MsMs441063Specdb::MsMs441064Specdb::MsMs441065Specdb::MsMs443252Specdb::MsMs443253Specdb::MsMs443254Specdb::MsMs443255Specdb::MsMs443256Specdb::MsMs443257Specdb::MsMs443258Specdb::MsMs443259Specdb::MsMs443260Specdb::MsMs443261Specdb::MsMs443262Specdb::MsMs443263Specdb::MsMs443264Specdb::MsMs443265Specdb::MsMs449019Specdb::MsMs449020Specdb::MsMs449021Specdb::MsMs449022Specdb::MsMs451119Specdb::MsMs2226411HMDB05038#<Reference:0x000055567403f2a8>#<Reference:0x000055567403f0f0>#<Reference:0x000055567403ef38>#<Reference:0x000055567403ed80>#<Reference:0x000055567403ebc8>#<Reference:0x000055567403ea10>#<Reference:0x000055567403e858>#<Reference:0x000055567403e5d8>#<Reference:0x000055567403e3f8>#<Reference:0x000055567403e240>#<Reference:0x000055567403e088>#<Reference:0x000055567403ded0>#<Reference:0x000055567403dd18>#<Reference:0x000055567403db60>#<Reference:0x000055567403d9a8>#<Reference:0x000055567403d7f0>#<Reference:0x000055567403d638>#<Reference:0x000055567403d480>#<Reference:0x000055567403d2a0>Cytochrome P450 2D6Q6NWU0CYP2D6Cytochrome P450, family 1, subfamily A, polypeptide 1A0N0X8CYP1A1