1.0 2011-09-21 00:39:29 UTC 2019-11-26 03:21:11 UTC FDB024075 11beta-Hydroxyandrost-4-ene-3,17-dione 11beta-Hydroxyandrost-4-ene-3,17-dione is an intermediate in adrenosterone production. 11beta-Hydroxyandrost-4-ene-3,17-dione is produced from androst-4-ene-3,17-dione, a reaction catalyzed by the enzyme cytochrome P450 B [EC:1.14.15.4]. 11beta-Hydroxyandrost-4-ene-3,17-dione is then converted into adrenosterone by the enzyme 11beta-hydroxysteroid dehydrogenase [EC:1.1.1.146]. [HMDB] 11b-Hydroxyandrost-4-ene-3,17-dione 11beta-Hydroxyandrost-4-ene-3,17-dione 11β-hydroxyandrost-4-ene-3,17-dione 4-Androsten-11b-ol-3,17-dione 4-Androsten-11beta-ol-3,17-dione 4-Androsten-11β-ol-3,17-dione Androst-4-ene-3,17-dione-11b-ol Androst-4-ene-3,17-dione-11beta-ol Androst-4-ene-3,17-dione-11β-ol C19H26O3 302.4079 302.188194698 (1S,2R,10S,11S,15S,17S)-17-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-ene-5,14-dione 4-androsten-11β-ol-3,17-dione 382-44-5 [H][C@@]12CCC(=O)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C InChI=1S/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-15,17,21H,3-8,10H2,1-2H3/t13-,14-,15-,17+,18-,19-/m0/s1 WSCUHXPGYUMQEX-KCZNZURUSA-N belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. Androgens and derivatives Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Androstane steroids Aliphatic homopolycyclic compounds 11-beta-hydroxysteroids 17-oxosteroids 3-oxo delta-4-steroids Cyclic alcohols and derivatives Cyclohexenones Delta-4-steroids Hydrocarbon derivatives Organic oxides Secondary alcohols 11-beta-hydroxysteroid 11-hydroxysteroid 17-oxosteroid 3-oxo-delta-4-steroid 3-oxosteroid Alcohol Aliphatic homopolycyclic compound Androgen-skeleton Carbonyl group Cyclic alcohol Cyclic ketone Cyclohexenone Delta-4-steroid Hydrocarbon derivative Hydroxysteroid Ketone Organic oxide Organic oxygen compound Organooxygen compound Oxosteroid Secondary alcohol 11beta-hydroxy steroid 17-oxo steroid 3-oxo steroid C19 steroids (androgens) and derivatives C19 steroids (androgens) and derivatives androstanoid Solid logp 2.00 ALOGPS logs -3.57 ALOGPS solubility 8.21e-02 g/l ALOGPS logp 2.62 ChemAxon pka_strongest_acidic 14.88 ChemAxon pka_strongest_basic -2.9 ChemAxon iupac (1S,2R,10S,11S,15S,17S)-17-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-ene-5,14-dione ChemAxon average_mass 302.4079 ChemAxon mono_mass 302.188194698 ChemAxon smiles [H][C@@]12CCC(=O)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C ChemAxon formula C19H26O3 ChemAxon inchi InChI=1S/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-15,17,21H,3-8,10H2,1-2H3/t13-,14-,15-,17+,18-,19-/m0/s1 ChemAxon inchikey WSCUHXPGYUMQEX-KCZNZURUSA-N ChemAxon polar_surface_area 54.37 ChemAxon refractivity 85.2 ChemAxon polarizability 34 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 2207 Specdb::CMs 2208 Specdb::CMs 19115 Specdb::CMs 31544 Specdb::CMs 31545 Specdb::CMs 31922 Specdb::CMs 31923 Specdb::CMs 31924 Specdb::CMs 31925 Specdb::CMs 39084 Specdb::CMs 145821 Specdb::MsMs 308476 Specdb::MsMs 308477 Specdb::MsMs 308478 Specdb::MsMs 352654 Specdb::MsMs 352655 Specdb::MsMs 352656 Specdb::MsMs 2236391 Specdb::MsMs 2237006 Specdb::MsMs 2238525 Specdb::MsMs 2239040 Specdb::MsMs 2240513 Specdb::MsMs 2241203 Specdb::MsMs 2242551 Specdb::MsMs 2243279 Specdb::MsMs 2244692 Specdb::MsMs 2313344 Specdb::MsMs 2313345 Specdb::MsMs 2313346 Specdb::MsMs 2652335 Specdb::MsMs 2652336 Specdb::MsMs 2652337 HMDB06773 Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Milk (Cow) Type 2 specific Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 Corticosteroid 11-beta-dehydrogenase isozyme 1 P28845 HSD11B1