Record Information
Version1.0
Creation date2011-09-21 01:28:50 UTC
Update date2016-06-28 20:13:27 UTC
Primary IDFDB027720
Secondary Accession NumbersNot Available
Chemical Information
FooDB NamePG(16:0/16:0)
DescriptionPG(16:0/16:0) is a phosphatidylglycerol. Phosphatidylglycerols consist of a glycerol 3-phosphate backbone esterified to either saturated or unsaturated fatty acids on carbons 1 and 2. As is the case with diacylglycerols, phosphatidylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions. PG(16:0/16:0), in particular, consists of two hexadecanoyl chains at positions C-1 and C-2. In E. coli glycerophospholipid metabolism, phosphatidylglycerol is formed from phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by a sequence of enzymatic reactions that proceeds via two intermediates, cytidine diphosphate diacylglycerol (CDP-diacylglycerol) and phosphatidylglycerophosphate (PGP, a phosphorylated phosphatidylglycerol). Phosphatidylglycerols, along with CDP-diacylglycerol, also serve as precursor molecules for the synthesis of cardiolipin, a phospholipid found in membranes.
CAS NumberNot Available
Structure
Thumb
Synonyms
SynonymSource
1,2-Dihexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)ChEBI
1,2-DihexadecanoylphosphatidylglycerolChEBI
1,2-DipalmitoylphosphatidylglycerolChEBI
DihexadecanoylphosphatidylglycerolChEBI
DipalmitoylphosphatidylglycerolChEBI
GPG(16:0/16:0)ChEBI
GPG(32:0)ChEBI
PG(32:0)ChEBI
Phosphatidylglycerol(16:0/16:0)ChEBI
Phosphatidylglycerol(32:0)ChEBI
1,2-Dihexadecanoyl-rac-glycero-3-phospho-(1'-rac-glycerol)HMDB
1,2-Dipalmitoyl-rac-glycero-3-phosphoglycerolHMDB
1,2-Dihexadecanoyl-rac-glycero-3-phospho-(1'-glycerol)HMDB
1,2-Dihexadecanoyl-rac-glycero-3-phosphoglycerolHMDB
PG(16:0/16:0)Lipid Annotator
Bacteriocin 28b protein, bacteriaMeSH
Bacteriocin 28b structural protein, bacteriaMeSH
BSS Protein, bacteriaMeSH
1,2-Dihexadecanoyl-rac-glycero-3-O-(1'-rac-glycerol)HMDB
1,2-dihexadecanoyl-rac-glycero-3-phospho-(1'-rac-glycerol)hmdb
1,2-Dihexadecanoyl-sn-glycero-3-O-(1'-sn-glycerol)ChEBI
1,2-DihexadecanoylatidylglycerolChEBI
1,2-Dipalmitoyl-rac-glycero-3-oglycerolHMDB
1,2-dipalmitoyl-rac-glycero-3-phosphoglycerolhmdb
1,2-DipalmitoylatidylglycerolChEBI
Atidylglycerol(16:0/16:0)ChEBI
Atidylglycerol(32:0)ChEBI
DihexadecanoylatidylglycerolChEBI
DipalmitoylatidylglycerolChEBI
Predicted Properties
PropertyValueSource
Water Solubility0.00014 g/LALOGPS
logP7.8ALOGPS
logP10.94ChemAxon
logS-6.7ALOGPS
pKa (Strongest Acidic)1.89ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area148.82 ŲChemAxon
Rotatable Bond Count40ChemAxon
Refractivity195.31 m³·mol⁻¹ChemAxon
Polarizability88.02 ųChemAxon
Number of Rings0ChemAxon
Bioavailability0ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Chemical FormulaC38H75O10P
IUPAC name[(2R)-2,3-bis(hexadecanoyloxy)propoxy][(2S)-2,3-dihydroxypropoxy]phosphinic acid
InChI IdentifierInChI=1S/C38H75O10P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-37(41)45-33-36(34-47-49(43,44)46-32-35(40)31-39)48-38(42)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h35-36,39-40H,3-34H2,1-2H3,(H,43,44)/t35-,36+/m0/s1
InChI KeyBIABMEZBCHDPBV-MPQUPPDSSA-N
Isomeric SMILES[H][C@](O)(CO)COP(O)(=O)OC[C@@]([H])(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC
Average Molecular Weight722.982
Monoisotopic Molecular Weight722.509785613
Classification
Description belongs to the class of organic compounds known as phosphatidylglycerols. These are glycerophosphoglycerols in which two fatty acids are bonded to the 1-glycerol moiety through ester linkages. As is the case with diacylglycerols, phosphatidylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassGlycerophospholipids
Sub ClassGlycerophosphoglycerols
Direct ParentPhosphatidylglycerols
Alternative Parents
Substituents
  • 1,2-diacylglycerophosphoglycerol
  • Fatty acid ester
  • Dialkyl phosphate
  • Dicarboxylic acid or derivatives
  • Organic phosphoric acid derivative
  • Phosphoric acid ester
  • Alkyl phosphate
  • Fatty acyl
  • 1,2-diol
  • Carboxylic acid ester
  • Secondary alcohol
  • Carboxylic acid derivative
  • Organic oxide
  • Organooxygen compound
  • Alcohol
  • Organic oxygen compound
  • Primary alcohol
  • Carbonyl group
  • Hydrocarbon derivative
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Ontology
Physiological effect

Organoleptic effect:

Disposition

Route of exposure:

Source:

Biological location:

Process

Naturally occurring process:

Role

Industrial application:

Biological role:

Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateSolid
Physical DescriptionNot Available
Mass CompositionNot Available
Melting PointNot Available
Boiling PointNot Available
Experimental Water SolubilityNot Available
Experimental logPNot Available
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
DensityNot Available
Refractive IndexNot Available
Spectra
Spectra
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-06g0-4280921800-3812aaeaa5264b7d3996View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-0ara-7392521200-d091073ee8d840756501View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0a6s-9252222000-d6d1efc378f0e4a795c6View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-0abi-0190401300-0bf9848a378dc29fbf10View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-0a6r-5291201000-7a60f9a13e177a4222a7View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-004i-9020000000-ce91b99bb7a15906af4cView in MoNA
ChemSpider ID393791
ChEMBL IDNot Available
KEGG Compound IDNot Available
Pubchem Compound ID446440
Pubchem Substance IDNot Available
ChEBI IDNot Available
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDHMDB10570
CRC / DFC (Dictionary of Food Compounds) IDNot Available
EAFUS IDNot Available
Dr. Duke IDNot Available
BIGG IDNot Available
KNApSAcK IDNot Available
HET IDLHG
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDNot Available
SuperScent IDNot Available
Wikipedia IDNot Available
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / BioactivitiesNot Available
Enzymes
NameGene NameUniProt ID
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1LPGAT1Q92604
Pathways
NameSMPDB LinkKEGG Link
Phospholipid BiosynthesisSMP00025 map00564
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
FlavoursNot Available
Files
MSDSNot Available
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference