1.0 2011-09-21 01:45:41 UTC 2015-07-21 06:59:33 UTC FDB028830 5-Aminopentanamide 5-Aminopentanamide is involved in the lysine degradation IV pathway. It can be generated from the enzymatic reduction of 5-aminopentanoate or enzymatic oxidation of L-lysine Pseudomonas putida can catabolize L-lysine via the δ-aminovalerate (AMV) (5-aminopentanoate) pathway to glutarate. In this pathway, L-lysine is transported into the cell by basic amino acid transport systems. It is oxidatively decarboxylated to 5-aminopentanamide, which is then hydrolyzed to 5-aminopentanoate and ammonia. The conversion of 5-aminopentanoate to glutarate involves gene products of the davDT operon. Activation of glutarate to glutaryl-CoA by an as yet uncharacterized reaction(s) and further metabolism of glutaryl-CoA to carbon dioxide and acetyl-CoA have been demonstrated in Pseudomonas fluorescens [HMDB] 5-aminovaleramide 5-Aminovalerate amide 5-aminovaleric acid amide C5H12N2O 116.1616 116.094963016 5-aminopentanamide aminopentamide 13023-70-6 NCCCCC(N)=O InChI=1S/C5H12N2O/c6-4-2-1-3-5(7)8/h1-4,6H2,(H2,7,8) OTIAVLWNTIXJDO-UHFFFAOYSA-N belongs to the class of organic compounds known as delta amino acids and derivatives. Delta amino acids and derivatives are compounds containing a carboxylic acid group and an amino group at the C5 carbon atom. Delta amino acids and derivatives Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Aliphatic acyclic compounds Carbonyl compounds Fatty amides Hydrocarbon derivatives Monoalkylamines Organic oxides Organopnictogen compounds Primary carboxylic acid amides Aliphatic acyclic compound Amine Carbonyl group Carboxamide group Delta amino acid or derivatives Fatty acyl Fatty amide Hydrocarbon derivative Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary aliphatic amine Primary amine Primary carboxylic acid amide fatty amide Solid logp -2.00 ALOGPS logs 0.08 ALOGPS solubility 1.39e+02 g/l ALOGPS logp -0.98 ChemAxon pka_strongest_acidic 16.94 ChemAxon pka_strongest_basic 9.91 ChemAxon iupac 5-aminopentanamide ChemAxon average_mass 116.1616 ChemAxon mono_mass 116.094963016 ChemAxon smiles NCCCCC(N)=O ChemAxon formula C5H12N2O ChemAxon inchi InChI=1S/C5H12N2O/c6-4-2-1-3-5(7)8/h1-4,6H2,(H2,7,8) ChemAxon inchikey OTIAVLWNTIXJDO-UHFFFAOYSA-N ChemAxon polar_surface_area 69.11 ChemAxon refractivity 31.88 ChemAxon polarizability 13.03 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 2 ChemAxon donor_count 2 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon Specdb::NmrOneD 95638 Specdb::NmrOneD 95639 Specdb::NmrOneD 95640 Specdb::NmrOneD 95641 Specdb::NmrOneD 95642 Specdb::NmrOneD 95643 Specdb::NmrOneD 95644 Specdb::NmrOneD 95645 Specdb::NmrOneD 95646 Specdb::NmrOneD 95647 Specdb::NmrOneD 95648 Specdb::NmrOneD 95649 Specdb::NmrOneD 95650 Specdb::NmrOneD 95651 Specdb::NmrOneD 95652 Specdb::NmrOneD 95653 Specdb::NmrOneD 95654 Specdb::NmrOneD 95655 Specdb::NmrOneD 95656 Specdb::NmrOneD 95657 Specdb::MsIr 2685 Specdb::MsIr 2686 Specdb::MsIr 2687 Specdb::CMs 18593 Specdb::CMs 156055 Specdb::MsMs 307261 Specdb::MsMs 307262 Specdb::MsMs 307263 Specdb::MsMs 351163 Specdb::MsMs 351164 Specdb::MsMs 351165 Specdb::MsMs 2377966 Specdb::MsMs 2377967 Specdb::MsMs 2377968 Specdb::MsMs 2557020 Specdb::MsMs 2557021 Specdb::MsMs 2557022 HMDB12176 18120 Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823