1.0 2011-09-26 22:54:03 UTC 2025-11-19 02:58:23 UTC FDB029672 1,2,4,5-tetramethylbenzene Durene also known as 1,2,4,5-tetramethylbenzene, belongs to the class of organic compounds known as benzene and substituted derivatives. These are aromatic compounds containing one monocyclic ring system consisting of benzene. The compound is classified as an alkylbenzene. It is one of three isomers of tetramethylbenzene, the other two being prehnitene (1,2,3,4-tetramethylbenzene) and isodurene (1,2,3,5-tetramethylbenzene). Durene has an unusually high melting point (79.2 °C), reflecting its high molecular symmetry. It is a component of coal tar and was first prepared from pseudocumene in 1870. It is produced by methylation of other methylated benzene compounds such as p-xylene and pseudocumene (DOI: 10.15227/orgsyn.010.0032). Durene is a colourless solid with a sweet odor. It is also a sweet and rancid tasting compound. Durene has been detected, but not quantified, in sweet cherries. C10H14 134.222 134.109550451 1,2,4,5-tetramethylbenzene durene 95-93-2 CC1=CC(C)=C(C)C=C1C InChI=1S/C10H14/c1-7-5-9(3)10(4)6-8(7)2/h5-6H,1-4H3 SQNZJJAZBFDUTD-UHFFFAOYSA-N belongs to the class of organic compounds known as benzene and substituted derivatives. These are aromatic compounds containing one monocyclic ring system consisting of benzene. Benzene and substituted derivatives Organic compounds Benzenoids Benzene and substituted derivatives Aromatic homomonocyclic compounds Aromatic hydrocarbons Unsaturated hydrocarbons Aromatic homomonocyclic compound Aromatic hydrocarbon Hydrocarbon Monocyclic benzene moiety Unsaturated hydrocarbon tetramethylbenzene logp 4.05 ALOGPS logs -3.65 ALOGPS solubility 3.03e-02 g/l ALOGPS logp 4.03 ChemAxon iupac 1,2,4,5-tetramethylbenzene ChemAxon average_mass 134.222 ChemAxon mono_mass 134.109550451 ChemAxon smiles CC1=CC(C)=C(C)C=C1C ChemAxon formula C10H14 ChemAxon inchi InChI=1S/C10H14/c1-7-5-9(3)10(4)6-8(7)2/h5-6H,1-4H3 ChemAxon inchikey SQNZJJAZBFDUTD-UHFFFAOYSA-N ChemAxon polar_surface_area 0 ChemAxon refractivity 46.22 ChemAxon polarizability 17.15 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 0 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 102876 Specdb::CMs 126866 Specdb::MsMs 91281 Specdb::MsMs 91282 Specdb::MsMs 91283 Specdb::MsMs 154632 Specdb::MsMs 154633 Specdb::MsMs 154634 Specdb::MsMs 3394099 Specdb::MsMs 3394100 Specdb::MsMs 3394101 Specdb::MsMs 3394102 Specdb::MsMs 3394103 Specdb::MsMs 3394104 Sweet cherry Type 1 specific Prunus avium 42229 rancid sweet