Record Information
Version1.0
Creation date2015-05-07 21:27:20 UTC
Update date2019-11-27 17:46:04 UTC
Primary IDFDB031256
Secondary Accession NumbersNot Available
Chemical Information
FooDB NameZn2+
DescriptionZinc, also known as zinc ion or zn2+, is a member of the class of compounds known as homogeneous transition metal compounds. Homogeneous transition metal compounds are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom. Zinc can be found in a number of food items such as sunburst squash (pattypan squash), star fruit, kelp, and common salsify, which makes zinc a potential biomarker for the consumption of these food products. Zinc can be found primarily in blood, cerebrospinal fluid (CSF), saliva, and urine, as well as in human brain, erythrocyte and liver tissues. Zinc exists in all living species, ranging from bacteria to humans. In humans, zinc is involved in several metabolic pathways, some of which include pantoprazole action pathway, pyruvate metabolism, cimetidine action pathway, and phenylbutazone action pathway. Zinc is also involved in several metabolic disorders, some of which include gamma-glutamyltransferase deficiency, 3-phosphoglycerate dehydrogenase deficiency, MNGIE (mitochondrial neurogastrointestinal encephalopathy), and cystathionine beta-synthase deficiency. Moreover, zinc is found to be associated with continuous ambulatory peritoneal dialysis, kidney disease, chronic renal failure, and hemodialysis. Zinc is a non-carcinogenic (not listed by IARC) potentially toxic compound. The element was probably named by the alchemist Paracelsus after the German word Zinke (prong, tooth). German chemist Andreas Sigismund Marggraf is credited with discovering pure metallic zinc in 1746. Work by Luigi Galvani and Alessandro Volta uncovered the electrochemical properties of zinc by 1800. Corrosion-resistant zinc plating of iron (hot-dip galvanizing) is the major application for zinc. Other applications are in electrical batteries, small non-structural castings, and alloys such as brass. A variety of zinc compounds are commonly used, such as zinc carbonate and zinc gluconate (as dietary supplements), zinc chloride (in deodorants), zinc pyrithione (anti-dandruff shampoos), zinc sulfide (in luminescent paints), and zinc methyl or zinc diethyl in the organic laboratory . Ingestion of large doses of zinc causes stomach cramps, nausea, and vomiting. Acute inhalation of large amounts of zinc causes metal fume fever, which is characterized by chills, fever, headache, weakness, dryness of the nose and throat, chest pain, and coughing. Dermal contact with zinc results in skin irritation (L49) (T3DB).
CAS Number23713-49-7
Structure
Thumb
Synonyms
SynonymSource
Dietary zincChEBI
Zinc cationChEBI
ZINC ionChEBI
Zinc, ion (ZN2+)ChEBI
ZN(II)ChEBI
ZN(2+)ChEBI
ZN2+ChEBI
Mannosidase b, alphaMeSH
alpha Mannosidase bMeSH
alpha-D-Mannoside mannohydrolaseMeSH
Neutral alpha-mannosidaseMeSH
alpha D MannosidaseMeSH
alpha-D-MannosidaseMeSH
Lysosomal alpha-mannosidaseMeSH
Mannohydrolase, alpha-D-mannosideMeSH
alpha MannosidaseMeSH
alpha-MannosidaseMeSH
LAMANMeSH
Lysosomal alpha mannosidaseMeSH
Neutral alpha mannosidaseMeSH
alpha D Mannoside mannohydrolaseMeSH
alpha-Mannosidase, lysosomalMeSH
alpha-Mannosidase, neutralMeSH
Topostin bMeSH
Predicted Properties
PropertyValueSource
logP0.16ChemAxon
Physiological Charge2ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m³·mol⁻¹ChemAxon
Polarizability1.78 ųChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Chemical FormulaZn
IUPAC namezinc(2+) ion
InChI IdentifierInChI=1S/Zn/q+2
InChI KeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
Isomeric SMILES[Zn++]
Average Molecular Weight65.409
Monoisotopic Molecular Weight63.929146578
Classification
Description belongs to the class of inorganic compounds known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom.
KingdomInorganic compounds
Super ClassHomogeneous metal compounds
ClassHomogeneous transition metal compounds
Sub ClassNot Available
Direct ParentHomogeneous transition metal compounds
Alternative ParentsNot Available
Substituents
  • Homogeneous transition metal
Molecular FrameworkNot Available
External Descriptors
Ontology
Physiological effect

Health effect:

Disposition

Route of exposure:

Source:

Biological location:

Role

Industrial application:

Biological role:

Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateNot Available
Physical DescriptionNot Available
Mass CompositionNot Available
Melting PointNot Available
Boiling PointNot Available
Experimental Water SolubilityNot Available
Experimental logPNot Available
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
DensityNot Available
Refractive IndexNot Available
Spectra
Spectra
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-03di-9000000000-0cd08967c771fb645329View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-03di-9000000000-0cd08967c771fb645329View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-03di-9000000000-0cd08967c771fb645329View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-03di-9000000000-29976d3ebd17b2d11a4bView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-03di-9000000000-29976d3ebd17b2d11a4bView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-03di-9000000000-29976d3ebd17b2d11a4bView in MoNA
ChemSpider IDNot Available
ChEMBL IDNot Available
KEGG Compound IDNot Available
Pubchem Compound IDNot Available
Pubchem Substance IDNot Available
ChEBI IDNot Available
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDNot Available
CRC / DFC (Dictionary of Food Compounds) IDNot Available
EAFUS IDNot Available
Dr. Duke IDNot Available
BIGG IDNot Available
KNApSAcK IDNot Available
HET IDNot Available
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDNot Available
SuperScent IDNot Available
Wikipedia IDNot Available
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / BioactivitiesNot Available
EnzymesNot Available
PathwaysNot Available
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
FlavoursNot Available
Files
MSDSNot Available
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference