Record Information
Version1.0
Creation date2019-08-08 20:44:29 UTC
Update date2019-08-08 20:44:29 UTC
Primary IDFDB052955
Secondary Accession NumbersNot Available
Chemical Information
FooDB NameCL(i-12:0/18:2(9Z,11Z)/a-25:0/i-13:0)[rac]
DescriptionCL(i-12:0/18:2(9Z,11Z)/a-25:0/i-13:0)[rac], also known as Cardiolipin(I-12:0/18:2/A-25:0/I-13:0) or CL(68:2), belongs to the class of organic compounds known as cardiolipins. These are glycerophospholipids in which the O1 and O3 oxygen atoms of the central glycerol moiety are each linked to one 1,2-diacylglycerol chain. Their general formula is OC(COP(O)(=O)OC[C@@H](CO[R1])O[R2])COP(O)(=O)OC[C@@H](CO[R3])O[R4], where R1-R4 are four fatty acyl chains. CL(i-12:0/18:2(9Z,11Z)/a-25:0/i-13:0)[rac] is an extremely weak basic (essentially neutral) compound (based on its pKa).
CAS NumberNot Available
Structure
Thumb
Synonyms
SynonymSource
CL(I-12:0/18:2/A-25:0/I-13:0)HMDB
CL(I-12:0/18:2N7/A-25:0/I-13:0)HMDB
CL(I-12:0/18:2W7/A-25:0/I-13:0)HMDB
CL(68:2)HMDB
Cardiolipin(I-12:0/18:2(9Z,11Z)/A-25:0/I-13:0)HMDB
Cardiolipin(I-12:0/18:2/A-25:0/I-13:0)HMDB
Cardiolipin(I-12:0/18:2N7/A-25:0/I-13:0)HMDB
Cardiolipin(I-12:0/18:2W7/A-25:0/I-13:0)HMDB
Cardiolipin(68:2)HMDB
CL(I-12:0/18:2(9Z,11Z)/A-25:0/I-13:0)HMDB
Predicted Properties
PropertyValueSource
Water Solubility5.3e-05 g/LALOGPS
logP8.69ALOGPS
logP24.29ChemAxon
logS-7.4ALOGPS
pKa (Strongest Acidic)1.59ChemAxon
pKa (Strongest Basic)-3.4ChemAxon
Physiological Charge-2ChemAxon
Hydrogen Acceptor Count9ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area236.95 ŲChemAxon
Rotatable Bond Count77ChemAxon
Refractivity390.58 m³·mol⁻¹ChemAxon
Polarizability170.34 ųChemAxon
Number of Rings0ChemAxon
Bioavailability0ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Chemical FormulaC77H146O17P2
IUPAC name[(2R)-2-hydroxy-3-({hydroxy[(2R)-2-[(11-methyldodecanoyl)oxy]-3-[(22-methyltetracosanoyl)oxy]propoxy]phosphoryl}oxy)propoxy][(2R)-3-[(10-methylundecanoyl)oxy]-2-[(9Z,11Z)-octadeca-9,11-dienoyloxy]propoxy]phosphinic acid
InChI IdentifierInChI=1S/C77H146O17P2/c1-8-10-11-12-13-14-15-16-21-26-29-32-37-46-53-60-76(81)93-73(65-88-75(80)59-52-45-40-39-42-49-56-69(5)6)67-92-96(85,86)90-63-71(78)62-89-95(83,84)91-66-72(94-77(82)61-54-47-38-33-34-41-48-55-68(3)4)64-87-74(79)58-51-44-36-31-28-25-23-20-18-17-19-22-24-27-30-35-43-50-57-70(7)9-2/h14-16,21,68-73,78H,8-13,17-20,22-67H2,1-7H3,(H,83,84)(H,85,86)/b15-14-,21-16-/t70?,71-,72-,73-/m1/s1
InChI KeyRNZGNMQWFNYWCU-IDDBUOAISA-N
Isomeric SMILES[H][C@@](O)(COP(O)(=O)OC[C@@]([H])(COC(=O)CCCCCCCCCCCCCCCCCCCCC(C)CC)OC(=O)CCCCCCCCCC(C)C)COP(O)(=O)OC[C@@]([H])(COC(=O)CCCCCCCCC(C)C)OC(=O)CCCCCCC\C=C/C=C\CCCCCC
Average Molecular Weight1405.946
Monoisotopic Molecular Weight1405.003527237
Classification
Description belongs to the class of organic compounds known as cardiolipins. These are glycerophospholipids in which the O1 and O3 oxygen atoms of the central glycerol moiety are each linked to one 1,2-diacylglycerol chain. Their general formula is OC(COP(O)(=O)OC[C@@H](CO[R1])O[R2])COP(O)(=O)OC[C@@H](CO[R3])O[R4], where R1-R4 are four fatty acyl chains.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassGlycerophospholipids
Sub ClassGlycerophosphoglycerophosphoglycerols
Direct ParentCardiolipins
Alternative Parents
Substituents
  • Cardiolipin
  • Tetracarboxylic acid or derivatives
  • Fatty acid ester
  • Dialkyl phosphate
  • Organic phosphoric acid derivative
  • Phosphoric acid ester
  • Alkyl phosphate
  • Fatty acyl
  • Carboxylic acid ester
  • Secondary alcohol
  • Carboxylic acid derivative
  • Organooxygen compound
  • Alcohol
  • Organic oxide
  • Organic oxygen compound
  • Hydrocarbon derivative
  • Carbonyl group
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External DescriptorsNot Available
Ontology
Physiological effect

Organoleptic effect:

Disposition

Route of exposure:

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Source:

Process

Naturally occurring process:

Role

Biological role:

Industrial application:

Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateNot Available
Physical DescriptionNot Available
Mass CompositionNot Available
Melting PointNot Available
Boiling PointNot Available
Experimental Water SolubilityNot Available
Experimental logPNot Available
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
DensityNot Available
Refractive IndexNot Available
Spectra
Spectra
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-0udi-0131000900-a7adab0fd7f23ba333f4View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-0udi-0134111900-414d4e1401cde8355132View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-02c2-0379320000-061e69e83b280d73c639View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-00kr-1967112201-00cbc0d98cbf0470bf1bView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-00kr-1956022200-a60987a0b28cc507fca1View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0ap0-3967357301-dabb3dd6d91209816e67View in MoNA
ChemSpider IDNot Available
ChEMBL IDNot Available
KEGG Compound IDNot Available
Pubchem Compound IDNot Available
Pubchem Substance IDNot Available
ChEBI IDNot Available
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDNot Available
CRC / DFC (Dictionary of Food Compounds) IDNot Available
EAFUS IDNot Available
Dr. Duke IDNot Available
BIGG IDNot Available
KNApSAcK IDNot Available
HET IDNot Available
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDNot Available
SuperScent IDNot Available
Wikipedia IDNot Available
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / BioactivitiesNot Available
EnzymesNot Available
PathwaysNot Available
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
FlavoursNot Available
Files
MSDSNot Available
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference