| Record Information |
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| Version | 1.0 |
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| Creation date | 2010-04-08 22:04:40 UTC |
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| Update date | 2025-11-18 22:21:12 UTC |
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| Primary ID | FDB000693 |
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| Secondary Accession Numbers | Not Available |
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| Chemical Information |
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| FooDB Name | Diosmetin 7-rutinoside |
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| Description | Diosmin belongs to the class of organic compounds known as flavonoid-7-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position. Diosmin is found, on average, in the highest concentration within a few different foods, such as hyssops (Hyssopus officinalis), peppermints (Mentha X piperita), and lemons (Citrus limon). Diosmin has also been detected, but not quantified in, several different foods, such as green vegetables, mandarin orange (clementine, tangerine), rosemaries (Rosmarinus officinalis), spearmints (Mentha spicata), and sweet oranges (Citrus sinensis). This could make diosmin a potential biomarker for the consumption of these foods. Based on a literature review very few articles have been published on Diosmin. |
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| CAS Number | 520-27-4 |
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| Structure | |
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| Synonyms | | Synonym | Source |
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| 5,7,3'-Trihydroxy-4'-methoxyflavone 7-O-rutinoside | HMDB | | Barosmin | HMDB | | Daflon | HMDB | | Diosmetin 7-O-rutinoside | HMDB | | Diosmetin 7-rutinoside | HMDB | | Diosmetin-7-O-rutinoside | HMDB | | Diosmil | HMDB | | Diosmin, ban, inn | HMDB | | Diosmine | HMDB | | Diosminum | HMDB | | Diovenor | HMDB | | Flebosten | HMDB | | Luteolin 4'-methyl ether 7-rutinoside | HMDB | | Rioven | HMDB | | Salinigricoflavonoloside | HMDB | | Tovene | HMDB | | Ven-detrex | HMDB | | veno-V | HMDB | | Venosmine | HMDB | | Diosmin, BAN, INN | db_source | | Ven-Detrex | db_source | | Veno-v | HMDB |
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| Predicted Properties | |
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| Chemical Formula | C28H32O15 |
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| IUPAC name | 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(3,4,5-trihydroxy-6-{[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]methyl}oxan-2-yl)oxy]-4H-chromen-4-one |
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| InChI Identifier | InChI=1S/C28H32O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-8,10,19,21-30,32-37H,9H2,1-2H3 |
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| InChI Key | GZSOSUNBTXMUFQ-UHFFFAOYSA-N |
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| Isomeric SMILES | COC1=C(O)C=C(C=C1)C1=CC(=O)C2=C(O1)C=C(OC1OC(COC3OC(C)C(O)C(O)C3O)C(O)C(O)C1O)C=C2O |
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| Average Molecular Weight | 608.5447 |
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| Monoisotopic Molecular Weight | 608.174120354 |
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| Classification |
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| Description | Belongs to the class of organic compounds known as flavonoid-7-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position. |
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| Kingdom | Organic compounds |
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| Super Class | Phenylpropanoids and polyketides |
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| Class | Flavonoids |
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| Sub Class | Flavonoid glycosides |
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| Direct Parent | Flavonoid-7-O-glycosides |
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| Alternative Parents | |
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| Substituents | - Flavonoid-7-o-glycoside
- 4p-methoxyflavonoid-skeleton
- 3'-hydroxyflavonoid
- 5-hydroxyflavonoid
- Flavone
- Hydroxyflavonoid
- Phenolic glycoside
- Chromone
- Disaccharide
- Glycosyl compound
- O-glycosyl compound
- Benzopyran
- Methoxyphenol
- 1-benzopyran
- Phenoxy compound
- Anisole
- Methoxybenzene
- Phenol ether
- Phenol
- Pyranone
- 1-hydroxy-2-unsubstituted benzenoid
- Alkyl aryl ether
- 1-hydroxy-4-unsubstituted benzenoid
- Benzenoid
- Oxane
- Pyran
- Monocyclic benzene moiety
- Vinylogous acid
- Heteroaromatic compound
- Secondary alcohol
- Polyol
- Acetal
- Organoheterocyclic compound
- Oxacycle
- Ether
- Organooxygen compound
- Alcohol
- Hydrocarbon derivative
- Organic oxygen compound
- Organic oxide
- Aromatic heteropolycyclic compound
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| Molecular Framework | Aromatic heteropolycyclic compounds |
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| External Descriptors | Not Available |
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| Ontology |
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| Disposition | Route of exposure: Source: Biological location: |
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| Role | Industrial application: |
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| Physico-Chemical Properties |
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| Physico-Chemical Properties - Experimental | | Property | Value | Reference |
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| Physical state | Not Available | |
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| Physical Description | Not Available | |
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| Mass Composition | C 55.26%; H 5.30%; O 39.44% | DFC |
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| Melting Point | Mp 280 dec. (in vacuo) | DFC |
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| Boiling Point | Not Available | |
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| Experimental Water Solubility | Not Available | |
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| Experimental logP | 0.14 | PERRISSOUD,D & TESTA,B (1986) |
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| Experimental pKa | Not Available | |
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| Isoelectric point | Not Available | |
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| Charge | Not Available | |
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| Optical Rotation | Not Available | |
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| Spectroscopic UV Data | 345 () (MeOH) (Berdy) | DFC |
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| Density | Not Available | |
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| Refractive Index | Not Available | |
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| Spectra |
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| Spectra | |
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| EI-MS/GC-MS | | Type | Description | Splash Key | View |
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| Predicted GC-MS | Diosmetin 7-rutinoside, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | splash10-0007-7432290000-d70f47a129b3142c35cb | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, 1 TMS, Predicted GC-MS Spectrum - 70eV, Positive | splash10-0900-6331019000-bde6242eed34a2bd808d | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_1_2, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_1_3, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_1_4, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_1_5, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_1_6, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_1_7, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_1_8, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_1, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_2, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_3, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_4, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_5, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_6, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_7, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_8, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_9, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_10, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_11, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_12, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_13, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_14, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_15, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Diosmetin 7-rutinoside, TMS_2_16, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum |
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| MS/MS | | Type | Description | Splash Key | View |
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| MS/MS | LC-MS/MS Spectrum - LC-ESI-qTof , Positive | splash10-0udi-0249000000-bd1d2df9c9ae8a17841f | 2017-09-14 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - Linear Ion Trap , negative | splash10-0002-0090000000-d4179a0eac71cee296c4 | 2017-09-14 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - Linear Ion Trap , negative | splash10-0002-0090000000-2d58a9e098baf7884b31 | 2017-09-14 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - Linear Ion Trap , positive | splash10-03di-0001900000-cb8633696196ba8d631a | 2017-09-14 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - Linear Ion Trap , positive | splash10-03di-0001900000-0804b33b8df38a53f208 | 2017-09-14 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - Linear Ion Trap , positive | splash10-0089-0009100000-02518ed6c111bd22a8f2 | 2017-09-14 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - Linear Ion Trap , positive | splash10-0089-0009100000-33682b6050606a7b1811 | 2017-09-14 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - , positive | splash10-0udi-0249000000-bd1d2df9c9ae8a17841f | 2017-09-14 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-001i-0090000000-6c0964f69118a53d9c02 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-0udi-0009403000-576343b0109027111529 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-0bt9-0008903000-60aff456412fa112c030 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-0002-0091000000-7022821f0c4a5d745678 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 10V, Positive | splash10-08fr-0004907000-5cb30d60fe09978a64b9 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-0002-0091000000-12577c1dd4b5cfa80125 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-0a4i-0020009000-dfe53d41d78137fd25f7 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 20V, Positive | splash10-0w29-0009400000-3bd7d8bfd41e0700368e | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 20V, Negative | splash10-0002-0090001000-af1d868643550c0db6ab | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-0a4i-0020009000-93ef6149b97e092e4a5a | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-0a4i-0020009000-ba94be76e265df4c7a26 | 2021-09-20 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0udl-0139153000-a5df8b8ace59185711f6 | 2015-04-24 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0udi-0149100000-745e0883625146afe113 | 2015-04-24 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0uei-1598000000-7d042cfcc8d7a6d00ffc | 2015-04-24 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0bta-3491236000-47db98d4ee7c0cbbd9d8 | 2015-04-25 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-0002-2490010000-590296c798c9902cd85c | 2015-04-25 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-000t-1190000000-3e769837d46cbf206b3d | 2015-04-25 | View Spectrum |
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| NMR | Not Available |
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| External Links |
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| ChemSpider ID | 4510141 |
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| ChEMBL ID | CHEMBL1707291 |
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| KEGG Compound ID | C10039 |
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| Pubchem Compound ID | 5353588 |
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| Pubchem Substance ID | Not Available |
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| ChEBI ID | Not Available |
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| Phenol-Explorer ID | 232 |
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| DrugBank ID | Not Available |
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| HMDB ID | HMDB29548 |
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| CRC / DFC (Dictionary of Food Compounds) ID | BKL03-G:BFP73-M |
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| EAFUS ID | Not Available |
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| Dr. Duke ID | DIOSMIN |
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| BIGG ID | Not Available |
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| KNApSAcK ID | C00004362 |
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| HET ID | Not Available |
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| Food Biomarker Ontology | Not Available |
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| VMH ID | Not Available |
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| Flavornet ID | Not Available |
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| GoodScent ID | Not Available |
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| SuperScent ID | Not Available |
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| Wikipedia ID | Not Available |
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| Phenol-Explorer Metabolite ID | Not Available |
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| Duplicate IDS | Not Available |
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| Old DFC IDS | Not Available |
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| Associated Foods |
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| Food | Content Range | Average | Reference |
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| Food | | | Reference |
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| Biological Effects and Interactions |
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| Health Effects / Bioactivities | | Descriptor | ID | Definition | Reference |
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| Anti-cancer | 35610 | An agent that inhibits the growth and proliferation of cancer cells, used to treat and manage various types of cancer, including chemotherapy, targeted therapy, and immunotherapy, to reduce tumor size, prevent metastasis, and improve patient survival. | DUKE | | Anti capillary-fragility | | An agent that strengthens capillary walls to prevent rupture, reducing bruising and bleeding. It plays a biological role in maintaining vascular integrity, and has therapeutic applications in treating conditions like purpura and hemorrhoids, with key medical uses in preventing and managing microvascular damage. | DUKE | | Anti carcinogenic | 35610 | An agent that prevents or inhibits the formation of cancer, reducing tumor growth and proliferation. It plays a biological role in protecting cells from DNA damage and mutation. Therapeutically, it is used to prevent cancer development, with key medical applications in chemotherapy, radiation protection, and cancer prevention programs. | DUKE | | Anti-clastogen | | An agent that inhibits mutagenic agents, preventing chromosome breakage and disruption, used to reduce genetic damage and cancer risk, with therapeutic applications in cancer prevention and treatment, and key medical uses in protecting against radiation and chemical-induced DNA damage. | DUKE | | Anti CVI | | An antibiotic that counteracts colicin V, a protein involved in E. coli immunity, used to combat bacterial infections and potentially applied in treating E. coli-related diseases. | DUKE | | Anti cytotoxic | 50247 | An agent that protects cells from toxic damage, reducing cell death and promoting survival. Its biological role involves mitigating oxidative stress and inflammation. Therapeutically, it has applications in cancer treatment, neuroprotection, and organ preservation, with key medical uses including chemotherapy adjuncts and neurodegenerative disease management. | DUKE | | Anti-edemic | | An agent that relieves or prevents edema, reducing abnormal fluid accumulation in tissues or the circulatory system, commonly used to treat conditions such as swelling, inflammation, and water retention. | DUKE | | Anti-hemorrhoidal | 52217 | An agent that reduces swelling and inflammation of hemorrhoids, commonly used to relieve symptoms of hemorrhoidal disease, such as itching, pain, and bleeding, and to prevent further complications. | DUKE | | Anti histaminic | 37956 | An agent that blocks histamine receptors, reducing allergic symptoms. Therapeutically, it alleviates itching, sneezing, and runny nose, commonly used in managing allergies, itching, and hives, as well as treating conditions like anaphylaxis and allergic rhinitis. | DUKE | | Anti-inflammatory | 35472 | An agent that reduces inflammation, playing a biological role in suppressing immune responses and therapeutic applications in managing pain, swelling, and redness. Key medical uses include treating arthritis, allergies, and autoimmune disorders, as well as relieving symptoms of conditions such as asthma and dermatitis. | DUKE | | Anti leukotriene | 35222 | An agent that blocks the action of leukotrienes, reducing inflammation and bronchoconstriction. Therapeutically, it is used to treat asthma, allergic rhinitis, and other respiratory disorders by inhibiting the biological role of leukotrienes in mediating inflammatory responses. | DUKE | | Anti-melanomic | 35610 | An agent that inhibits melanin production, reducing melanoma cell growth. It has therapeutic applications in treating skin cancers, particularly melanoma, and key medical uses include preventing tumor progression and metastasis, as well as managing pigmentation disorders. | DUKE | | Anti metastatic | 35610 | An agent that inhibits cancer cell spread, reducing tumor metastasis. It plays a biological role in blocking cell migration and invasion, and has therapeutic applications in cancer treatment. Key medical uses include preventing cancer recurrence and improving survival rates in patients with various types of cancer. | DUKE | | Anti metrorrhagic | | An agent that relieves abnormal uterine bleeding, playing a biological role in regulating menstrual flow. Therapeutically, it helps manage menorrhagia and metrorrhagia, with key medical uses including treatment of heavy menstrual bleeding, uterine fibroids, and other gynecological disorders. | DUKE | | Anti-oxidant | 22586 | An agent that neutralizes free radicals, reducing oxidative stress and cell damage. Its biological role involves protecting cells from harm, and it has therapeutic applications in managing chronic diseases, such as cancer, diabetes, and neurodegenerative disorders, with key medical uses including anti-aging, anti-inflammatory, and cardio protective effects. | DUKE | | Anti peroxidant | | An agent that prevents oxygen atom and peroxide formation, reducing oxidative stress and cell damage. It plays a biological role in protecting cells from free radicals. Therapeutically, it's used to manage conditions like cancer, Alzheimer's, and atherosclerosis, with key medical applications in neuroprotection, cardiovascular health, and anti-aging. | DUKE | | Anti proliferant | | An agent that prevents or inhibits cell growth and division, used therapeutically to treat cancer, manage tumor growth, and prevent restenosis after angioplasty, reducing abnormal cell proliferation. | DUKE | | Anti prostaglandin | 49020 | An agent that inhibits prostaglandin production, reducing inflammation and pain. Therapeutically, it's used to treat conditions like arthritis, menstrual cramps, and post-surgical pain, by blocking prostaglandin-mediated responses, providing relief from inflammation and discomfort. | DUKE | | Anti radicular | | An agent that relieves inflammation or irritation of the nerve root of a tooth, reducing pain and discomfort. Its biological role is to target and alleviate radicular pain, with therapeutic applications in endodontics and key medical uses in root canal treatments and tooth sensitivity management. | DUKE | | Anti thromboxane | 35222 | An agent that inhibits thromboxane A2, reducing platelet aggregation and blood clot formation. Therapeutically, it prevents thrombosis and is used to manage conditions like coronary artery disease, stroke, and myocardial infarction, as well as to prevent blood clots during surgeries. | DUKE | | Anti ulcer | 49201 | An agent that reduces stomach acid and protects the mucous lining, preventing ulcer formation. It is used to treat conditions like gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome, promoting healing and relieving symptoms. | DUKE | | Catechol O-methyltransferase inhibitor | 48406 | An agent that blocks the activity of catechol O-methyltransferase, an enzyme involved in breaking down catecholamines. Therapeutically, it increases dopamine levels, commonly used in managing Parkinson's disease, depression, and anxiety disorders, as well as treating pain and fibromyalgia. | DUKE | | Chemopreventive | 35610 | An agent that prevents or delays the development of cancer, reducing the risk of tumor formation and progression. It plays a biological role in inhibiting carcinogenesis, and has therapeutic applications in cancer prevention, with key medical uses including reducing the risk of colorectal, breast, and prostate cancers. | DUKE | | Cyclooxygenase inhibitor | 35544 | An agent that blocks the activity of cyclooxygenase enzymes, reducing inflammation and pain. Therapeutically, it is used to treat conditions such as arthritis, headaches, and menstrual cramps, by decreasing prostaglandin production, a key mediator of inflammation. | DUKE | | Cytochrome-P450 inhibitor | 50183 | An agent that blocks the activity of cytochrome-P450 enzymes, reducing drug metabolism. Therapeutically, it's used to increase the efficacy of certain medications, manage drug interactions, and treat conditions like erectile dysfunction, by inhibiting the breakdown of key drugs, allowing them to remain active in the body for a longer period. | DUKE | | Cytoprotective | | An agent that protects cells from damage caused by noxious chemicals, oxidative stress, or other harmful stimuli, playing a key role in preventing cell injury and death. Therapeutically, cytoprotectives are used to treat conditions such as gastroesophageal reflux disease, mucositis, and neurodegenerative disorders, with applications in oncology, gastroenterology, and neurology. | DUKE | | Diuretic | 35498 | An agent that increases urine production, helping remove excess fluids and salts from the body. It plays a key biological role in regulating fluid balance and blood pressure. Therapeutically, diuretics are used to treat conditions such as hypertension, edema, and heart failure, helping reduce swelling and lower blood pressure. | DUKE | | Hypoglycemic | 35526 | An agent that lowers blood glucose levels, playing a crucial role in glucose metabolism. Therapeutically, it is used to manage diabetes and insulin resistance, with key medical applications in treating type 1 and 2 diabetes, and preventing diabetic complications. | DUKE | | Lipoxygenase inhibitor | 35856 | An agent that blocks the activity of lipoxygenase enzymes, reducing inflammation and oxidative stress. Therapeutically, it's used to manage conditions like asthma, atherosclerosis, and cancer, by inhibiting the production of pro-inflammatory leukotrienes. Key medical uses include treating respiratory and cardiovascular diseases. | DUKE | | Multidrug resistance inhibitor | 35222 | An agent that blocks the efflux pumps in cancer cells, restoring sensitivity to chemotherapy drugs and overcoming drug resistance, commonly used in cancer treatment to enhance efficacy of anticancer medications. | DUKE | | Radioprotective | 35232 | An agent that shields cells from radiation damage, reducing oxidative stress and DNA harm. Its biological role is to mitigate radiation-induced injury, and it has therapeutic applications in cancer treatment, space exploration, and nuclear medicine, with key medical uses including protection of healthy tissues during radiation therapy. | DUKE | | Venoprotective | | An agent that protects the veins, alleviating or preventing conditions such as varicose veins, phlebitis, and venous insufficiency. It plays a biological role in strengthening vein walls and improving blood flow. Therapeutically, venoprotectives are used to reduce inflammation and swelling, commonly used in managing chronic venous disorders and preventing venous ulcers. | DUKE | | Venotonic | | An agent that promotes venous drainage, enhancing blood flow and reducing venous pressure. It plays a biological role in improving circulation and is therapeutically applied to treat conditions like varicose veins, edema, and chronic venous insufficiency, reducing symptoms of swelling and pain. | DUKE |
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| Enzymes | Not Available |
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| Pathways | Not Available |
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| Metabolism | Not Available |
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| Biosynthesis | Not Available |
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| Organoleptic Properties |
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| Flavours | Not Available |
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| Files |
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| MSDS | Not Available |
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| References |
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| Synthesis Reference | Not Available |
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| General Reference | Not Available |
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| Content Reference | — Rothwell JA, Pérez-Jiménez J, Neveu V, Medina-Ramon A, M'Hiri N, Garcia Lobato P, Manach C, Knox K, Eisner R, Wishart D, Scalbert A. (2013) Phenol-Explorer 3.0: a major update of the Phenol-Explorer database to incorporate data on the effects of food processing on polyphenol content. Database, 10.1093/database/bat070. — Duke, James. 'Dr. Duke's Phytochemical and Ethnobotanical Databases. United States Department of Agriculture.' Agricultural Research Service, Accessed April 27 (2004). — Shinbo, Y., et al. 'KNApSAcK: a comprehensive species-metabolite relationship database.' Plant Metabolomics. Springer Berlin Heidelberg, 2006. 165-181.
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