1.0 2010-04-08 22:04:41 UTC 2019-11-26 02:55:16 UTC FDB000709 (R)-Synephrine A widely distributed alkaloid, occurs in citrus leaves and juice and other plants R-Synephrine is the form found in nature. (+)-[(Methylamino)methyl]-benzenemethano (+)-P-Synephrine (+)-Synephrine (+/-)-synephrine 1-(4-Hydroxyphenyl)-2-(methylamino)ethanol 1-(4-Hydroxyphenyl)-2-methylaminoethanol 4-Hydroxy-a-[(methylamino)methyl]benzenemethanol 4-Hydroxy-alpha-[(methylamino)methyl]benzenemethanol 4-Hydroxy-α-[(methylamino)methyl]benzenemethanol b-Methylamino-a-(4-hydroxyphenyl)ethyl alcohol beta-Methylamino-alpha-(4-hydroxyphenyl)ethyl alcohol L-Synephrine Oxedrine P-Hydroxy-a-[(methylamino)methyl]benzyl alcohol P-Hydroxy-alpha-[(methylamino)methyl]benzyl alcohol P-Hydroxy-α-[(methylamino)methyl]benzyl alcohol p-Synephrine Parasympatol R-(-)-Synephrine Simpatol Sympaethamin Sympaethamine Sympatol Synephrine β-methylamino-α-(4-hydroxyphenyl)ethyl alcohol C9H13NO3 183.2044 183.089543287 4-[(R)-hydroxy[(methylamino)methoxy]methyl]phenol 4-[(R)-hydroxy[(methylamino)methoxy]methyl]phenol 94-07-5 CNCO[C@@H](O)C1=CC=C(O)C=C1 InChI=1S/C9H13NO3/c1-10-6-13-9(12)7-2-4-8(11)5-3-7/h2-5,9-12H,6H2,1H3/t9-/m1/s1 GBBBJHCSNNEWLH-SECBINFHSA-N belongs to the class of organic compounds known as 1-hydroxy-2-unsubstituted benzenoids. These are phenols that are unsubstituted at the 2-position. 1-hydroxy-2-unsubstituted benzenoids Organic compounds Benzenoids Phenols 1-hydroxy-2-unsubstituted benzenoids Aromatic homomonocyclic compounds Aromatic alcohols Benzene and substituted derivatives Dialkylamines Hemiacetals Hemiaminals Hydrocarbon derivatives Organopnictogen compounds 1-hydroxy-2-unsubstituted benzenoid Amine Aromatic alcohol Aromatic homomonocyclic compound Hemiacetal Hemiaminal Hydrocarbon derivative Monocyclic benzene moiety Organic nitrogen compound Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Secondary aliphatic amine Secondary amine Solid logp -0.73 ALOGPS logs -0.59 ALOGPS solubility 4.69e+01 g/l ALOGPS melting_point Mp 162-164° dec. logp 0.74 ChemAxon pka_strongest_acidic 9.46 ChemAxon pka_strongest_basic 8.13 ChemAxon iupac 4-[(R)-hydroxy[(methylamino)methoxy]methyl]phenol ChemAxon average_mass 183.2044 ChemAxon mono_mass 183.089543287 ChemAxon smiles CNCO[C@@H](O)C1=CC=C(O)C=C1 ChemAxon formula C9H13NO3 ChemAxon inchi InChI=1S/C9H13NO3/c1-10-6-13-9(12)7-2-4-8(11)5-3-7/h2-5,9-12H,6H2,1H3/t9-/m1/s1 ChemAxon inchikey GBBBJHCSNNEWLH-SECBINFHSA-N ChemAxon polar_surface_area 61.72 ChemAxon refractivity 48.17 ChemAxon polarizability 19.44 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 4 ChemAxon donor_count 3 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon HMDB04826 119 #<Reference:0x000055ce3189f8a0> #<Reference:0x000055ce3189f6e8> Citrus Unknown generic Fruits Unknown generic Lemon Type 1 specific Citrus limon 2708 Mandarin orange (Clementine, Tangerine) Type 1 specific Citrus reticulata 85571 Sweet orange Type 1 specific Citrus sinensis 2711 Alpha-2A adrenergic receptor P08913 ADRA2A Alpha-2B adrenergic receptor P18089 ADRA2B Cancer preventive 754 A substance that inhibits or prevents the proliferation of neoplasms. Cardiovascular 773 A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. Hypertensive 1007 Oxytocic 1185 A drug that stimulates contraction of the myometrium. Oxytocics are used to induce labour, obstetric at term, to prevent or control postpartum or postabortion haemorrhage, and to assess foetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (abortifacients). Vasoconstrictor 1412 Drug used to cause constriction of the blood vessels.