1.0 2010-04-08 22:04:41 UTC 2019-11-26 02:55:16 UTC FDB000717 N-gamma-L-Glutamyl-L-tyrosine Isolated from the seeds of Glycine max (soybean) Gamma-Glutamyltyrosine is made of glutamic acid and tyrosine. o-Tyrosine is a normal human metabolite. Its presence is possible due to the hydroxylation of l-phenylalanine by hydroxyl radical (*OH), and is proposed as an hydroxy radical biomarker of oxidative damage to proteins. o-Tyrosine might also be included in the diet and absorbed. It has been associated with disease such as Kwashiorkor, a severe form of protein-energy malnutrition. However, many publications mention that the results are inconclusive, and o-tyrosine is not selectively altered by antioxidant intervention, exercise training or age. (PMID: 14670743, 10969271, 9887186). N-gamma-L-Glutamyl-L-tyrosine is found in pulses. g-Glutamyltyrosine Gamma-glutamyltyrosine N-l-gamma-glutamyl-l-tyrosine γ-glutamyltyrosine C14H18N2O6 310.3025 310.116486318 2-amino-4-{[1-carboxy-2-(4-hydroxyphenyl)ethyl]carbamoyl}butanoic acid 2-amino-4-{[1-carboxy-2-(4-hydroxyphenyl)ethyl]carbamoyl}butanoic acid 7432-23-7 NC(CCC(=O)NC(CC1=CC=C(O)C=C1)C(O)=O)C(O)=O InChI=1S/C14H18N2O6/c15-10(13(19)20)5-6-12(18)16-11(14(21)22)7-8-1-3-9(17)4-2-8/h1-4,10-11,17H,5-7,15H2,(H,16,18)(H,19,20)(H,21,22) VVLXCWVSSLFQDS-UHFFFAOYSA-N belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. Dipeptides Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Aromatic homomonocyclic compounds 1-hydroxy-2-unsubstituted benzenoids Alpha amino acids Amino acids Amphetamines and derivatives Carbonyl compounds Carboxylic acids Dicarboxylic acids and derivatives Gamma-glutamyl amino acids Glutamine and derivatives Hydrocarbon derivatives Monoalkylamines N-acyl amines N-acyl-alpha amino acids Organic oxides Organopnictogen compounds Phenylalanine and derivatives Phenylpropanoic acids Secondary carboxylic acid amides Tyrosine and derivatives 1-hydroxy-2-unsubstituted benzenoid 3-phenylpropanoic-acid Alpha-amino acid Alpha-amino acid or derivatives Alpha-dipeptide Amine Amino acid Amino acid or derivatives Amphetamine or derivatives Aromatic homomonocyclic compound Benzenoid Carbonyl group Carboxamide group Carboxylic acid Dicarboxylic acid or derivatives Fatty acyl Fatty amide Gamma-glutamyl alpha-amino acid Glutamine or derivatives Hydrocarbon derivative Monocyclic benzene moiety N-acyl-alpha amino acid or derivatives N-acyl-alpha-amino acid N-acyl-amine Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenol Phenylalanine or derivatives Primary aliphatic amine Primary amine Secondary carboxylic acid amide Tyrosine or derivatives Solid logp -2.30 ALOGPS logs -2.50 ALOGPS solubility 9.87e-01 g/l ALOGPS melting_point Mp 221-222° dec. logp -2.5 ChemAxon pka_strongest_acidic 1.81 ChemAxon pka_strongest_basic 9.1 ChemAxon iupac 2-amino-4-{[1-carboxy-2-(4-hydroxyphenyl)ethyl]carbamoyl}butanoic acid ChemAxon average_mass 310.3025 ChemAxon mono_mass 310.116486318 ChemAxon smiles NC(CCC(=O)NC(CC1=CC=C(O)C=C1)C(O)=O)C(O)=O ChemAxon formula C14H18N2O6 ChemAxon inchi InChI=1S/C14H18N2O6/c15-10(13(19)20)5-6-12(18)16-11(14(21)22)7-8-1-3-9(17)4-2-8/h1-4,10-11,17H,5-7,15H2,(H,16,18)(H,19,20)(H,21,22) ChemAxon inchikey VVLXCWVSSLFQDS-UHFFFAOYSA-N ChemAxon polar_surface_area 149.95 ChemAxon refractivity 75.18 ChemAxon polarizability 30.63 ChemAxon rotatable_bond_count 8 ChemAxon acceptor_count 7 ChemAxon donor_count 5 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 88209 Specdb::MsMs 88210 Specdb::MsMs 88211 Specdb::MsMs 150900 Specdb::MsMs 150901 Specdb::MsMs 150902 HMDB11741 #<Reference:0x000055ce31e530a8> #<Reference:0x000055ce31e52ef0> #<Reference:0x000055ce31e52d38> Pulses Unknown generic