1.0 2010-04-08 22:04:48 UTC 2025-11-18 22:27:18 UTC FDB001018 Etidronic acid Food contaminant arising from its use as a boiler water additive for prepn. of steam used in food processing. Component of antimicrobial washes for poultry carcasses and fruit Etidronic acid is a first generation (non-nitrogenous) bisphosphonate in the same family as clodronate and tiludronate. Etidronic acid affects calcium metabolism and inhibits bone resorption and soft tissue calcification. Of the etidronic acid that is resorbed (from oral preparation) or infused (for intravenous drugs), about 50% is excreted unchanged by the kidney. The remainder has a very high affinity for bone tissue, and is rapidly absorbed onto the bone surface. Etidronic acid has been shown to prevent or delay skeletal-related events and decrease bone pain as well as normalize calcium levels in the presence of hypercalcemia. (1-hydroxy-1-phosphonoethyl)phosphonic acid (1-hydroxyethane-1,1-diyl)bis(phosphonic acid) (1-Hydroxyethylene)dionate (1-Hydroxyethylene)dionic acid (1-Hydroxyethylene)diphosphonic acid (1-Hydroxyethylidene)bis(onate) (1-Hydroxyethylidene)bis(onic acid) (1-Hydroxyethylidene)bis(phosphonic acid) (1-Hydroxyethylidene)bisonate (1-Hydroxyethylidene)bisonic acid (1-Hydroxyethylidene)bisphosphonic acid (1-Hydroxyethylidene)bisphosphonic acid, 9CI (1-Hydroxyethylidene)dionate (1-Hydroxyethylidene)dionic acid (1-Hydroxyethylidene)diphoshonic acid (1-Hydroxyethylidene)diphosphonic acid (Hydroxyethylidene)dionate (Hydroxyethylidene)dionic acid (hydroxyethylidene)diphosphonic acid 1-Hydroxy-1,1-dionoethane 1-Hydroxy-1,1-diphosphonoethane 1-Hydroxyethane-1, 1-bisphosphonic acid 1-Hydroxyethane-1,1-bisonate 1-Hydroxyethane-1,1-bisonic acid 1-Hydroxyethane-1,1-bisphosphonic acid 1-Hydroxyethane-1,1-dionate 1-Hydroxyethane-1,1-dionic acid 1-Hydroxyethane-1,1-diphosphonate 1-Hydroxyethane-1,1-diphosphonic acid 1-Hydroxyethane-1,1,-diphosphonic acid 1-Hydroxyethanedionate 1-Hydroxyethanedionic acid 1-Hydroxyethanediphosphonic acid 1-Hydroxyethylidene-1, 1-diphosphonic acid 1-Hydroxyethylidene-1,1-biphosphonate 1-Hydroxyethylidene-1,1-bisonate 1-Hydroxyethylidene-1,1-bisonic acid 1-Hydroxyethylidene-1,1-bisphosphonate 1-Hydroxyethylidene-1,1-dionate 1-Hydroxyethylidene-1,1-dionic acid 1-Hydroxyethylidene-1,1-diphosphonic acid 1-Hydroxyethylidenediphosphonic acid 1,1,1-Ethanetriol dionate 1,1,1-Ethanetriol dionic acid 1,1,1-Ethanetriol diphosphonate Acetodionate Acetodionic acid Acetodiphosphonic acid Acide etidronique Acido etidronico Acidum etidronicum Dequest 2010 Dequest 2015 Dequest Z 010 Diphosphonate (base) EHDP Ethane-1-hydroxy-1, 1-diphosphonate Ethane-1-hydroxy-1,1-bisonate Ethane-1-hydroxy-1,1-bisonic acid Ethane-1-hydroxy-1,1-bisphosphonate Ethane-1-hydroxy-1,1-dionate Ethane-1-hydroxy-1,1-dionic acid Ethane-1-hydroxy-1,1-diphosphonate Ethane-1-hydroxy-1,1-diphosphonic acid Etidronate Etidronate disodium Etidronic acid Etidronic acid (usan/inn) Etidronic acid [usan:inn:ban] Etidronic acid monohydrate Etidronic acid, BAN, INN, USAN Etidronic acid(usan) Etidronsaeure Ferrofos 510 HEBP HEDP Hydroxyethane-1,1-diphosphonic acid Hydroxyethanedionate Hydroxyethanedionic acid Hydroxyethanediphosphonic acid Ksidifon Oxyethylidenedionate Oxyethylidenedionic acid Oxyethylidenediphosphonic acid Phosphonic acid, (1-hydroxyethylidene)bis- Phosphonic acid, (1-hydroxyethylidene)di- Phosphonic acid, 1-hydroxy-1,1-ethanediyl ester Phosphonic acid, P,P'-(1-hydroxyethylidene)bis- Turpinal SL Xidiphone C2H8O7P2 206.027 205.974526594 (1-hydroxy-1-phosphonoethyl)phosphonic acid etidronic acid 7414-83-7 CC(O)(P(O)(O)=O)P(O)(O)=O InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9) DBVJJBKOTRCVKF-UHFFFAOYSA-N belongs to the class of organic compounds known as bisphosphonates. These are organic compounds containing two phosphonate groups linked together through a carbon atoms. Bisphosphonates Organic compounds Organic acids and derivatives Organic phosphonic acids and derivatives Bisphosphonates Aliphatic acyclic compounds Hydrocarbon derivatives Organic oxides Organic phosphonic acids Organooxygen compounds Organophosphorus compounds Organopnictogen compounds Aliphatic acyclic compound Bisphosphonate Hydrocarbon derivative Organic oxide Organic oxygen compound Organooxygen compound Organophosphonic acid Organophosphorus compound Organopnictogen compound 1,1-bis(phosphonic acid) Solid logp -0.77 ALOGPS logs -1.25 ALOGPS solubility 1.15e+01 g/l ALOGPS melting_point Mp 105° logp -2.3 ChemAxon pka_strongest_acidic 0.7 ChemAxon pka_strongest_basic -5.1 ChemAxon iupac (1-hydroxy-1-phosphonoethyl)phosphonic acid ChemAxon average_mass 206.027 ChemAxon mono_mass 205.974526594 ChemAxon smiles CC(O)(P(O)(O)=O)P(O)(O)=O ChemAxon formula C2H8O7P2 ChemAxon inchi InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9) ChemAxon inchikey DBVJJBKOTRCVKF-UHFFFAOYSA-N ChemAxon polar_surface_area 135.29 ChemAxon refractivity 34.51 ChemAxon polarizability 13.97 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 7 ChemAxon donor_count 5 ChemAxon physiological_charge -3 ChemAxon formal_charge 0 ChemAxon Specdb::MsIr 3202 Specdb::MsIr 3203 Specdb::MsIr 3204 Specdb::NmrOneD 12802 Specdb::NmrOneD 12803 Specdb::NmrOneD 12804 Specdb::NmrOneD 12805 Specdb::NmrOneD 12806 Specdb::NmrOneD 12807 Specdb::NmrOneD 12808 Specdb::NmrOneD 12809 Specdb::NmrOneD 12810 Specdb::NmrOneD 12811 Specdb::NmrOneD 12812 Specdb::NmrOneD 12813 Specdb::NmrOneD 12814 Specdb::NmrOneD 12815 Specdb::NmrOneD 12816 Specdb::NmrOneD 12817 Specdb::NmrOneD 12818 Specdb::NmrOneD 12819 Specdb::NmrOneD 12820 Specdb::NmrOneD 12821 Specdb::CMs 12056 Specdb::CMs 40608 Specdb::CMs 168176 Specdb::MsMs 90225 Specdb::MsMs 90226 Specdb::MsMs 90227 Specdb::MsMs 153330 Specdb::MsMs 153331 Specdb::MsMs 153332 Specdb::MsMs 437614 Specdb::MsMs 437615 Specdb::MsMs 437616 Specdb::MsMs 437617 Specdb::MsMs 437618 Specdb::MsMs 3220330 Specdb::MsMs 3220331 Specdb::MsMs 3220332 Specdb::MsMs 3220333 Specdb::MsMs 3220334 Specdb::MsMs 3220335 HMDB15210 911 Receptor-type tyrosine-protein phosphatase S Q13332 PTPRS V-type proton ATPase catalytic subunit A P38606 ATP6V1A