1.0 2010-04-08 22:04:49 UTC 2025-11-18 22:27:55 UTC FDB001083 Bromelains Enzymes occurring in pineapple juice (Ananas sativus); used in tenderising meat and chill-proofing beer [DFC] Along with papain, bromelain is one of the most popular substances to use for meat tenderizing.; Bromelain can refer to one of two protease enzymes extracted from the plant family Bromeliaceae, or it can refer to a combination of those enzymes along with other compounds produced in an extract. [BioSpider]. Bromelains is found in pineapple and fruits. Ananase Bromelase E.C. 3.4.22.32 (stem bromelain) E.C. 3.4.22.33 (fruit bromelain) Extranase Inflamen Traumanase C11H17N2NaO3 248.254 248.113687095 sodium 5-ethyl-6-hydroxy-2-oxo-5-(pentan-2-yl)-2,5-dihydropyrimidin-4-olate sodium 5-ethyl-6-hydroxy-2-oxo-5-(pentan-2-yl)pyrimidin-4-olate 9001-00-7 [Na+].CCCC(C)C1(CC)C(O)=NC(=O)N=C1[O-] InChI=1S/C11H18N2O3.Na/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);/q;+1/p-1 QGMRQYFBGABWDR-UHFFFAOYSA-M belongs to the class of organic compounds known as barbituric acid derivatives. Barbituric acid derivatives are compounds containing a perhydropyrimidine ring substituted at C-2, -4 and -6 by oxo groups. Barbituric acid derivatives Organic compounds Organoheterocyclic compounds Diazines Pyrimidines and pyrimidine derivatives Aliphatic heteromonocyclic compounds Azacyclic compounds Carbene-type 1,3-dipolar compounds Carbonyl compounds Diazinanes Dicarboximides Hydrocarbon derivatives N-acyl ureas Organic oxides Organic sodium salts Organonitrogen compounds Organopnictogen compounds 1,3-diazinane Aliphatic heteromonocyclic compound Azacycle Barbiturate Carbene-type 1,3-dipolar compound Carbonic acid derivative Carbonyl group Carboxylic acid derivative Dicarboximide Hydrocarbon derivative N-acyl urea Organic 1,3-dipolar compound Organic alkali metal salt Organic nitrogen compound Organic oxide Organic oxygen compound Organic salt Organic sodium salt Organonitrogen compound Organooxygen compound Organopnictogen compound Ureide organic molecular entity logp 2.22 ALOGPS logs -3.00 ALOGPS solubility 2.48e-01 g/l ALOGPS logp 2.63 ChemAxon pka_strongest_acidic 5.74 ChemAxon pka_strongest_basic -4 ChemAxon iupac sodium 5-ethyl-6-hydroxy-2-oxo-5-(pentan-2-yl)-2,5-dihydropyrimidin-4-olate ChemAxon average_mass 248.254 ChemAxon mono_mass 248.113687095 ChemAxon smiles [Na+].CCCC(C)C1(CC)C(O)=NC(=O)N=C1[O-] ChemAxon formula C11H17N2NaO3 ChemAxon inchi InChI=1S/C11H18N2O3.Na/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);/q;+1/p-1 ChemAxon inchikey QGMRQYFBGABWDR-UHFFFAOYSA-M ChemAxon polar_surface_area 85.08 ChemAxon refractivity 69.2 ChemAxon polarizability 22.83 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 5 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 1316155 Specdb::MsMs 1316156 Specdb::MsMs 1316157 Specdb::MsMs 1430617 Specdb::MsMs 1430618 Specdb::MsMs 1430619 Fruits Unknown generic Pineapple Type 1 specific Ananas comosus 4615 Analgesic 56 An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. Anorectic 67 An agent which regulates the physiologic mechanisms that control the appetite and food intake. Anti anginal 114 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti bacterial 145 A substance that kills or slows the growth of bacteria. Anti cellulitic 170 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti dysmenorrheic 241 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti dyspeptic 242 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti ecchymotic 246 Anti episiotomic 266 Anti leukemic 393 A substance that inhibits or prevents the proliferation of neoplasms. Anti metastatic 434 A substance that inhibits or prevents the proliferation of neoplasms. Anti proliferant 547 Anti prostaglandin 550 A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. Anti thrombophlebitic 649 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti thrombotic 650 Drug that acts on blood and blood-forming organs and those that affect the hemostatic system. Anti ulcer 676 One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. Anti-aggregant 94 Anti-appetant 126 An agent which regulates the physiologic mechanisms that control the appetite and food intake. Anti-arthritic 131 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-bronchitic 154 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-edemic 248 Anti-infective 368 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-inflammatory 370 A substance that reduces or suppresses inflammation. Anti-plaque 531 Anti-pneumonic 535 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-radiation 571 Anti-sclerodermic 595 A drug used to treat or prevent skin disorders or for the routine care of skin. Anti-sinusitic 617 Anti-spasmodic 619 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-tussive 674 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Antitumor 672 A substance that inhibits or prevents the proliferation of neoplasms. Chemopreventive 796 A substance that inhibits or prevents the proliferation of neoplasms. Chitinolytic 798 Chitosanolytic 799 Differentiator 880 Digestive 881 Emetic 899 Fibrinolytic 932 Hypotensive 1021 Laxative 1065 An agent that produces a soft formed stool, and relaxes and loosens the bowels, typically used over a protracted period, to relieve constipation. Compare with cathartic, which is a substance that accelerates defecation. A substances can be both a laxative and a cathartic. Lipolytic 1074 Mucolytic 1122 A compound that alters the structure of mucus so as to decrease its viscosity and thereby facilitate its removal by ciliary action and expectoration. Compare with antitussives, which suppress the cough reflex, and expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing. Myorelaxant 1134 Nematicide 1141 A substance used to destroy pests of the phylum Nematoda (roundworms). Pesticide 1210 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. Proliferant 1251 Prostaglandin-synthetase inhibitor 1259 A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. Proteolytic 1265 Vermifuge 1422 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. Vulnerary 1430 A drug used in treating and healing of wounds.