1.0 2010-04-08 22:04:50 UTC 2019-11-26 02:55:55 UTC FDB001108 (S)-[6]-Gingerol Constituent of ginger Zingiber officinale. (S)-[6]-Gingerol is found in many foods, some of which are caraway, star anise, cumin, and ginger. (+)-[6]-Gingerol (5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one (S)-(+)-[6]-Gingerol (S)-(+)-[6]Gingerol (S)-6-Gingerol [6]-Gingerol 3-Decanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (S)- 5-Hydroxy-1-(4-hydroxy-3-methoxtphenyl)-3-decanone 5-Hydroxy-1-(4-hydroxy-3-methoxycyclohexyl)decan-3-one 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone 6-Gingerol Gingerol C17H26O4 294.3859 294.18310932 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one gingerol 58253-27-3 CCCCCC(O)CC(=O)CCC1=CC=C(O)C(OC)=C1 InChI=1S/C17H26O4/c1-3-4-5-6-14(18)12-15(19)9-7-13-8-10-16(20)17(11-13)21-2/h8,10-11,14,18,20H,3-7,9,12H2,1-2H3 NLDDIKRKFXEWBK-UHFFFAOYSA-N belongs to the class of organic compounds known as gingerols. Gingerols are compounds containing a gingerol moiety, which is structurally characterized by a 4-hydroxy-3-methoxyphenyl group substituted at the C6 carbon atom by a 5-hydroxy-alkane-3-one. Gingerols Organic compounds Benzenoids Phenols Methoxyphenols Aromatic homomonocyclic compounds 1-hydroxy-2-unsubstituted benzenoids Alkyl aryl ethers Anisoles Beta-hydroxy ketones Fatty alcohols Hydrocarbon derivatives Methoxybenzenes Organic oxides Phenoxy compounds Secondary alcohols 1-hydroxy-2-unsubstituted benzenoid Alcohol Alkyl aryl ether Anisole Aromatic homomonocyclic compound Beta-hydroxy ketone Carbonyl group Ether Fatty acyl Fatty alcohol Gingerol Hydrocarbon derivative Ketone Methoxybenzene Monocyclic benzene moiety Organic oxide Organic oxygen compound Organooxygen compound Phenol ether Phenoxy compound Secondary alcohol a phenylpropanoid Solid logp 3.45 ALOGPS logs -3.57 ALOGPS solubility 7.96e-02 g/l ALOGPS melting_point 31 oC logp 3.62 ChemAxon pka_strongest_acidic 9.95 ChemAxon pka_strongest_basic -2.8 ChemAxon iupac 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one ChemAxon average_mass 294.3859 ChemAxon mono_mass 294.18310932 ChemAxon smiles CCCCCC(O)CC(=O)CCC1=CC=C(O)C(OC)=C1 ChemAxon formula C17H26O4 ChemAxon inchi InChI=1S/C17H26O4/c1-3-4-5-6-14(18)12-15(19)9-7-13-8-10-16(20)17(11-13)21-2/h8,10-11,14,18,20H,3-7,9,12H2,1-2H3 ChemAxon inchikey NLDDIKRKFXEWBK-UHFFFAOYSA-N ChemAxon polar_surface_area 66.76 ChemAxon refractivity 83.11 ChemAxon polarizability 33.76 ChemAxon rotatable_bond_count 10 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 17191 Specdb::CMs 28718 Specdb::CMs 38884 Specdb::CMs 99876 Specdb::CMs 153745 Specdb::MsMs 50961 Specdb::MsMs 50962 Specdb::MsMs 50963 Specdb::MsMs 158097 Specdb::MsMs 158098 Specdb::MsMs 158099 Specdb::MsMs 449247 Specdb::MsMs 449248 Specdb::MsMs 449249 Specdb::MsMs 449250 Specdb::MsMs 449251 Specdb::MsMs 2235653 Specdb::MsMs 2237733 Specdb::MsMs 2237775 Specdb::MsMs 2239779 Specdb::MsMs 2239935 Specdb::MsMs 2362277 Specdb::MsMs 2362278 Specdb::MsMs 2362279 Specdb::MsMs 2600033 Specdb::MsMs 2600034 Specdb::MsMs 2600035 HMDB05783 Caraway Type 1 specific Carum carvi 48032 0.0 0.0 0.0 mg/100 g Ceylon cinnamon Type 1 specific Cinnamomum verum 128608 0.0 0.0 0.0 mg/100 g Cloves Type 1 specific Syzygium aromaticum 219868 0.0 0.0 0.0 mg/100 g Cumin Type 1 specific Cuminum cyminum 52462 0.0 0.0 0.0 mg/100 g Ginger Type 1 specific Zingiber officinale 94328 187.300003 187.300003052 187.300003052 mg/100 g Herbs and Spices Unknown generic Nutmeg Type 1 specific Myristica fragrans 51089 0.0 0.0 0.0 mg/100 g Pepper (Spice) Type 1 specific Piper nigrum 13216 0.0 0.0 0.0 mg/100 g Star anise Type 1 specific Illicium verum 124778 0.0 0.0 0.0 mg/100 g Sweet bay Type 1 specific Laurus nobilis 85223 0.0 0.0 0.0 mg/100 g pungent Amphitensive 53 Analgesic 56 An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. Anti 5-hydroxytryptamine 73 Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. Anti emetic 253 A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors. Anti hepatotoxic 328 Any compound that is able to prevent damage to the liver. Anti histaminic 331 Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Anti prostaglandin 550 A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. Anti pyretic 567 A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. Anti schistosomiac 593 A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. Anti septic 603 A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. Anti seratogenic 605 Anti thromboxane 651 A substance that diminishes the rate of a chemical reaction. Anti ulcer 676 One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. Anti-aggregant 94 Anti-allergic 103 A drug used to treat allergic reactions. Anti-inflammatory 370 A substance that reduces or suppresses inflammation. Anti-oxidant 502 A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324. Anti-tussive 674 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Cancer preventive 754 A substance that inhibits or prevents the proliferation of neoplasms. Cardiodepressant 766 A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. Cardiotonic 771 A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. Cholagogue 800 Cyclooxygenase inhibitor 849 A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. Depressor 873 Fungicide 940 A substance used to destroy fungal pests. Gastrostimulant 949 A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion. Hepatoprotective 981 Any compound that is able to prevent damage to the liver. Hypertensive 1007 Hypotensive 1021 Inotropic 1037 Larvicide 1063 Molluscicide 1113 A substance used to destroy pests of the phylum Mollusca. Mutagenic 1125 Nematicide 1141 A substance used to destroy pests of the phylum Nematoda (roundworms). Pesticide 1210 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. Prostaglandin synthesis inhibitor 1258 A substance that diminishes the rate of a chemical reaction. Sedative 1311 A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. Thermogenic 1355