1.0 2010-04-08 22:04:58 UTC 2025-11-18 22:31:24 UTC FDB001461 6-Oxocamphor 6-oxocamphor, also known as topotecan or hycamtin, is a member of the class of compounds known as camptothecins. Camptothecins are heterocyclic compounds comprising a planar pentacyclic ring structure, that includes a pyrrolo[3,4-beta]-quinoline moiety (rings A, B and C), conjugated pyridone moiety (ring D) and one chiral center at position 20 within the alpha-hydroxy lactone ring with (S) configuration (the E-ring). 6-oxocamphor can be found in common sage, which makes 6-oxocamphor a potential biomarker for the consumption of this food product. 9-Dimethylaminomethyl-10-hydroxycamptothecin, HCl salt Evotropin Hycamptamine Hycamptamine hydrochloride Hycamtin Hycamtin (TN) Nogitecan hydrochloride Nogitecan hydrochloride (jan) Topotecan Topotecan HCL Topotecan hydrochloride Topotecan hydrochloride (usan) Topotecan hydrochloride [usan] Topotecan monohydrochloride C23H24ClN3O5 457.907 457.1404486 (19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione hydrochloride topotecan hydrochloride 1935-17-7 Cl.CC[C@@]1(O)C(=O)OCC2=C1C=C1N(CC3=C1N=C1C=CC(O)=C(CN(C)C)C1=C3)C2=O InChI=1S/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1 DGHHQBMTXTWTJV-BQAIUKQQSA-N belongs to the class of organic compounds known as camptothecins. These are heterocyclic compounds comprising a planar pentacyclic ring structure, that includes a pyrrolo[3,4-beta]-quinoline moiety (rings A, B and C), conjugated pyridone moiety (ring D) and one chiral center at position 20 within the alpha-hydroxy lactone ring with (S) configuration (the E-ring). Camptothecins Organic compounds Alkaloids and derivatives Camptothecins Aromatic heteropolycyclic compounds 1-hydroxy-2-unsubstituted benzenoids Amino acids and derivatives Aralkylamines Azacyclic compounds Carbonyl compounds Carboxylic acid esters Heteroaromatic compounds Hydrocarbon derivatives Hydrochlorides Hydroxyquinolines Lactams Lactones Monocarboxylic acids and derivatives Organic oxides Organopnictogen compounds Oxacyclic compounds Pyranopyridines Pyridinones Tertiary alcohols Trialkylamines 1-hydroxy-2-unsubstituted benzenoid Alcohol Amine Amino acid or derivatives Aralkylamine Aromatic heteropolycyclic compound Azacycle Benzenoid Camptothecin Carbonyl group Carboxylic acid derivative Carboxylic acid ester Heteroaromatic compound Hydrocarbon derivative Hydrochloride Hydroxyquinoline Lactam Lactone Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Pyranopyridine Pyridine Pyridinone Quinoline Tertiary alcohol Tertiary aliphatic amine Tertiary amine logp -0.36 ChemAxon pka_strongest_acidic 8 ChemAxon pka_strongest_basic 9.83 ChemAxon iupac (19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione hydrochloride ChemAxon average_mass 457.907 ChemAxon mono_mass 457.1404486 ChemAxon smiles Cl.CC[C@@]1(O)C(=O)OCC2=C1C=C1N(CC3=C1N=C1C=CC(O)=C(CN(C)C)C1=C3)C2=O ChemAxon formula C23H24ClN3O5 ChemAxon inchi InChI=1S/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1 ChemAxon inchikey DGHHQBMTXTWTJV-BQAIUKQQSA-N ChemAxon polar_surface_area 103.2 ChemAxon refractivity 115.02 ChemAxon polarizability 44.85 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 6 ChemAxon donor_count 2 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 78414 Specdb::MsMs 78415 Specdb::MsMs 78416 Specdb::MsMs 138759 Specdb::MsMs 138760 Specdb::MsMs 138761 Specdb::MsMs 450599 Common sage Type 1 specific Salvia officinalis 38868