1.0 2010-04-08 22:05:15 UTC 2025-11-18 22:35:05 UTC FDB002122 (S)-Corydine (s)-corydine, also known as corydine hydrochloride or corydine, (R)-isomer, is a member of the class of compounds known as aporphines. Aporphines are quinoline alkaloids containing the dibenzo[de,g]quinoline ring system or a dehydrogenated derivative thereof (s)-corydine is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). (s)-corydine can be found in barley and custard apple, which makes (s)-corydine a potential biomarker for the consumption of these food products. (S)-(+)-corydine 6a-alpha-Aporphin-1-ol, 2,10,11-trimethoxy- D-Corydine S-1-Hydroxy-2,10,11-trimethoxyaporphine S-Glaucentrine C20H23NO4 341.4009 341.162708229 (9S)-3,4,15-trimethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(17),2,4,6,13,15-hexaen-16-ol (9S)-3,4,15-trimethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(17),2,4,6,13,15-hexaen-16-ol 476-69-7 [H][C@]12CC3=CC=C(OC)C(OC)=C3C3=C1C(CCN2C)=CC(OC)=C3O InChI=1S/C20H23NO4/c1-21-8-7-12-10-15(24-3)19(22)18-16(12)13(21)9-11-5-6-14(23-2)20(25-4)17(11)18/h5-6,10,13,22H,7-9H2,1-4H3/t13-/m0/s1 IDQUPXZJURZAGF-ZDUSSCGKSA-N belongs to the class of organic compounds known as aporphines. These are quinoline alkaloids containing the dibenzo[de,g]quinoline ring system or a dehydrogenated derivative thereof. Aporphines Organic compounds Alkaloids and derivatives Aporphines Aromatic heteropolycyclic compounds Alkyl aryl ethers Anisoles Aralkylamines Azacyclic compounds Benzoquinolines Hydrocarbon derivatives Naphthols and derivatives Organopnictogen compounds Phenanthrenes and derivatives Tetrahydroisoquinolines Trialkylamines 1-naphthol Alkyl aryl ether Amine Anisole Aporphine Aralkylamine Aromatic heteropolycyclic compound Azacycle Benzenoid Benzoquinoline Ether Hydrocarbon derivative Naphthalene Organic nitrogen compound Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenanthrene Quinoline Tertiary aliphatic amine Tertiary amine Tetrahydroisoquinoline logp 2.84 ALOGPS logs -3.51 ALOGPS solubility 1.05e-01 g/l ALOGPS melting_point Mp 149° logp 2.92 ChemAxon pka_strongest_acidic 9.98 ChemAxon pka_strongest_basic 6.62 ChemAxon iupac (9S)-3,4,15-trimethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(17),2,4,6,13,15-hexaen-16-ol ChemAxon average_mass 341.4009 ChemAxon mono_mass 341.162708229 ChemAxon smiles [H][C@]12CC3=CC=C(OC)C(OC)=C3C3=C1C(CCN2C)=CC(OC)=C3O ChemAxon formula C20H23NO4 ChemAxon inchi InChI=1S/C20H23NO4/c1-21-8-7-12-10-15(24-3)19(22)18-16(12)13(21)9-11-5-6-14(23-2)20(25-4)17(11)18/h5-6,10,13,22H,7-9H2,1-4H3/t13-/m0/s1 ChemAxon inchikey IDQUPXZJURZAGF-ZDUSSCGKSA-N ChemAxon polar_surface_area 51.16 ChemAxon refractivity 97.4 ChemAxon polarizability 37.56 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 5 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 104787 Specdb::MsMs 104788 Specdb::MsMs 104789 Specdb::MsMs 171132 Specdb::MsMs 171133 Specdb::MsMs 171134 Specdb::MsMs 3599050 Specdb::MsMs 3599051 Specdb::MsMs 3599052 Specdb::MsMs 3599053 Specdb::MsMs 3599054 Specdb::MsMs 3599055 Barley Type 1 specific Hordeum vulgare 4513 Custard apple Type 1 specific Annona reticulata 301862