1.0 2010-04-08 22:05:20 UTC 2019-11-26 02:57:21 UTC FDB002353 Ampicillin Potential contaminant of cow's milk arising from its veterinary use Ampicillin is a beta-lactam antibiotic that has been used extensively to treat bacterial infections since 1961. It is considered part of the aminopenicillin family and is roughly equivalent to amoxicillin in terms of spectrum and level of activity. Ampicillin is found in milk and milk products and common pea. (2S,5R,6R)-6-[[(2R)-2-amino-2-Phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylethanoyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylethanoyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylIC ACID α-aminobenzylpenicillin 6-(a-Aminophenylacetamido)penicillanic acid 6-(D-(2-amino-2-Phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate 6-(D-(2-amino-2-Phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 6-(D(-)-alpha-Aminophenylacetamido)penicillanic acid 6-[(Aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 9CI 6-D(-)-α-Aminophenylacetamido-penicillanic acid 6-D(-)-alpha-Aminophenylacetamido-penicillanic acid ABPC Acillin Adobacillin Alpen alpha-Aminobenzylpenicillin Amblosin Amcill Amfipen Amfipen v Aminobenzylpenicillin Amipenix s AMP Ampen AMPI Ampi-bol Ampi-co Ampi-tab Ampichel Ampicil Ampicilina Ampicillin (usan) Ampicillin (usp/inn) Ampicillin [usan:ban:inn:jan] Ampicillin a Ampicillin acid Ampicillin anhydrate Ampicillin anhydrous Ampicillin base Ampicillin sodium Ampicillin trihydrate Ampicillina Ampicilline Ampicillinum Ampifarm Ampikel Ampimed Ampipenin Ampiscel Ampisyn Ampivax Ampivet Amplacilina Amplin Amplipenyl Amplisom Amplital Anhydrous ampicillin Austrapen AY 6108 Bayer 5427 Binotal Bonapicillin Britacil BRL 1341 Campicillin Cimex Copharcilin D-(-)-α-aminobenzylpenicillin D-(-)-α-aminopenicillin D-(-)-6-(a-Aminophenylacetamido)penicillanate D-(-)-6-(a-Aminophenylacetamido)penicillanic acid D-(-)-6-(alpha-Aminophenylacetamido)penicillanate D-(-)-6-(alpha-aminophenylacetamido)penicillanic acid D-(-)-6-(α-aminophenylacetamido)penicillanate D-(-)-6-(α-aminophenylacetamido)penicillanic acid D-(-)-alpha-aminobenzylpenicillin D-(-)-alpha-aminopenicillin D-(-)-ampicillin D-a-Aminobenzylpenicillin D-ampicillin D-cillin Delcillin Deripen Divercillin Doktacillin Duphacillin Geocillin Grampenil Guicitrina Guicitrine KS-R1 Lifeampil Magnapen Marcillin Morepen Norobrittin Novo-ampicillin NSC 528986 Nuvapen Olin kid Omnipen Orbicilina Pen a Pen ampil Penbristol Penbritin Penbrock Penicline Penimic Pensyn Pentrex Pentrexl Pentrexyl Pentritin Pfizerpen a Polycillin Ponecil Princillin Principen Qidamp Racenacillin Ro-ampen Rosampline Roscillin Semicillin Servicillin SK-ampicillin Sumipanto Supen Synpenin Texcillin Tokiocillin Tolomol Totacillin Totalciclina Totapen Trifacilina Ukapen Ultrabion Ultrabron Vampen Viccillin Vidocillin Vidopen Wypicil C16H19N3O4S 349.405 349.109626801 6-[(2-amino-1-hydroxy-2-phenylethylidene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6-[(2-amino-1-hydroxy-2-phenylethylidene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 69-53-4 CC1(C)SC2C(NC(=O)C(N)C3=CC=CC=C3)C(=O)N2C1C(O)=O InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23) AVKUERGKIZMTKX-UHFFFAOYSA-N belongs to the class of organic compounds known as n-acyl-alpha amino acids and derivatives. N-acyl-alpha amino acids and derivatives are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom. N-acyl-alpha amino acids and derivatives Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Aromatic heteropolycyclic compounds Amino acids Aralkylamines Azacyclic compounds Azetidines Benzene and substituted derivatives Carbonyl compounds Carboximidic acids Carboxylic acids Dialkylthioethers Hydrocarbon derivatives Monoalkylamines Monocarboxylic acids and derivatives Organic oxides Organopnictogen compounds Penams Propargyl-type 1,3-dipolar organic compounds Tertiary carboxylic acid amides Thiazolidines Thiohemiaminal derivatives Amine Amino acid Aralkylamine Aromatic heteropolycyclic compound Azacycle Azetidine Benzenoid Beta-lactam Carbonyl group Carboxamide group Carboximidic acid Carboximidic acid derivative Carboxylic acid Dialkylthioether Hemithioaminal Hydrocarbon derivative Lactam Monocarboxylic acid or derivatives Monocyclic benzene moiety N-acyl-alpha amino acid or derivatives Organic 1,3-dipolar compound Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Penam Primary aliphatic amine Primary amine Propargyl-type 1,3-dipolar organic compound Tertiary carboxylic acid amide Thiazolidine Thioether Solid logp 0.44 ALOGPS logs -3.03 ALOGPS solubility 3.25e-01 g/l ALOGPS melting_point Mp 199-202° dec. logp -1.4 ChemAxon pka_strongest_acidic 2.8 ChemAxon pka_strongest_basic 8.42 ChemAxon iupac 6-[(2-amino-1-hydroxy-2-phenylethylidene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ChemAxon average_mass 349.405 ChemAxon mono_mass 349.109626801 ChemAxon smiles CC1(C)SC2C(NC(=O)C(N)C3=CC=CC=C3)C(=O)N2C1C(O)=O ChemAxon formula C16H19N3O4S ChemAxon inchi InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23) ChemAxon inchikey AVKUERGKIZMTKX-UHFFFAOYSA-N ChemAxon polar_surface_area 116.22 ChemAxon refractivity 88.05 ChemAxon polarizability 35.47 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 6 ChemAxon donor_count 3 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon HMDB14559 28971 AIC #<Reference:0x000055ce3248f188> #<Reference:0x000055ce3248efd0> #<Reference:0x000055ce3248ee18> #<Reference:0x000055ce3248ec60> #<Reference:0x000055ce3248eaa8> Common pea Type 1 specific Pisum sativum 3888 Milk and milk products Unknown generic