1.0 2010-04-08 22:05:22 UTC 2025-11-18 22:37:28 UTC FDB002436 Fraxinol Fraxinol is a member of the class of compounds known as hydroxycoumarins. Hydroxycoumarins are coumarins that contain one or more hydroxyl groups attached to the coumarin skeleton. Fraxinol is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Fraxinol can be found in sour cherry, which makes fraxinol a potential biomarker for the consumption of this food product. 2H-1-Benzopyran-2-one, 6-hydroxy-5,7-dimethoxy- 5,7-Dimethoxy-6-hydroxycoumarin 6-Hydroxy-5,7-dimethoxy-2H-1-benzopyran-2-one, 9CI 6-Hydroxy-5,7-dimethoxycoumarin Fraxinol C11H10O5 222.1941 222.05282343 6-hydroxy-5,7-dimethoxy-2H-chromen-2-one 6-hydroxy-5,7-dimethoxychromen-2-one 486-28-2 COC1=C(O)C(OC)=C2C=CC(=O)OC2=C1 InChI=1S/C11H10O5/c1-14-8-5-7-6(3-4-9(12)16-7)11(15-2)10(8)13/h3-5,13H,1-2H3 PBPNOAHYDPHKFH-UHFFFAOYSA-N belongs to the class of organic compounds known as hydroxycoumarins. These are coumarins that contain one or more hydroxyl groups attached to the coumarin skeleton. Hydroxycoumarins Organic compounds Phenylpropanoids and polyketides Coumarins and derivatives Hydroxycoumarins Aromatic heteropolycyclic compounds 1-benzopyrans Alkyl aryl ethers Anisoles Heteroaromatic compounds Hydrocarbon derivatives Lactones Organic oxides Oxacyclic compounds Pyranones and derivatives 1-benzopyran Alkyl aryl ether Anisole Aromatic heteropolycyclic compound Benzenoid Benzopyran Ether Heteroaromatic compound Hydrocarbon derivative Hydroxycoumarin Lactone Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Pyran Pyranone logp 1.76 ALOGPS logs -2.15 ALOGPS solubility 1.59e+00 g/l ALOGPS melting_point Mp 171-172° logp 1.16 ChemAxon pka_strongest_acidic 9.29 ChemAxon pka_strongest_basic -4.6 ChemAxon iupac 6-hydroxy-5,7-dimethoxy-2H-chromen-2-one ChemAxon average_mass 222.1941 ChemAxon mono_mass 222.05282343 ChemAxon smiles COC1=C(O)C(OC)=C2C=CC(=O)OC2=C1 ChemAxon formula C11H10O5 ChemAxon inchi InChI=1S/C11H10O5/c1-14-8-5-7-6(3-4-9(12)16-7)11(15-2)10(8)13/h3-5,13H,1-2H3 ChemAxon inchikey PBPNOAHYDPHKFH-UHFFFAOYSA-N ChemAxon polar_surface_area 64.99 ChemAxon refractivity 56.46 ChemAxon polarizability 21.07 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 4 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 56863 Specdb::CMs 69019 Specdb::CMs 168714 Specdb::MsMs 78054 Specdb::MsMs 78055 Specdb::MsMs 78056 Specdb::MsMs 138306 Specdb::MsMs 138307 Specdb::MsMs 138308 Specdb::MsMs 2303550 Specdb::MsMs 2303551 Specdb::MsMs 2303552 Specdb::MsMs 3066017 Specdb::MsMs 3066018 Specdb::MsMs 3066019 Sour cherry Type 1 specific Prunus cerasus 140311 Aldose reductase inhibitor 40 An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21). Cancer preventive 754 A substance that inhibits or prevents the proliferation of neoplasms.