1.0 2010-04-08 22:05:28 UTC 2025-11-18 22:39:32 UTC FDB002680 Hesperidin Found in most citrus fruits and other members of the Rutaceae, also in Mentha longifolia Hesperidin is a flavanone glycoside (flavonoid) (C28H34O15) found abundantly in citrus fruits. Its aglycone form is called hesperetin. (2S)-Hesperidin (S)-(-)-Hesperidin 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2S)- Atripliside B Cirantin Ciratin Cirontin Flavanone, 3',5,7-trihydroxy-4'-methoxy-, 7-(6-O-a-L-rhamnosyl-D-glucoside) (7ci) Flavanone, 3',5,7-trihydroxy-4'-methoxy-, 7-(6-O-alpha-L-rhamnosyl-delta-glucoside) (7ci) Hesper bitabs Hesperetin 7-O-rhamnoglucoside Hesperetin 7-O-rutinoside Hesperetin 7-rhamnoglucoside Hesperetin 7-rutinoside Hesperetin-7-rutinoside Hesperetin-rutinoside Hesperidin Hesperidin, (2S)- Hesperidin, (S)-(-)- Hesperidine Hesperidoside Hesperitin-7-rhamnoglucoside C28H34O15 610.5606 610.189770418 (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-3,4-dihydro-2H-1-benzopyran-4-one hesperidin 520-26-3 COC1=CC=C(C=C1O)[C@@H]1CC(=O)C2=C(O1)C=C(O[C@@H]1O[C@H](CO[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]1O)C=C2O InChI=1S/C28H34O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-7,10,17,19,21-30,32-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1 QUQPHWDTPGMPEX-QJBIFVCTSA-N belongs to the class of organic compounds known as flavonoid-7-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position. Flavonoid-7-O-glycosides Organic compounds Phenylpropanoids and polyketides Flavonoids Flavonoid glycosides Aromatic heteropolycyclic compounds 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids 3'-hydroxyflavonoids 4'-O-methylated flavonoids 5-hydroxyflavonoids Acetals Alkyl aryl ethers Anisoles Aryl alkyl ketones Chromones Disaccharides Flavanones Hydrocarbon derivatives Methoxybenzenes Methoxyphenols O-glycosyl compounds Organic oxides Oxacyclic compounds Oxanes Phenolic glycosides Phenoxy compounds Polyols Secondary alcohols Vinylogous acids 1-benzopyran 1-hydroxy-2-unsubstituted benzenoid 1-hydroxy-4-unsubstituted benzenoid 3'-hydroxyflavonoid 4p-methoxyflavonoid-skeleton 5-hydroxyflavonoid Acetal Alcohol Alkyl aryl ether Anisole Aromatic heteropolycyclic compound Aryl alkyl ketone Aryl ketone Benzenoid Benzopyran Chromane Chromone Disaccharide Ether Flavan Flavanone Flavonoid-7-o-glycoside Glycosyl compound Hydrocarbon derivative Hydroxyflavonoid Ketone Methoxybenzene Methoxyphenol Monocyclic benzene moiety O-glycosyl compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Oxane Phenol Phenol ether Phenolic glycoside Phenoxy compound Polyol Secondary alcohol Vinylogous acid 3'-hydroxyflavanones dihydroxyflavanone disaccharide derivative flavanone glycoside flavanones monomethoxyflavanone rutinoside Solid logp -0.27 ALOGPS logs -2.36 ALOGPS solubility 2.69e+00 g/l ALOGPS melting_point Mp 258-262° (softens at 250°) logp -0.31 ChemAxon pka_strongest_acidic 8.61 ChemAxon pka_strongest_basic -3.6 ChemAxon iupac (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-3,4-dihydro-2H-1-benzopyran-4-one ChemAxon average_mass 610.5606 ChemAxon mono_mass 610.189770418 ChemAxon smiles COC1=CC=C(C=C1O)[C@@H]1CC(=O)C2=C(O1)C=C(O[C@@H]1O[C@H](CO[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]1O)C=C2O ChemAxon formula C28H34O15 ChemAxon inchi InChI=1S/C28H34O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-7,10,17,19,21-30,32-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1 ChemAxon inchikey QUQPHWDTPGMPEX-QJBIFVCTSA-N ChemAxon polar_surface_area 234.29 ChemAxon refractivity 140.77 ChemAxon polarizability 58.87 ChemAxon rotatable_bond_count 7 ChemAxon acceptor_count 15 ChemAxon donor_count 8 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::NmrOneD 4164 Specdb::MsMs 63777 Specdb::MsMs 63778 Specdb::MsMs 63779 Specdb::MsMs 120780 Specdb::MsMs 120781 Specdb::MsMs 120782 Specdb::MsMs 285743 Specdb::MsMs 285744 Specdb::MsMs 285745 Specdb::MsMs 285746 Specdb::MsMs 285747 Specdb::MsMs 285748 Specdb::MsMs 373896 Specdb::MsMs 373897 Specdb::MsMs 373898 Specdb::MsMs 373899 Specdb::MsMs 373900 Specdb::MsMs 373901 Specdb::MsMs 374891 Specdb::MsMs 436998 Specdb::MsMs 436999 Specdb::MsMs 437000 Specdb::MsMs 437001 Specdb::MsMs 437002 Specdb::MsMs 439218 HMDB03265 28775 #<Reference:0x00007f093c1640d0> #<Reference:0x000055ce33487ec8> #<Reference:0x000055ce33487d10> #<Reference:0x000055ce33487b58> #<Reference:0x000055ce334879a0> Citrus Unknown generic Cornmint Type 1 specific Mentha arvensis 292239 Fruit juice Type 2 specific Grapefruit Type 1 specific Citrus X paradisi 37656 1.101212 1.549999981 0.652424233 mg/100 g Grapefruit/Pummelo hybrid Type 1 specific Citrus paradisi X Citrus maxima 37656 0.0 0.0 0.0 mg/100 g Green bell pepper Type 1 specific Capsicum annuum 4072 Hyssop Type 1 specific Hyssopus officinalis 39324 5500.0 5500.0 5500.0 mg/100 g Lemon Type 1 specific Citrus limon 2708 21.396607 24.985714209 17.807500064 mg/100 g Lime Type 1 specific Citrus aurantiifolia 159033 13.408572 13.408572061 13.408572061 mg/100 g Linden Type 1 specific Tilia 64580 Mandarin orange (Clementine, Tangerine) Type 1 specific Citrus reticulata 85571 36.107499 36.107499361 36.107499361 mg/100 g Mentha Type 1 specific Mentha 21819 Orange bell pepper Type 1 specific Capsicum annuum 4072 Pepper Type 1 specific Capsicum annuum 4072 Pepper (C. frutescens) Type 1 specific Capsicum annuum var. annuum 40321 Peppermint Type 1 specific Mentha X piperita 34256 480.650185 480.650185196 480.650185196 mg/100 g Pummelo Type 1 specific Citrus maxima 37334 0.0 0.0 0.0 mg/100 g Red bell pepper Type 1 specific Capsicum annuum 4072 Rosemary Type 1 specific Rosmarinus officinalis 39367 Spearmint Type 1 specific Mentha spicata 29719 Sweet orange Type 1 specific Citrus sinensis 2711 43.358898 52.676666684 25.850592099 mg/100 g Welsh onion Type 1 specific Allium fistulosum 35875 0.0189 0.0189 0.0189 mg/100 g Yellow bell pepper Type 1 specific Capsicum annuum 4072 Analgesic 56 An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. Anti bradykinic 153 Anti capillary-fragility 160 Anti histaminic 331 Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Anti LDL 74 A substance that diminishes the rate of a chemical reaction. Anti leukotriene 399 A substance that diminishes the rate of a chemical reaction. Anti prostaglandin 550 A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. Anti triglyceride 668 A substance that diminishes the rate of a chemical reaction. Anti ulcer 676 One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. Anti-allergenic 102 A drug used to treat allergic reactions. Anti-DNA 234 Anti-flu 284 A substance that destroys or inhibits replication of viruses. Anti-inflammatory 370 A substance that reduces or suppresses inflammation. Anti-oxidant 502 A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324. Anti-RNA 590 Anti-stomatitic 630 Anti-vaccinia 685 A substance that destroys or inhibits replication of viruses. Anti-viral 689 A substance that destroys or inhibits replication of viruses. Anxiolytic 698 Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. Calcium antagonist 748 Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. Capillariprotective 760 Catabolic 780 Central nervous system depressant 812 A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system. Choleretic 801 Cyclooxygenase inhibitor 849 A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. Hypolipidemic 1020 Lipoxygenase inhibitor 1077 A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes. Pesticide 1210 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. Pro HLDL 1249 Vasopressor 1415