1.0 2010-04-08 22:05:29 UTC 2020-02-24 19:10:35 UTC FDB002704 8-Hydroxy-2-methoxy-6-methyl-1,4-naphthoquinone Root constituent of Diospyros kaki (Japanese persimmon) Scabies is a common, highly pruritic infestation of the skin caused by Sarcoptes scabiei (lice). It is a very contagious condition with specific lesions, such as burrows, and nonspecific lesions, such as papules, vesicles and excoriations. The typical areas of the body it affects are finger webs, scalp (hair), wrists, axillary folds, abdomen, buttocks, inframammary folds and genitalia (males). It is characterized by intense night-time itching. Scabies is spread through close personal contact (relatives, sexual partners, schoolchildren, chronically ill patients and crowded communities). Scabies infestations and the corresponding symptoms can be eliminated by killing the scabies with topical insecticides or scabicides. Lindane is a scabicide that is essentially and organochloride insecticide. 8-Hydroxy-2-methoxy-6-methyl-1,4-naphthoquinone is found in fruits. (1r,2c,3c,4t,5c,6t)-1,2,3,4,5,6-hexachlorocyclohexane (1r,2c,3t,4t,5c,6t)-1,2,3,4,5,6-hexachlorocyclohexane (1r,2r,3r,4r,5r,6r)-1,2,3,4,5,6-hexachlorocyclohexane (1R,2R,3R,4R,5S,6S)-1,2,3,4,5,6-hexachlorocyclohexane (1r,2R,3S,4r,5R,6S)-1,2,3,4,5,6-hexachlorocyclohexane (1r,2R,3S,4s,5R,6S)-1,2,3,4,5,6-hexachlorocyclohexane (1R,2R,3S,4S,5S,6S)-1,2,3,4,5,6-hexachlorocyclohexane (1s,2R,3R,4s,5S,6S)-1,2,3,4,5,6-hexachlorocyclohexane 1,2,3,4,5,6-hexachlorocyclohexane 1,2,3,4,5,6-Hexachlorocyclohexane (all stereo isomers) 1,2,3,4,5,6-Hexachlorocyclohexane (mixture of isomers) 1,2,3,4,5,6-Hexachlorocyclohexane gamma isomer 1,2,3,4,5,6-hexachlorocyclohexane, alpha isomer 1,2,3,4,5,6-Hexachlorocyclohexane, gamma-isomer 1a,2a,3b,4a,5b,6b-hexachlorocyclohexane 1a,2b,3a,4b,5a,6b-hexachlorocyclohexane 3-Methoxy-7-methyljuglone 8-Hydroxy-2-methoxy-6-methyl-1,4-naphthoquinone 8-Hydroxy-2-methoxy-6-methylnaphthalene-1,4-dione, 9CI Aalindan Aficide agrisol g-20 Agrocide agrocide 2 agrocide 6g agrocide 7 Agrocide III Agrocide WP Agronexit Alpha- BHC alpha-1,2,3,4,5,6-Hexachlorocyclohexane Alpha-benzene hexachloride Alpha-benzenehexachloride Alpha-BHC Alpha-HCH Alpha-HCH [hexachlorocyclohexanes] Alpha-hexachloran Alpha-hexachlorane Alpha-hexachlorocyclohexane Alpha-hexachlorocyclohexanes Alpha-lindane Am eisenatod Ameisenatod Ameisenmittel merck Ameisentod Aparasin Aphtiria Aphtitria Aplidal Arbitex Arcotal s BBH BCH Ben-hex Benhexachlor Benhexol bentox 10 Benzanex Benzene hexachloride Benzene hexachloride (ambiguous) Benzene hexachloride-alpha-isomer Benzene hexachloride-gamma isomer Benzene hexachloride-gamma-isomer Benzene hexachloride, all isomers Benzene-1,2,3,4,5,6-hexachloride ((Ambiguous) Benzene-cis-hexachloride Benzene-trans-hexachloride Benzenehexachloride-alpha-isomer Benzenehexachloride, mixed isomers Benzex beta-1,2,3,4,5,6-Hexachlorocyclohexane Beta-benzene hexachloride Beta-BHC Beta-HCH Beta-HCH [hexachlorocyclohexanes] Beta-hexac hlorocyclohexane Beta-hexachloran Beta-hexachlorobenzene Beta-hexachlorocyclohexane Beta-hexachlorocyclohexanes Beta-isomer Beta-lindane Bexol BHC (alpha-, beta-, gamma-) BHC (insecticide) BHC insecticide BHC or HCH Borer spray Celanex Chinoin brand of lindane Chloresene Codechine CPD with unspecified stereochemistry Cyclohexane, 1,2,3,4,5,6-hexachloro- Cyclohexane, 1,2,3,4,5,6-hexachloro-, (mixed isomers) Cyclohexane, 1,2,3,4,5,6-hexachloro-, alpha- Cyclohexane, 1,2,3,4,5,6-hexachloro-, alpha-isomer Cyclohexane, 1,2,3,4,5,6-hexachloro-, beta-isomer Cyclohexane, 1,2,3,4,5,6-hexachloro-, delta- Cyclohexane, 1,2,3,4,5,6-hexachloro-, delta-isomer Cyclohexane, 1,2,3,4,5,6-hexachloro-, gamma- Cyclohexane, 1,2,3,4,5,6-hexachloro-, gamma-isomer Cyclohexane, beta-1,2,3,4,5,6-hexachloro- Cyclohexane, delta-1,2,3,4,5,6-hexachloro- Delitex delta-(Aeeeee)-1,2,3,4,5,6-hexachlorocyclohexane delta-1,2,3,4,5,6-Hexachlorocyclohexane Delta-benzene hexachloride Delta-benzenehexachloride Delta-BHC Delta-HCH Delta-hexachlorocyclohexane Delta-lindane Detmol extract Detmol-extrakt detox 25 Devoran Dol granule Dolmix Drill tox-spezial aglukon Drilltox-spezial aglukon Entomoxan Epsilon HCH Epsilon-benzenehexachloride Epsilon-HCH Epsilon-hexachlorocyclohexane Eso derm Esoderm Exagama Fenoform forte Forlin Forst-nexen Gallogama Gamacarbatox Gamacid Gamacide Gamacide 20 Gamaphex Gamene Gamiso Gamma 666 Gamma benzene hexachloride Gamma BHC Gamma hexachlor Gamma hexachlorocyclohexane Gamma-:hexachlorocyclohexane gamma-1,2,3,4,5,6-Hexachlorocyclohexane Gamma-666 Gamma-benzene hexachloride Gamma-benzenehexachloride Gamma-benzohexachloride Gamma-BHC Gamma-BHC (lindane) Gamma-BHC benhexachlor Gamma-col Gamma-HCH Gamma-HCH [hexachlorocyclohexanes] Gamma-HCH or gamma-BHC Gamma-hexachlorane Gamma-hexachlorcyclohexanum Gamma-hexachlorobenzene Gamma-hexachlorocyclohexane Gamma-linda ne Gamma-lindane Gamma-mean 400 Gamma666 Gammahexa Gammahexane Gammalin gammalin 20 Gammaterr Gammex Gammexane Gammopaz Gamtox Geobilan geolin g 3 Gexane Gyben H.c.h HCH HCH (alpha) HCH (beta) HCH [bsi] HCH [iso] Heclotox Hecoltox Hexablanc Hexachlor Hexachloran Hexachlorane Hexachlorcyclohexan Hexachloride, benzene Hexachloride, gamma-benzene Hexachlorocyclohexane Hexachlorocyclohexane (all isomers) Hexachlorocyclohexane (mixed isomers) Hexachlorocyclohexane (mixture) Hexachlorocyclohexane (technical grade) Hexachlorocyclohexane-alpha Hexachlorocyclohexane-beta Hexachlorocyclohexane, alpha- Hexachlorocyclohexane, beta- Hexachlorocyclohexane, delta- Hexachlorocyclohexane, gamma isomer Hexachlorocyclohexane, gamma- Hexachlorocyclohexane, gamma-isomer Hexachlorocyclohexanes Hexachlorzyklohexan Hexamul Hexapoudre Hexatox Hexaverm Hexcidum Hexicide Hexyclan HGI Hilbeec h Hilbeech Hortex hungaria l7 Inexit Infectopharm brand of lindane Insecticide, BHC Isatox Isot ox Isotox Jacutin Kokotine Kwell Kwell-r Lacco hi lin Lasochron Lendine Lentox Lidenal Lindafor Lindagam Lindagrain Lindagranox Lindalo Lindam ul Lindamul Lindane Lindane (benzene hexachloroide-gamma isomer) Lindane (gamma-HCH) Lindane [hexachlorocyclohexanes] Lindane [usan:inn:ban] Lindapoudre Lindaterra Lindatox Lindex Lindosep Lintox Linvur Lorexane Mglawik l milbol 49 Mszycol Neo-scabicidol Nexen FB Nexen-FB Nexi t-stark Nexit Nexit-stark Nexol-e Nicochloran Novigam Novigan Omnitox Ovadziak Owadziak Pedraczak Pflanzol Pharmascience brand of lindane PLK PMS lindane PMS-lindane Pmslindane Quellada Sang gamma Scabecid Scabene Scabisan Silvanol Spritz-rapidin Spritzlindane Spruehpflanzol Stiefel brand of lindane Streunex Submar T-HCH TBH Technical HCH Technical hexachlorocyclohexane Tetocid Trans-alpha-benzenehexachloride Tri-6 Trives-t Verindal ultra Viton C12H10O4 218.2054 218.057908808 8-hydroxy-2-methoxy-6-methyl-1,4-dihydronaphthalene-1,4-dione 8-hydroxy-2-methoxy-6-methylnaphthalene-1,4-dione 1589-92-0 COC1=CC(=O)C2=C(C(O)=CC(C)=C2)C1=O InChI=1S/C12H10O4/c1-6-3-7-8(13)5-10(16-2)12(15)11(7)9(14)4-6/h3-5,14H,1-2H3 KDBWUCIHUALFON-UHFFFAOYSA-N belongs to the class of organic compounds known as naphthoquinones. Naphthoquinones are compounds containing a naphthohydroquinone moiety, which consists of a benzene ring linearly fused to a bezene-1,4-dione (quinone). Naphthoquinones Organic compounds Benzenoids Naphthalenes Naphthoquinones Aromatic homopolycyclic compounds 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids Aryl ketones Hydrocarbon derivatives Organic oxides Quinones Vinylogous acids Vinylogous esters 1-hydroxy-2-unsubstituted benzenoid 1-hydroxy-4-unsubstituted benzenoid Aromatic homopolycyclic compound Aryl ketone Hydrocarbon derivative Ketone Naphthoquinone Organic oxide Organic oxygen compound Organooxygen compound Quinone Vinylogous acid Vinylogous ester logp 2.07 ALOGPS logs -2.39 ALOGPS solubility 8.91e-01 g/l ALOGPS melting_point Mp 210-211° (209-210°) logp 1.95 ChemAxon pka_strongest_acidic 9.39 ChemAxon pka_strongest_basic -4.5 ChemAxon iupac 8-hydroxy-2-methoxy-6-methyl-1,4-dihydronaphthalene-1,4-dione ChemAxon average_mass 218.2054 ChemAxon mono_mass 218.057908808 ChemAxon smiles COC1=CC(=O)C2=C(C(O)=CC(C)=C2)C1=O ChemAxon formula C12H10O4 ChemAxon inchi InChI=1S/C12H10O4/c1-6-3-7-8(13)5-10(16-2)12(15)11(7)9(14)4-6/h3-5,14H,1-2H3 ChemAxon inchikey KDBWUCIHUALFON-UHFFFAOYSA-N ChemAxon polar_surface_area 63.6 ChemAxon refractivity 59.92 ChemAxon polarizability 21.61 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 4 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 24672 Specdb::CMs 42145 Specdb::CMs 149629 Specdb::MsMs 60864 Specdb::MsMs 60865 Specdb::MsMs 60866 Specdb::MsMs 117291 Specdb::MsMs 117292 Specdb::MsMs 117293 Specdb::MsMs 2470260 Specdb::MsMs 2470261 Specdb::MsMs 2470262 Specdb::MsMs 2492660 Specdb::MsMs 2492661 Specdb::MsMs 2492662 HMDB30769 32888 #<Reference:0x000055ce323fe390> #<Reference:0x000055ce323fe1d8> #<Reference:0x000055ce323fe020> #<Reference:0x000055ce323fde68> #<Reference:0x000055ce323fdcb0> #<Reference:0x000055ce323fdaf8> #<Reference:0x000055ce323fd940> #<Reference:0x000055ce323fd788> #<Reference:0x000055ce323fd5d0> #<Reference:0x000055ce323fd418> #<Reference:0x000055ce323fd260> #<Reference:0x000055ce323fd0a8> #<Reference:0x000055ce323fcef0> #<Reference:0x000055ce323fcd38> #<Reference:0x000055ce323fcb80> #<Reference:0x000055ce323fc9c8> #<Reference:0x000055ce323fc810> #<Reference:0x000055ce323fc658> #<Reference:0x000055ce323fc4a0> #<Reference:0x000055ce323fc2e8> #<Reference:0x000055ce323fc130> #<Reference:0x000055ce323fbf28> #<Reference:0x000055ce323fbd70> #<Reference:0x000055ce323fbbb8> Fruits Unknown generic Milk (Cow) Type 2 specific 0.02517 0.0677 0.00138 uM