1.02010-04-08 22:05:29 UTC2019-11-26 02:57:51 UTCFDB002711HyperinOccurs widely in plants, e.g. in apple peel and Hypericum perforatum (St John's wort)
Hyperoside is the 3-O-galactoside of quercetin. It is a medicinally active compound that can be isolated from Drosera rotundifolia, from the Stachys plant, from Prunella vulgaris, from Rumex acetosella and from St John's wort. Hyperin is found in many foods, some of which are apricot, pear, guava, and common buckwheat.2-(3,4-Dihydroxyphenyl)-3-(b-D-galactopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one2-(3,4-Dihydroxyphenyl)-3-(beta-D-galactopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one2-(3,4-Dihydroxyphenyl)-3-(β-D-galactopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one3-O-b-D-Galactopyranosyloxy-3',4',5,7-tetrahydroxyflavoneHyperinHyperosideHyperozideJyperinQuercetin 3-beta-D-galactopyranosideQuercetin 3-D-galactosideQuercetin 3-galactosideQuercetin 3-O-β-D-galactopyranosideQuercetin 3-O-beta-D-galactopyranosideQuercetin 3-O-beta-D-galactosideQuercetin 3-O-galactosideC21H20O12464.3763464.0954761042-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-onehyperoside482-36-0OC[C@H]1O[C@@H](OC2=C(OC3=C(C(O)=CC(O)=C3)C2=O)C2=CC(O)=C(O)C=C2)[C@H](O)[C@@H](O)[C@H]1OInChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15+,17+,18-,21+/m1/s1OVSQVDMCBVZWGM-DTGCRPNFSA-N belongs to the class of organic compounds known as flavonoid-3-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C3-position.Flavonoid-3-O-glycosidesOrganic compoundsPhenylpropanoids and polyketidesFlavonoidsFlavonoid glycosidesAromatic heteropolycyclic compounds1-hydroxy-2-unsubstituted benzenoids1-hydroxy-4-unsubstituted benzenoids3'-hydroxyflavonoids4'-hydroxyflavonoids5-hydroxyflavonoids7-hydroxyflavonoidsAcetalsBenzene and substituted derivativesCatecholsChromonesFlavonesHeteroaromatic compoundsHexosesHydrocarbon derivativesO-glycosyl compoundsOrganic oxidesOxacyclic compoundsOxanesPolyolsPrimary alcoholsPyranones and derivativesSecondary alcoholsVinylogous acids1-benzopyran1-hydroxy-2-unsubstituted benzenoid1-hydroxy-4-unsubstituted benzenoid3'-hydroxyflavonoid4'-hydroxyflavonoid5-hydroxyflavonoid7-hydroxyflavonoidAcetalAlcoholAromatic heteropolycyclic compoundBenzenoidBenzopyranCatecholChromoneFlavoneFlavonoid-3-o-glycosideGlycosyl compoundHeteroaromatic compoundHexose monosaccharideHydrocarbon derivativeHydroxyflavonoidMonocyclic benzene moietyMonosaccharideO-glycosyl compoundOrganic oxideOrganic oxygen compoundOrganoheterocyclic compoundOrganooxygen compoundOxacycleOxanePhenolPolyolPrimary alcoholPyranPyranoneSecondary alcoholVinylogous acidFlavones and Flavonolsbeta-D-galactosideflavonolsmonosaccharide derivativequercetin O-glycosidetetrahydroxyflavonelogp0.47logs-2.38solubility1.95e+00 g/lmelting_pointMp 232-233° dec.logp-0.14pka_strongest_acidic6.37pka_strongest_basic-3iupac2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-oneaverage_mass464.3763mono_mass464.095476104smilesOC[C@H]1O[C@@H](OC2=C(OC3=C(C(O)=CC(O)=C3)C2=O)C2=CC(O)=C(O)C=C2)[C@H](O)[C@@H](O)[C@H]1OformulaC21H20O12inchiInChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15+,17+,18-,21+/m1/s1inchikeyOVSQVDMCBVZWGM-DTGCRPNFSA-Npolar_surface_area206.6refractivity109.28polarizability43.37rotatable_bond_count4acceptor_count12donor_count8physiological_charge-1formal_charge0Specdb::NmrOneD17862Specdb::NmrOneD17863Specdb::NmrOneD17864Specdb::NmrOneD17865Specdb::NmrOneD17866Specdb::NmrOneD17867Specdb::NmrOneD17868Specdb::NmrOneD17869Specdb::NmrOneD17870Specdb::NmrOneD17871Specdb::NmrOneD17872Specdb::NmrOneD17873Specdb::NmrOneD17874Specdb::NmrOneD17875Specdb::NmrOneD17876Specdb::NmrOneD17877Specdb::NmrOneD17878Specdb::NmrOneD17879Specdb::NmrOneD17880Specdb::NmrOneD17881Specdb::CMs10038Specdb::CMs42151Specdb::CMs171824Specdb::MsMs87396Specdb::MsMs87397Specdb::MsMs87398Specdb::MsMs149892Specdb::MsMs149893Specdb::MsMs149894Specdb::MsMs374385Specdb::MsMs436965Specdb::MsMs436966Specdb::MsMs436967Specdb::MsMs436968Specdb::MsMs436969Specdb::MsMs438970Specdb::MsMs438971Specdb::MsMs438972Specdb::MsMs438973Specdb::MsMs439147Specdb::MsMs439286Specdb::MsMs440545Specdb::MsMs444974Specdb::MsMs444975Specdb::MsMs444976Specdb::MsMs444977Specdb::MsMs444978Specdb::MsMs447867HMDB30775#<Reference:0x00005556762f23e0>Alcoholic beveragesUnknowngenericAllspiceType 1specificPimenta dioica375272AlmondType 1specificPrunus dulcis37550.7894750.7894749880.789474988mg/100 gAmerican cranberryType 1specificVaccinium macrocarpon1375010.81642310.81642341610.816423416mg/100 gAppleType 1specificMalus pumila2832100.6390112.3576470990.0mg/100 gApricotType 1specificPrunus armeniaca36596BilberryType 1specificVaccinium myrtillus180763Black chokeberryType 1specificPhotinia melanocarpa66133946.46145646.46145629946.461456299mg/100 gBlack elderberryType 1specificSambucus nigra4202Black teaType 11.9635154.1790728570.737071732mg/100 gBlackberryType 1specificRubusCarawayType 1specificCarum carvi48032ChicoryType 1specificCichorium intybus13427ClovesType 1specificSyzygium aromaticum219868Cocoa beanType 1specificTheobroma cacao3641Common buckwheatType 1specificFagopyrum esculentum3617Common grapeType 1specificVitis vinifera297600.940.9399999380.939999938mg/100 gCommon walnutType 1specificJuglans regia51240200.0200.0200.0mg/100 gDillType 1specificAnethum graveolens40922EndiveType 1specificCichorium endivia1142800.00.00.0mg/100 gEuropean plumType 1specificPrunus domestica37580.2730920.2730916710.273091671mg/100 gFox grapeType 1specificVitis labrusca1033552.612.6100001342.610000134mg/100 gFruit juiceType 2specificGerman camomileType 1specificMatricaria recutita127986Green teaType 11.9635154.1790728570.737071732mg/100 gGuavaType 1specificPsidium guajava120290Herbal teaType 1Herbs and SpicesUnknowngenericHighbush blueberryType 1specificVaccinium corymbosum692668.9925168.9925163598.992516359mg/100 gHorseradishType 1specificArmoracia rusticana3704LettuceType 1specificLactuca sativa42360.1216340.1382781420.104988965mg/100 gLingonberryType 1specificVaccinium vitis-idaea18077213.22860913.22860908513.228609085mg/100 gLoquatType 1specificEriobotrya japonica32224NectarineType 1specificPrunus persica var. nucipersica3238510.5786710.5786710280.578671028mg/100 gPeach (var.)Type 1specificPrunus persica var. persica3238520.7100490.7100490990.710049099mg/100 gPearType 1specificPyrus communis232110.0350.070.0mg/100 gPepper (Spice)Type 1specificPiper nigrum13216PomesUnknowngenericQuinceType 1specificCydonia oblonga366100.2676960.7185714190.0mg/100 gRed raspberryType 1specificRubus idaeus322470.1996150.199615380.19961538mg/100 gRed teaType 1RowanberryType 1specificSorbus aucuparia365992.5043712.5043706892.504370689mg/100 gRubus (Blackberry, Raspberry)Type 1specificRubus232164.1016674.1016666294.101666629mg/100 gSacred lotusType 1specificNelumbo nucifera4432Sea-buckthornberryType 1specificHippophae rhamnoides1935160.00.00.0mg/100 gSorrelType 1specificRumex acetosa4124143.543.543.5mg/100 gSour cherryType 1specificPrunus cerasus140311SpinachType 1specificSpinacia oleracea3562Star aniseType 1specificIllicium verum124778Summer grapeType 1specificVitis aestivalis36050.850.8500000240.850000024mg/100 gTarragonType 1specificArtemisia dracunculus72341TeaType 1specificCamellia sinensis44421.9635154.1790728570.737071732mg/100 gWild celeryType 1specificApium graveolens4045aldose reductase inhibitor40An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21).analgesic56An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.anti aging95Any substance introduced into a living organism with therapeutic or diagnostic purpose.anti bacterial145A substance that kills or slows the growth of bacteria.anti cancer159A substance that inhibits or prevents the proliferation of neoplasms.anti capillary-fragility160anti dermatitic225A drug used to treat or prevent skin disorders or for the routine care of skin.anti elastase250A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.anti flu284A substance that destroys or inhibits replication of viruses.anti hepatotoxic328Any compound that is able to prevent damage to the liver.anti inflammatory370A substance that reduces or suppresses inflammation.anti ischemic377Any substance introduced into a living organism with therapeutic or diagnostic purpose.anti nociceptive484A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.anti radicular572anti tussive674Any substance introduced into a living organism with therapeutic or diagnostic purpose.anti viral689A substance that destroys or inhibits replication of viruses.anti wrinkle693antioxidant502A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324.calcium antagonist748Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances.cAMP inhibitor752A substance that diminishes the rate of a chemical reaction.cancer preventive754A substance that inhibits or prevents the proliferation of neoplasms.capillarifortificant758capillarigenic759cyclooxygenase activator848diuretic883An agent that promotes the excretion of urine through its effects on kidney function.hepatoprotective981Any compound that is able to prevent damage to the liver.hypotensive1021pesticide1210Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.tissue thromboplastin inhibitor1362A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.xanthine oxidase inhibitor1431An EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor that interferes with the action of xanthine oxidase (EC 1.17.3.2).