1.0 2010-04-08 22:05:30 UTC 2025-11-18 22:40:18 UTC FDB002751 Nevadensin Nevadensin, also known as pedunculin or 5,7-hydroxy-4',6,8-trimethoxyflavone, is a member of the class of compounds known as 8-o-methylated flavonoids. 8-o-methylated flavonoids are flavonoids with methoxy groups attached to the C8 atom of the flavonoid backbone. Thus, nevadensin is considered to be a flavonoid lipid molecule. Nevadensin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Nevadensin can be found in peppermint and sweet basil, which makes nevadensin a potential biomarker for the consumption of these food products. 5,7-Dihydroxy-4',6,8-trimethoxyflavone Lysionotin Nevadensin Nevadensin a Nevadensin? Pedunculin C18H16O7 344.3154 344.089602866 5,7-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one nevadensin 10176-66-6 COC1=CC=C(C=C1)C1=CC(=O)C2=C(O1)C(OC)=C(O)C(OC)=C2O InChI=1S/C18H16O7/c1-22-10-6-4-9(5-7-10)12-8-11(19)13-14(20)17(23-2)15(21)18(24-3)16(13)25-12/h4-8,20-21H,1-3H3 KRFBMPVGAYGGJE-UHFFFAOYSA-N belongs to the class of organic compounds known as 8-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C8 atom of the flavonoid backbone. 8-O-methylated flavonoids Organic compounds Phenylpropanoids and polyketides Flavonoids O-methylated flavonoids Aromatic heteropolycyclic compounds 4'-O-methylated flavonoids 5-hydroxyflavonoids 6-O-methylated flavonoids 7-hydroxyflavonoids Alkyl aryl ethers Anisoles Chromones Flavones Heteroaromatic compounds Hydrocarbon derivatives Methoxybenzenes Organic oxides Oxacyclic compounds Phenoxy compounds Pyranones and derivatives Vinylogous acids 1-benzopyran 4p-methoxyflavonoid-skeleton 5-hydroxyflavonoid 6-methoxyflavonoid-skeleton 7-hydroxyflavonoid 8-methoxyflavonoid-skeleton Alkyl aryl ether Anisole Aromatic heteropolycyclic compound Benzenoid Benzopyran Chromone Ether Flavone Heteroaromatic compound Hydrocarbon derivative Hydroxyflavonoid Methoxybenzene Monocyclic benzene moiety Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Phenol ether Phenoxy compound Pyran Pyranone Vinylogous acid Flavones and Flavonols Flavones and Flavonols dihydroxyflavone flavones trimethoxyflavone logp 2.94 ALOGPS logs -3.88 ALOGPS solubility 4.52e-02 g/l ALOGPS melting_point Mp 198-199° logp 2.54 ChemAxon pka_strongest_acidic 6.63 ChemAxon pka_strongest_basic -4.2 ChemAxon iupac 5,7-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one ChemAxon average_mass 344.3154 ChemAxon mono_mass 344.089602866 ChemAxon smiles COC1=CC=C(C=C1)C1=CC(=O)C2=C(O1)C(OC)=C(O)C(OC)=C2O ChemAxon formula C18H16O7 ChemAxon inchi InChI=1S/C18H16O7/c1-22-10-6-4-9(5-7-10)12-8-11(19)13-14(20)17(23-2)15(21)18(24-3)16(13)25-12/h4-8,20-21H,1-3H3 ChemAxon inchikey KRFBMPVGAYGGJE-UHFFFAOYSA-N ChemAxon polar_surface_area 94.45 ChemAxon refractivity 90.32 ChemAxon polarizability 34.73 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 7 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 115727 Specdb::CMs 130189 Specdb::CMs 950425 Specdb::CMs 950426 Specdb::CMs 950427 Specdb::CMs 950428 Specdb::CMs 950429 Specdb::CMs 950430 Specdb::MsMs 84810 Specdb::MsMs 84811 Specdb::MsMs 84812 Specdb::MsMs 146757 Specdb::MsMs 146758 Specdb::MsMs 146759 Specdb::MsMs 285859 Specdb::MsMs 285860 Specdb::MsMs 285861 Specdb::MsMs 285862 Specdb::MsMs 285863 Specdb::MsMs 285864 Specdb::MsMs 2238780 Specdb::MsMs 2240763 Specdb::MsMs 2240914 Specdb::MsMs 2242825 Specdb::MsMs 2243036 Peppermint Type 1 specific Mentha X piperita 34256 Sweet basil Type 1 specific Ocimum basilicum 39350 Aldose reductase inhibitor 40 An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21). Anti-inflammatory 370 A substance that reduces or suppresses inflammation. Anti-tubercular 670 A substance that kills or slows the growth of bacteria. Anti-tussive 674 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Expectorant 925 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Pesticide 1210 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.