1.02010-04-08 22:05:30 UTC2019-11-26 02:57:55 UTCFDB002751NevadensinNevadensin, also known as pedunculin or 5,7-hydroxy-4',6,8-trimethoxyflavone, is a member of the class of compounds known as 8-o-methylated flavonoids. 8-o-methylated flavonoids are flavonoids with methoxy groups attached to the C8 atom of the flavonoid backbone. Thus, nevadensin is considered to be a flavonoid lipid molecule. Nevadensin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Nevadensin can be found in peppermint and sweet basil, which makes nevadensin a potential biomarker for the consumption of these food products. 5,7-Dihydroxy-4',6,8-trimethoxyflavoneLysionotinNevadensinNevadensin aNevadensin?PedunculinC18H16O7344.3154344.08960286610176-66-6COC1=CC=C(C=C1)C1=CC(=O)C2=C(O1)C(OC)=C(O)C(OC)=C2OInChI=1S/C18H16O7/c1-22-10-6-4-9(5-7-10)12-8-11(19)13-14(20)17(23-2)15(21)18(24-3)16(13)25-12/h4-8,20-21H,1-3H3KRFBMPVGAYGGJE-UHFFFAOYSA-N belongs to the class of organic compounds known as 8-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C8 atom of the flavonoid backbone.8-O-methylated flavonoidsOrganic compoundsPhenylpropanoids and polyketidesFlavonoidsO-methylated flavonoidsAromatic heteropolycyclic compounds4'-O-methylated flavonoids5-hydroxyflavonoids6-O-methylated flavonoids7-hydroxyflavonoidsAlkyl aryl ethersAnisolesChromonesFlavonesHeteroaromatic compoundsHydrocarbon derivativesMethoxybenzenesOrganic oxidesOxacyclic compoundsPhenoxy compoundsPyranones and derivativesVinylogous acids1-benzopyran4p-methoxyflavonoid-skeleton5-hydroxyflavonoid6-methoxyflavonoid-skeleton7-hydroxyflavonoid8-methoxyflavonoid-skeletonAlkyl aryl etherAnisoleAromatic heteropolycyclic compoundBenzenoidBenzopyranChromoneEtherFlavoneHeteroaromatic compoundHydrocarbon derivativeHydroxyflavonoidMethoxybenzeneMonocyclic benzene moietyOrganic oxideOrganic oxygen compoundOrganoheterocyclic compoundOrganooxygen compoundOxacyclePhenol etherPhenoxy compoundPyranPyranoneVinylogous acidFlavones and FlavonolsFlavones and Flavonolsdihydroxyflavoneflavonestrimethoxyflavonemelting_pointMp 198-199°average_mass344.3154mono_mass344.089602866smilesCOC1=CC=C(C=C1)C1=CC(=O)C2=C(O1)C(OC)=C(O)C(OC)=C2OformulaC18H16O7inchiInChI=1S/C18H16O7/c1-22-10-6-4-9(5-7-10)12-8-11(19)13-14(20)17(23-2)15(21)18(24-3)16(13)25-12/h4-8,20-21H,1-3H3inchikeyKRFBMPVGAYGGJE-UHFFFAOYSA-NSpecdb::CMs115727Specdb::CMs130189Specdb::CMs950425Specdb::CMs950426Specdb::CMs950427Specdb::CMs950428Specdb::CMs950429Specdb::CMs950430Specdb::MsMs84810Specdb::MsMs84811Specdb::MsMs84812Specdb::MsMs146757Specdb::MsMs146758Specdb::MsMs146759Specdb::MsMs285859Specdb::MsMs285860Specdb::MsMs285861Specdb::MsMs285862Specdb::MsMs285863Specdb::MsMs285864Specdb::MsMs2238780Specdb::MsMs2240763Specdb::MsMs2240914Specdb::MsMs2242825Specdb::MsMs2243036PeppermintType 1specificMentha X piperita34256Sweet basilType 1specificOcimum basilicum39350aldose reductase inhibitor40An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21).anti inflammatory370A substance that reduces or suppresses inflammation.anti tubercular670A substance that kills or slows the growth of bacteria.anti tussive674Any substance introduced into a living organism with therapeutic or diagnostic purpose.expectorant925Any substance introduced into a living organism with therapeutic or diagnostic purpose.pesticide1210Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.