1.02010-04-08 22:05:31 UTC2020-02-24 19:10:37 UTCFDB002776AesculinVitamin C2 is generally considered a bioflavanoid, related to vitamin P
Aesculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and in daphnin (the dark green resin of Daphne mezereum). Aesculin is found in many foods, some of which are barley, mugwort, chicory, and lentils.6,7-Dihydroxycoumarin 6-glucosideAesculinBicolorinCrataeginEnallachromeEscosylEsculetin 6-β-D-glucosideEsculetin 6-b-D-glucosideEsculetin 6-beta-D-glucosideEsculetin 6-O-glucosideEsculinEsculineEsculosidePolychromPolychromeVitamin C2C15H16O9340.2821340.079432117-hydroxy-6-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-oneesculin531-75-9OCC1OC(OC2=C(O)C=C3OC(=O)C=CC3=C2)C(O)C(O)C1OInChI=1S/C15H16O9/c16-5-10-12(19)13(20)14(21)15(24-10)23-9-3-6-1-2-11(18)22-8(6)4-7(9)17/h1-4,10,12-17,19-21H,5H2XHCADAYNFIFUHF-UHFFFAOYSA-N belongs to the class of organic compounds known as coumarin glycosides. These are aromatic compounds containing a carbohydrate moiety glycosidically bound to a coumarin moiety.Coumarin glycosidesOrganic compoundsPhenylpropanoids and polyketidesCoumarins and derivativesCoumarin glycosidesAromatic heteropolycyclic compounds1-benzopyrans1-hydroxy-2-unsubstituted benzenoids7-hydroxycoumarinsAcetalsHeteroaromatic compoundsHexosesHydrocarbon derivativesLactonesO-glycosyl compoundsOrganic oxidesOxacyclic compoundsOxanesPhenolic glycosidesPolyolsPrimary alcoholsPyranones and derivativesSecondary alcohols1-benzopyran1-hydroxy-2-unsubstituted benzenoid7-hydroxycoumarinAcetalAlcoholAromatic heteropolycyclic compoundBenzenoidBenzopyranCoumarin o-glycosideCoumarin-6-o-glycosideGlycosyl compoundHeteroaromatic compoundHexose monosaccharideHydrocarbon derivativeHydroxycoumarinLactoneMonosaccharideO-glycosyl compoundOrganic oxideOrganic oxygen compoundOrganoheterocyclic compoundOrganooxygen compoundOxacycleOxanePhenolic glycosidePolyolPrimary alcoholPyranPyranoneSecondary alcohola small moleculelogp-0.53logs-1.52solubility1.03e+01 g/lmelting_pointMp 205°logp-1.1pka_strongest_acidic8.12pka_strongest_basic-3iupac7-hydroxy-6-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-oneaverage_mass340.2821mono_mass340.07943211smilesOCC1OC(OC2=C(O)C=C3OC(=O)C=CC3=C2)C(O)C(O)C1OformulaC15H16O9inchiInChI=1S/C15H16O9/c16-5-10-12(19)13(20)14(21)15(24-10)23-9-3-6-1-2-11(18)22-8(6)4-7(9)17/h1-4,10,12-17,19-21H,5H2inchikeyXHCADAYNFIFUHF-UHFFFAOYSA-Npolar_surface_area145.91refractivity77.65polarizability31.59rotatable_bond_count3acceptor_count8donor_count5physiological_charge0formal_charge0Specdb::CMs10753Specdb::CMs42188Specdb::MsMs439429Specdb::MsMs439430Specdb::MsMs439431Specdb::MsMs447314Specdb::MsMs449456Specdb::MsMs449461Specdb::MsMs17672Specdb::MsMs17673Specdb::MsMs17674Specdb::MsMs11000Specdb::MsMs11001Specdb::MsMs11002HMDB30820#<Reference:0x0000555675e4b9b8>BarleyType 1specificHordeum vulgare4513BeerType 2specific0.016250.0162500010.016250001mg/100 gChicoryType 1specificCichorium intybus13427Common beanType 1specificPhaseolus vulgaris3885Grape wineType 2specific0.00.00.0mg/100 gLentilsType 1genericLens culinaris3864MugwortType 1specificArtemisia vulgaris4220OliveType 1specificOlea europaea4146Sweet basilType 1specificOcimum basilicum39350aldose reductase inhibitor40An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21).analgesic56An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.anti acrocyanotic79Any substance introduced into a living organism with therapeutic or diagnostic purpose.anti aging95Any substance introduced into a living organism with therapeutic or diagnostic purpose.anti alopecic104Any substance introduced into a living organism with therapeutic or diagnostic purpose.anti arthritic131Any substance introduced into a living organism with therapeutic or diagnostic purpose.anti capillary-fragility160anti cellulitic170Any substance introduced into a living organism with therapeutic or diagnostic purpose.anti CVS214anti dermatitic225A drug used to treat or prevent skin disorders or for the routine care of skin.anti erythemic268A drug used to treat or prevent skin disorders or for the routine care of skin.anti hemorrhoidal322Any substance introduced into a living organism with therapeutic or diagnostic purpose.anti histaminic331Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.anti inflammatory370A substance that reduces or suppresses inflammation.anti panniculopathic506anti pyretic567A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.anti Raynaud's573Any substance introduced into a living organism with therapeutic or diagnostic purpose.anti seborrheic600Any substance introduced into a living organism with therapeutic or diagnostic purpose.antioxidant502A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324.bacteristat725A substance that kills or slows the growth of bacteria.cancer preventive754A substance that inhibits or prevents the proliferation of neoplasms.cardiotonic771A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.choleretic801cosmetic838The role played by a substance in enhancing the appearance or odour of the human body; a name given to the substance itself or to a component of it.diuretic883An agent that promotes the excretion of urine through its effects on kidney function.hypertensive1007lipoxygenase inhibitor1077A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes.microvasculokinetic1104paralytic1196sunscreen1337Any substance introduced into a living organism with therapeutic or diagnostic purpose.toxic1371A role played by the molecular entity or part thereof which causes the development of a pathological process.vasoprotective1416